Magnesium in PDB 7jpn: Cryo-Em Structure of Arpin-Bound ARP2/3 Complex

The binding sites of Magnesium atom in the Cryo-Em Structure of Arpin-Bound ARP2/3 Complex (pdb code 7jpn). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Cryo-Em Structure of Arpin-Bound ARP2/3 Complex, PDB code: 7jpn:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Cryo-Em Structure of Arpin-Bound ARP2/3 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Arpin-Bound ARP2/3 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:52.6 occ:1.00 O2B A:ATP502 1.9 58.1 1.0 O1G A:ATP502 2.7 58.1 1.0 PB A:ATP502 3.2 58.1 1.0 CG2 A:THR14 3.3 55.7 1.0 O3B A:ATP502 3.3 58.1 1.0 PG A:ATP502 3.6 58.1 1.0 N A:THR14 3.8 55.7 1.0 O1B A:ATP502 4.1 58.1 1.0 O3A A:ATP502 4.2 58.1 1.0 CB A:THR14 4.3 55.7 1.0 CA A:GLY13 4.4 57.3 1.0 N A:ASP172 4.4 60.5 1.0 O2G A:ATP502 4.4 58.1 1.0 CA A:GLY171 4.5 58.9 1.0 N A:GLY173 4.5 59.3 1.0 C A:GLY13 4.6 57.3 1.0 CA A:THR14 4.6 55.7 1.0 O3G A:ATP502 4.8 58.1 1.0 OD2 A:ASP169 4.9 54.4 1.0 N A:GLY171 4.9 58.9 1.0 C A:GLY171 5.0 58.9 1.0

Magnesium binding site 2 out of 2 in the Cryo-Em Structure of Arpin-Bound ARP2/3 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of Arpin-Bound ARP2/3 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg501 b:70.2 occ:1.00 OD1 B:ASP158 2.2 61.6 1.0 O1B B:ATP502 2.7 72.5 1.0 CG B:ASP158 3.2 61.6 1.0 OD2 B:ASP158 3.6 61.6 1.0 O1A B:ATP502 3.7 72.5 1.0 OE1 B:GLN141 3.9 85.5 1.0 CA B:GLY305 4.0 61.5 1.0 PB B:ATP502 4.1 72.5 1.0 CB B:ASP158 4.5 61.6 1.0 O2B B:ATP502 4.7 72.5 1.0 N B:GLY305 4.7 61.5 1.0 CA B:GLY160 4.8 64.7 1.0 O3A B:ATP502 4.8 72.5 1.0 PA B:ATP502 4.8 72.5 1.0 N B:GLY160 4.9 64.7 1.0 O B:SER159 4.9 62.0 1.0 C B:SER159 5.0 62.0 1.0 CD B:GLN141 5.0 85.5 1.0

F.E.Fregoso, T.Van Eeuwen, G.Simanov, G.Rebowski, M.Boczkowska, A.Zimmet, A.M.Gautreau, R.Dominguez. Molecular Mechanism of ARP2/3 Complex Inhibition By Arpin. Nat Commun V. 13 628 2022.
ISSN: ESSN 2041-1723
PubMed: 35110533
DOI: 10.1038/S41467-022-28112-2