Magnesium in PDB 7ngf: P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix
Enzymatic activity of P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix
All present enzymatic activity of P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix:
3.4.21.53;
Magnesium Binding Sites:
The binding sites of Magnesium atom in the P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix
(pdb code 7ngf). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 5 binding sites of Magnesium where determined in the
P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix, PDB code: 7ngf:
Jump to Magnesium binding site number:
1;
2;
3;
4;
5;
Magnesium binding site 1 out
of 5 in 7ngf
Go back to
Magnesium Binding Sites List in 7ngf
Magnesium binding site 1 out
of 5 in the P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1002
b:247.9
occ:1.00
|
OG1
|
A:THR530
|
2.1
|
227.4
|
1.0
|
O1B
|
A:ATP1001
|
2.1
|
248.4
|
1.0
|
O2G
|
A:ATP1001
|
2.1
|
248.4
|
1.0
|
O1G
|
A:ATP1001
|
2.6
|
248.4
|
1.0
|
HB
|
A:THR530
|
2.7
|
227.4
|
1.0
|
PG
|
A:ATP1001
|
2.8
|
248.4
|
1.0
|
CB
|
A:THR530
|
2.9
|
227.4
|
1.0
|
PB
|
A:ATP1001
|
3.2
|
248.4
|
1.0
|
O3B
|
A:ATP1001
|
3.4
|
248.4
|
1.0
|
HG21
|
A:THR530
|
3.6
|
227.4
|
1.0
|
HH22
|
B:ARG652
|
3.6
|
259.2
|
1.0
|
H
|
A:THR530
|
3.6
|
227.4
|
1.0
|
O1A
|
A:ATP1001
|
3.7
|
248.4
|
1.0
|
HZ3
|
A:LYS529
|
3.8
|
238.9
|
1.0
|
CG2
|
A:THR530
|
3.8
|
227.4
|
1.0
|
HZ1
|
A:LYS529
|
4.0
|
238.9
|
1.0
|
N
|
A:THR530
|
4.0
|
227.4
|
1.0
|
CA
|
A:THR530
|
4.1
|
227.4
|
1.0
|
O3G
|
A:ATP1001
|
4.2
|
248.4
|
1.0
|
HB2
|
A:LYS529
|
4.2
|
238.9
|
1.0
|
NH2
|
B:ARG652
|
4.2
|
259.2
|
1.0
|
PA
|
A:ATP1001
|
4.2
|
248.4
|
1.0
|
O3A
|
A:ATP1001
|
4.3
|
248.4
|
1.0
|
O2A
|
A:ATP1001
|
4.3
|
248.4
|
1.0
|
O2B
|
A:ATP1001
|
4.3
|
248.4
|
1.0
|
NZ
|
A:LYS529
|
4.3
|
238.9
|
1.0
|
HH21
|
B:ARG652
|
4.3
|
259.2
|
1.0
|
HG23
|
A:THR530
|
4.5
|
227.4
|
1.0
|
HG22
|
A:THR530
|
4.5
|
227.4
|
1.0
|
HA
|
A:THR530
|
4.5
|
227.4
|
1.0
|
HE2
|
A:LYS529
|
4.5
|
238.9
|
1.0
|
HH22
|
A:ARG710
|
4.7
|
232.2
|
1.0
|
H
|
A:GLY526
|
4.8
|
236.0
|
1.0
|
HH12
|
A:ARG710
|
4.8
|
232.2
|
1.0
|
OD2
|
A:ASP590
|
4.9
|
277.7
|
1.0
|
|
Magnesium binding site 2 out
of 5 in 7ngf
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Magnesium Binding Sites List in 7ngf
Magnesium binding site 2 out
of 5 in the P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg1002
b:267.0
occ:1.00
|
O1G
|
B:ATP1001
|
2.0
|
242.7
|
1.0
|
OG1
|
B:THR530
|
2.0
|
227.9
|
1.0
|
O1B
|
B:ATP1001
|
2.1
|
242.7
|
1.0
|
O2G
|
B:ATP1001
|
2.1
|
242.7
|
1.0
|
PG
|
B:ATP1001
|
2.4
|
242.7
|
1.0
|
HB
|
B:THR530
|
2.4
|
227.9
|
1.0
|
CB
|
B:THR530
|
2.7
|
227.9
|
1.0
|
PB
|
B:ATP1001
|
3.2
|
242.7
|
1.0
|
O3B
|
B:ATP1001
|
3.2
|
242.7
|
1.0
|
HG21
|
B:THR530
|
3.4
|
227.9
|
1.0
|
H
|
B:THR530
|
3.4
|
227.9
|
1.0
|
O1A
|
B:ATP1001
|
3.6
|
242.7
|
1.0
|
CG2
|
B:THR530
|
3.6
|
227.9
|
1.0
|
HH22
|
C:ARG652
|
3.6
|
262.6
|
1.0
|
HZ3
|
B:LYS529
|
3.7
|
228.3
|
1.0
|
O3G
|
B:ATP1001
|
3.8
|
242.7
|
1.0
|
N
|
B:THR530
|
3.9
|
227.9
|
1.0
|
CA
|
B:THR530
|
3.9
|
227.9
|
1.0
|
OE2
|
B:GLU591
|
3.9
|
269.4
|
1.0
|
O2B
|
B:ATP1001
|
4.1
|
242.7
|
1.0
|
PA
|
B:ATP1001
|
4.2
|
242.7
|
1.0
|
HB2
|
B:LYS529
|
4.2
|
228.3
|
1.0
|
O2A
|
B:ATP1001
|
4.2
|
242.7
|
1.0
|
HG23
|
B:THR530
|
4.2
|
227.9
|
1.0
|
HZ1
|
B:LYS529
|
4.3
|
228.3
|
1.0
|
HG22
|
B:THR530
|
4.3
|
227.9
|
1.0
|
O3A
|
B:ATP1001
|
4.3
|
242.7
|
1.0
|
NH2
|
C:ARG652
|
4.3
|
262.6
|
1.0
|
HH21
|
C:ARG652
|
4.4
|
262.6
|
1.0
|
NZ
|
B:LYS529
|
4.4
|
228.3
|
1.0
|
HE21
|
C:GLN615
|
4.4
|
238.0
|
1.0
|
HA
|
B:THR530
|
4.4
|
227.9
|
1.0
|
HH21
|
B:ARG710
|
4.4
|
234.7
|
1.0
|
H
|
B:GLY526
|
4.8
|
237.8
|
1.0
|
HE22
|
C:GLN615
|
4.8
|
238.0
|
1.0
|
HE2
|
B:LYS529
|
4.8
|
228.3
|
1.0
|
OD2
|
B:ASP590
|
4.8
|
264.7
|
1.0
|
NE2
|
C:GLN615
|
4.9
|
238.0
|
1.0
|
C
|
B:LYS529
|
4.9
|
228.3
|
1.0
|
HZ2
|
B:LYS529
|
4.9
|
228.3
|
1.0
|
C
|
B:THR530
|
5.0
|
227.9
|
1.0
|
H
|
B:LYS529
|
5.0
|
228.3
|
1.0
|
|
Magnesium binding site 3 out
of 5 in 7ngf
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Magnesium Binding Sites List in 7ngf
Magnesium binding site 3 out
of 5 in the P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mg1002
b:260.2
occ:1.00
|
O2G
|
D:ATP1001
|
2.0
|
266.0
|
1.0
|
O1B
|
D:ATP1001
|
2.1
|
266.0
|
1.0
|
HG1
|
D:THR530
|
2.2
|
255.7
|
1.0
|
OG1
|
D:THR530
|
2.2
|
255.7
|
1.0
|
HB
|
D:THR530
|
2.4
|
255.7
|
1.0
|
O3G
|
D:ATP1001
|
2.4
|
266.0
|
1.0
|
PG
|
D:ATP1001
|
2.5
|
266.0
|
1.0
|
CB
|
D:THR530
|
2.8
|
255.7
|
1.0
|
O3B
|
D:ATP1001
|
3.1
|
266.0
|
1.0
|
H
|
D:THR530
|
3.2
|
255.7
|
1.0
|
PB
|
D:ATP1001
|
3.3
|
266.0
|
1.0
|
O1A
|
D:ATP1001
|
3.4
|
266.0
|
1.0
|
HG21
|
D:THR530
|
3.7
|
255.7
|
1.0
|
N
|
D:THR530
|
3.7
|
255.7
|
1.0
|
CA
|
D:THR530
|
3.8
|
255.7
|
1.0
|
O1G
|
D:ATP1001
|
3.8
|
266.0
|
1.0
|
CG2
|
D:THR530
|
3.9
|
255.7
|
1.0
|
HB2
|
D:LYS529
|
4.1
|
274.4
|
1.0
|
PA
|
D:ATP1001
|
4.2
|
266.0
|
1.0
|
HA
|
D:THR530
|
4.3
|
255.7
|
1.0
|
O3A
|
D:ATP1001
|
4.3
|
266.0
|
1.0
|
O2B
|
D:ATP1001
|
4.4
|
266.0
|
1.0
|
HG22
|
D:THR530
|
4.4
|
255.7
|
1.0
|
HG23
|
D:THR530
|
4.5
|
255.7
|
1.0
|
HH12
|
D:ARG546
|
4.5
|
300.5
|
1.0
|
HZ3
|
D:LYS529
|
4.6
|
274.4
|
1.0
|
O2A
|
D:ATP1001
|
4.8
|
266.0
|
1.0
|
C
|
D:LYS529
|
4.8
|
274.4
|
1.0
|
CB
|
D:LYS529
|
4.9
|
274.4
|
1.0
|
HB3
|
D:LYS529
|
5.0
|
274.4
|
1.0
|
|
Magnesium binding site 4 out
of 5 in 7ngf
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Magnesium Binding Sites List in 7ngf
Magnesium binding site 4 out
of 5 in the P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Mg1002
b:273.2
occ:1.00
|
HG1
|
E:THR530
|
1.5
|
258.6
|
1.0
|
O1A
|
E:ATP1001
|
2.0
|
263.2
|
1.0
|
OG1
|
E:THR530
|
2.1
|
258.6
|
1.0
|
O1B
|
E:ATP1001
|
2.1
|
263.2
|
1.0
|
O2G
|
E:ATP1001
|
2.1
|
263.2
|
1.0
|
PA
|
E:ATP1001
|
2.8
|
263.2
|
1.0
|
O2A
|
E:ATP1001
|
3.0
|
263.2
|
1.0
|
PG
|
E:ATP1001
|
3.1
|
263.2
|
1.0
|
PB
|
E:ATP1001
|
3.1
|
263.2
|
1.0
|
O1G
|
E:ATP1001
|
3.3
|
263.2
|
1.0
|
CB
|
E:THR530
|
3.3
|
258.6
|
1.0
|
HB
|
E:THR530
|
3.3
|
258.6
|
1.0
|
O3A
|
E:ATP1001
|
3.3
|
263.2
|
1.0
|
H
|
E:THR530
|
3.5
|
258.6
|
1.0
|
O3B
|
E:ATP1001
|
3.5
|
263.2
|
1.0
|
HG21
|
E:THR530
|
3.8
|
258.6
|
1.0
|
CG2
|
E:THR530
|
4.1
|
258.6
|
1.0
|
N
|
E:THR530
|
4.2
|
258.6
|
1.0
|
O5'
|
E:ATP1001
|
4.2
|
263.2
|
1.0
|
CA
|
E:THR530
|
4.4
|
258.6
|
1.0
|
HG23
|
E:THR530
|
4.4
|
258.6
|
1.0
|
O3G
|
E:ATP1001
|
4.5
|
263.2
|
1.0
|
O2B
|
E:ATP1001
|
4.5
|
263.2
|
1.0
|
HB2
|
E:LYS529
|
4.6
|
263.7
|
1.0
|
HH22
|
E:ARG546
|
4.6
|
309.4
|
1.0
|
HH12
|
E:ARG546
|
4.6
|
309.4
|
1.0
|
NH2
|
E:ARG546
|
4.7
|
309.4
|
1.0
|
CZ
|
E:ARG546
|
4.7
|
309.4
|
1.0
|
NH1
|
E:ARG546
|
4.7
|
309.4
|
1.0
|
HA
|
E:THR530
|
4.8
|
258.6
|
1.0
|
H
|
E:LYS529
|
4.8
|
263.7
|
1.0
|
OD2
|
E:ASP590
|
4.8
|
328.2
|
1.0
|
HG22
|
E:THR530
|
4.9
|
258.6
|
1.0
|
HH21
|
E:ARG546
|
5.0
|
309.4
|
1.0
|
HA2
|
E:GLY526
|
5.0
|
249.9
|
1.0
|
H5'2
|
E:ATP1001
|
5.0
|
263.2
|
1.0
|
|
Magnesium binding site 5 out
of 5 in 7ngf
Go back to
Magnesium Binding Sites List in 7ngf
Magnesium binding site 5 out
of 5 in the P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 5 of P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Mg1002
b:284.4
occ:1.00
|
OG1
|
F:THR530
|
2.1
|
264.0
|
1.0
|
O1B
|
F:ATP1001
|
2.1
|
280.7
|
1.0
|
O2G
|
F:ATP1001
|
2.1
|
280.7
|
1.0
|
HB
|
F:THR530
|
2.7
|
264.0
|
1.0
|
O1G
|
F:ATP1001
|
2.8
|
280.7
|
1.0
|
PG
|
F:ATP1001
|
2.9
|
280.7
|
1.0
|
CB
|
F:THR530
|
2.9
|
264.0
|
1.0
|
PB
|
F:ATP1001
|
3.2
|
280.7
|
1.0
|
O3B
|
F:ATP1001
|
3.4
|
280.7
|
1.0
|
HG21
|
F:THR530
|
3.5
|
264.0
|
1.0
|
CG2
|
F:THR530
|
3.8
|
264.0
|
1.0
|
HH12
|
A:ARG652
|
3.8
|
288.6
|
1.0
|
H
|
F:THR530
|
3.8
|
264.0
|
1.0
|
OD2
|
F:ASP590
|
4.0
|
298.8
|
1.0
|
OE1
|
F:GLU591
|
4.0
|
313.2
|
1.0
|
HH22
|
A:ARG652
|
4.1
|
288.6
|
1.0
|
CA
|
F:THR530
|
4.1
|
264.0
|
1.0
|
HB2
|
F:LYS529
|
4.1
|
278.0
|
1.0
|
N
|
F:THR530
|
4.1
|
264.0
|
1.0
|
O2B
|
F:ATP1001
|
4.2
|
280.7
|
1.0
|
HZ3
|
F:LYS529
|
4.2
|
278.0
|
1.0
|
O3G
|
F:ATP1001
|
4.3
|
280.7
|
1.0
|
O3A
|
F:ATP1001
|
4.3
|
280.7
|
1.0
|
OD1
|
F:ASP590
|
4.4
|
298.8
|
1.0
|
O2A
|
F:ATP1001
|
4.4
|
280.7
|
1.0
|
HG22
|
F:THR530
|
4.4
|
264.0
|
1.0
|
O1A
|
F:ATP1001
|
4.4
|
280.7
|
1.0
|
HG23
|
F:THR530
|
4.4
|
264.0
|
1.0
|
HA
|
F:THR530
|
4.5
|
264.0
|
1.0
|
HZ1
|
F:LYS529
|
4.5
|
278.0
|
1.0
|
HH12
|
F:ARG710
|
4.5
|
277.9
|
1.0
|
HG1
|
F:THR638
|
4.5
|
300.1
|
1.0
|
PA
|
F:ATP1001
|
4.5
|
280.7
|
1.0
|
NH1
|
A:ARG652
|
4.6
|
288.6
|
1.0
|
CG
|
F:ASP590
|
4.6
|
298.8
|
1.0
|
HE2
|
F:LYS529
|
4.6
|
278.0
|
1.0
|
NZ
|
F:LYS529
|
4.8
|
278.0
|
1.0
|
HH11
|
F:ARG710
|
4.8
|
277.9
|
1.0
|
NH2
|
A:ARG652
|
4.8
|
288.6
|
1.0
|
HG2
|
F:GLU591
|
4.9
|
313.2
|
1.0
|
H
|
F:GLY526
|
4.9
|
270.3
|
1.0
|
HH22
|
F:ARG546
|
4.9
|
278.8
|
1.0
|
HG21
|
F:THR638
|
4.9
|
300.1
|
1.0
|
|
Reference:
I.Mohammed,
K.A.Schmitz,
N.Schenck,
T.Maier,
J.P.Abrahams.
P2C-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Endogenous Substrate Protein and in Presence of Atp/Adp Mix To Be Published.
Page generated: Thu Oct 3 01:42:23 2024
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