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Magnesium in PDB 7aop: Structure of NUDT15 in Complex with Inhibitor TH8321Enzymatic activity of Structure of NUDT15 in Complex with Inhibitor TH8321
All present enzymatic activity of Structure of NUDT15 in Complex with Inhibitor TH8321:
3.6.1.9; Protein crystallography data
The structure of Structure of NUDT15 in Complex with Inhibitor TH8321, PDB code: 7aop
was solved by
D.Rehling,
S.M.Zhang,
T.Helleday,
P.Stenmark,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Structure of NUDT15 in Complex with Inhibitor TH8321
(pdb code 7aop). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of NUDT15 in Complex with Inhibitor TH8321, PDB code: 7aop: Magnesium binding site 1 out of 1 in 7aopGo back to Magnesium Binding Sites List in 7aop
Magnesium binding site 1 out
of 1 in the Structure of NUDT15 in Complex with Inhibitor TH8321
Mono view Stereo pair view
Reference:
S.M.Zhang,
D.Rehling,
A.-S.Jemth,
A.Throup,
N.Landazuri,
I.Almlof,
M.Goettmann,
N.C.K.Valerie,
S.R.Borhade,
P.Wakchaure,
B.D.G.Page,
M.Desroses,
E.J.Homan,
M.Scobie,
S.G.Rudd,
U.Warpman Berglund,
C.Soderberg-Naucler,
P.Stenmark,
T.Helleday.
NUDT15-Mediated Hydrolysis Limits the Efficacy of Anti-Hcmv Drug Ganciclovir Cell Chem Biol 2021.
Page generated: Sun Jul 11 15:42:08 2021
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