Magnesium in PDB 7nvr: Human Mediator with Rna Polymerase II Pre-Initiation Complex

All present enzymatic activity of Human Mediator with Rna Polymerase II Pre-Initiation Complex:
2.3.1.48; 2.7.11.22; 2.7.11.23; 2.7.7.6; 3.6.4.12;

The structure of Human Mediator with Rna Polymerase II Pre-Initiation Complex also contains other interesting chemical elements:

Iron	(Fe)	4 atoms
Zinc	(Zn)	18 atoms

The binding sites of Magnesium atom in the Human Mediator with Rna Polymerase II Pre-Initiation Complex (pdb code 7nvr). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human Mediator with Rna Polymerase II Pre-Initiation Complex, PDB code: 7nvr:

Magnesium binding site 1 out of 1 in the Human Mediator with Rna Polymerase II Pre-Initiation Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Mediator with Rna Polymerase II Pre-Initiation Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2003 b:126.1 occ:1.00 OD1 A:ASP497 2.1 60.3 1.0 OD1 A:ASP499 2.1 60.5 1.0 OD2 A:ASP495 2.2 74.2 1.0 OD1 A:ASP495 2.7 74.2 1.0 CG A:ASP495 2.8 74.2 1.0 CG A:ASP497 3.0 60.3 1.0 CG A:ASP499 3.2 60.5 1.0 OD2 A:ASP497 3.2 60.3 1.0 OD2 A:ASP499 3.5 60.5 1.0 CB A:ASP495 4.3 74.2 1.0 O A:ASP497 4.4 60.3 1.0 N A:ASP499 4.4 60.5 1.0 CB A:ASP497 4.5 60.3 1.0 CB A:ASP499 4.5 60.5 1.0 C A:ASP497 4.6 60.3 1.0 CA A:ASP499 4.8 60.5 1.0 CA A:ASP497 4.9 60.3 1.0 N A:ASP497 4.9 60.3 1.0 O A:ASP495 4.9 74.2 1.0

S.Rengachari, S.Schilbach, S.Aibara, C.Dienemann, P.Cramer. Structure of Human Mediator-Rna Polymerase II Pre-Initiation Complex. Nature 2021.
ISSN: ESSN 1476-4687
PubMed: 33902108
DOI: 10.1038/S41586-021-03555-7