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Magnesium in PDB 6wic: Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate
Enzymatic activity of Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate
All present enzymatic activity of Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate, PDB code: 6wic
was solved by
A.M.Kaminski,
T.A.Kunkel,
L.C.Pedersen,
K.Bebenek,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 34.88 / 1.55 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 60.134, 62.233, 118.054, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 16.6 / 17.9 |
Other elements in 6wic:
The structure of Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate also contains other interesting chemical elements:
| Potassium | (K) | 1 atom |
| Chlorine | (Cl) | 1 atom |
| Sodium | (Na) | 1 atom |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate
(pdb code 6wic). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate, PDB code: 6wic:
Jump to Magnesium binding site number: 1; 2;
In total 2 binding sites of Magnesium where determined in the Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate, PDB code: 6wic:
Jump to Magnesium binding site number: 1; 2;
Magnesium binding site 1 out of 2 in 6wic
Go back to
Magnesium Binding Sites List in 6wic
Magnesium binding site 1 out
of 2 in the Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate within 5.0Å range:
|
Magnesium binding site 2 out of 2 in 6wic
Go back to
Magnesium Binding Sites List in 6wic
Magnesium binding site 2 out
of 2 in the Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Pre-Catalytic Quaternary Complex of Human Polymerase Mu on A Complementary Dna Double-Strand Break Substrate within 5.0Å range:
|
Reference:
A.M.Kaminski,
J.M.Pryor,
D.A.Ramsden,
T.A.Kunkel,
L.C.Pedersen,
K.Bebenek.
Structural Snapshots of Human Dna Polymerase Mu Engaged on A Dna Double-Strand Break. Nat Commun V. 11 4784 2020.
ISSN: ESSN 2041-1723
PubMed: 32963245
DOI: 10.1038/S41467-020-18506-5
Page generated: Tue Oct 1 23:00:17 2024
ISSN: ESSN 2041-1723
PubMed: 32963245
DOI: 10.1038/S41467-020-18506-5
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