Magnesium in PDB 7mqj: DHR1 Helicase Core

All present enzymatic activity of DHR1 Helicase Core:
3.6.4.13;

The structure of DHR1 Helicase Core, PDB code: 7mqj was solved by L.Miller, M.Chaker-Margot, S.Klinge, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.36 / 2.23
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	41.77, 130.94, 86.08, 90, 106.48, 90
R / Rfree (%)	17.9 / 22.7

The binding sites of Magnesium atom in the DHR1 Helicase Core (pdb code 7mqj). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the DHR1 Helicase Core, PDB code: 7mqj:

Magnesium binding site 1 out of 1 in the DHR1 Helicase Core


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of DHR1 Helicase Core within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1201 b:25.8 occ:1.00 O A:HOH1335 2.0 28.1 1.0 O A:HOH1338 2.0 23.5 1.0 OG1 A:THR421 2.0 32.9 1.0 O2B A:ADP1202 2.1 26.2 1.0 O A:HOH1396 2.2 27.4 1.0 O A:HOH1418 2.3 19.9 1.0 CB A:THR421 3.1 34.9 1.0 PB A:ADP1202 3.3 26.2 1.0 O1B A:ADP1202 3.6 30.2 1.0 OD2 A:ASP516 3.9 27.2 1.0 O A:SER767 3.9 28.0 1.0 N A:THR421 4.0 23.4 1.0 O1A A:ADP1202 4.0 27.0 1.0 OE1 A:GLU517 4.0 26.2 1.0 CG2 A:THR421 4.1 19.9 1.0 CA A:THR421 4.1 30.9 1.0 O3B A:ADP1202 4.2 26.8 1.0 OD1 A:ASP516 4.3 26.2 1.0 O3A A:ADP1202 4.4 28.1 1.0 O A:THR766 4.5 26.1 1.0 CG A:ASP516 4.5 26.6 1.0 O A:HOH1433 4.5 25.1 1.0 C A:SER767 4.5 29.7 1.0 CD A:GLU517 4.5 26.4 1.0 PA A:ADP1202 4.5 31.6 1.0 O A:HOH1317 4.6 28.0 1.0 CE A:LYS420 4.7 25.2 1.0 CG A:GLU517 4.8 23.2 1.0 O2A A:ADP1202 4.8 26.9 1.0 NZ A:LYS420 4.8 26.5 1.0 CB A:LYS420 4.9 22.8 1.0 CA A:SER767 4.9 30.2 1.0 OE1 A:GLN449 4.9 26.1 1.0

S.Singh, A.Vanden Broeck, L.Miller, M.Chaker-Margot, S.Klinge. Nucleolar Maturation of the Human Small Subunit Processome Science V. 373 2021.
ISSN: ESSN 1095-9203
DOI: 10.1126/SCIENCE.ABJ5338