Magnesium in PDB 7o0q: Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 12 (ADO_AD_066)

All present enzymatic activity of Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 12 (ADO_AD_066):
2.1.1.348;

The structure of Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 12 (ADO_AD_066), PDB code: 7o0q was solved by R.K.Bedi, A.Dolbois, A.Caflisch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.70 / 2.49
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	64.17, 64.17, 225.71, 90, 90, 120
R / Rfree (%)	21.7 / 27.8

The binding sites of Magnesium atom in the Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 12 (ADO_AD_066) (pdb code 7o0q). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 12 (ADO_AD_066), PDB code: 7o0q:

Magnesium binding site 1 out of 1 in the Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 12 (ADO_AD_066)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 12 (ADO_AD_066) within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg401 b:81.4 occ:1.00 CE1 B:HIS336 2.6 73.8 1.0 NE2 B:HIS336 2.7 76.1 1.0 CB B:HIS332 3.3 49.0 1.0 OD1 B:ASP157 3.4 86.5 1.0 OD2 B:ASP157 3.4 96.3 1.0 CG B:HIS332 3.6 58.4 1.0 ND1 B:HIS336 3.6 68.0 1.0 CD2 B:HIS332 3.8 56.9 1.0 CG B:ASP157 3.8 85.7 1.0 CD2 B:HIS336 3.9 68.5 1.0 CA B:HIS332 4.1 50.9 1.0 CG B:HIS336 4.3 69.6 1.0 ND1 B:HIS332 4.5 63.9 1.0 NE2 B:HIS332 4.7 63.1 1.0 O B:HIS332 4.7 53.0 1.0 C B:HIS332 4.7 52.4 1.0

R.K.Bedi, A.Dolbois, A.Caflisch. Crystal Structure of the Human METTL3-METTL14 Complex Bound to Compound 12 (ADO_AD_066) To Be Published.