Magnesium in PDB 7lfo: Protein Tyrosine Phosphatase 1B

Enzymatic activity of Protein Tyrosine Phosphatase 1B

All present enzymatic activity of Protein Tyrosine Phosphatase 1B:
3.1.3.48;

Protein crystallography data

The structure of Protein Tyrosine Phosphatase 1B, PDB code: 7lfo was solved by A.Sarkar, E.Y.Kim, A.Hongdusit, B.Sankaran, J.M.Fox, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 61.58 / 1.94
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 88.023, 88.023, 104.494, 90, 90, 120
R / Rfree (%) 20 / 24.3

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Protein Tyrosine Phosphatase 1B (pdb code 7lfo). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Protein Tyrosine Phosphatase 1B, PDB code: 7lfo:

Magnesium binding site 1 out of 1 in 7lfo

Go back to Magnesium Binding Sites List in 7lfo
Magnesium binding site 1 out of 1 in the Protein Tyrosine Phosphatase 1B


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Protein Tyrosine Phosphatase 1B within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg401

b:64.4
occ:1.00
OE2 A:GLU130 4.0 46.7 1.0
O A:HOH616 4.0 55.2 1.0
OE1 A:GLU130 4.0 47.8 1.0
OE2 A:GLU129 4.0 46.4 1.0
CD A:GLU130 4.5 46.6 1.0

Reference:

A.Sarkar, E.Y.Kim, T.Jang, A.Hongdusit, H.Kim, J.M.Choi, J.M.Fox. Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products. Acs Synth Biol 2021.
ISSN: ESSN 2161-5063
PubMed: 33988973
DOI: 10.1021/ACSSYNBIO.1C00074
Page generated: Sun Jul 11 17:45:48 2021

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