Magnesium in PDB 7o69: Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site

Enzymatic activity of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site

All present enzymatic activity of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site:
1.16.3.1;

Protein crystallography data

The structure of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site, PDB code: 7o69 was solved by C.Pozzi, S.Ciambellotti, G.Tassone, P.Turano, S.Mangani, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 91.94 / 1.35
Space group F 4 3 2
Cell size a, b, c (Å), α, β, γ (°) 183.873, 183.873, 183.873, 90, 90, 90
R / Rfree (%) 13.4 / 15.3

Other elements in 7o69:

The structure of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site also contains other interesting chemical elements:

Chlorine (Cl) 6 atoms
Iron (Fe) 10 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site (pdb code 7o69). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site, PDB code: 7o69:
Jump to Magnesium binding site number: 1; 2; 3;

Magnesium binding site 1 out of 3 in 7o69

Go back to Magnesium Binding Sites List in 7o69
Magnesium binding site 1 out of 3 in the Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg212

b:18.0
occ:0.50
OD1 A:ASN49 1.9 4.2 0.1
O A:HOH561 2.0 20.6 0.5
O A:HOH425 2.0 19.0 0.5
O A:HOH364 2.0 16.4 0.5
O A:HOH422 2.1 15.8 0.5
O A:HOH564 2.1 22.6 0.5
O A:HOH659 2.1 25.7 0.5
CG A:ASN49 3.0 4.2 0.1
ND2 A:ASN49 3.5 4.2 0.1
O A:HOH649 3.6 37.5 1.0
OG A:SER42 3.9 12.2 0.5
O A:HOH585 4.0 25.9 1.0
OD1 A:ASN49 4.2 18.5 0.9
OG A:SER52 4.2 10.8 1.0
CB A:ASN49 4.3 4.1 0.1
NH2 A:ARG53 4.3 23.5 0.5
CB A:ASN49 4.3 14.8 0.9
O A:ASN49 4.4 9.2 1.0
NE A:ARG53 4.4 21.4 0.5
CG A:ASN49 4.4 17.3 0.9
CZ A:ARG53 4.5 21.8 0.5
CB A:SER52 4.5 10.1 1.0
O A:HOH551 4.5 23.4 0.3
CG A:ARG53 4.6 16.6 0.5
CA A:ASN49 4.7 12.7 0.9
CA A:ASN49 4.7 4.0 0.1
O A:HOH453 4.8 28.7 1.0
CB A:SER42 4.9 8.4 0.5
C A:ASN49 5.0 9.2 1.0

Magnesium binding site 2 out of 3 in 7o69

Go back to Magnesium Binding Sites List in 7o69
Magnesium binding site 2 out of 3 in the Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg213

b:21.7
occ:0.40
O A:HOH399 2.0 31.3 1.0
O A:HOH638 2.0 20.9 0.4
O A:HOH653 2.1 24.6 0.4
O A:HOH664 2.2 28.7 0.4
O A:HOH590 2.2 32.4 0.8
O A:HOH365 4.1 17.8 1.0
O A:HOH430 4.4 15.4 1.0
O A:HOH586 4.4 40.9 1.0
OE1 A:GLU17 4.5 12.7 1.0
CB A:PRO14 4.7 11.9 1.0
O A:HOH610 4.8 41.1 1.0
O A:HOH654 4.9 27.4 0.4
CG A:PRO14 4.9 13.7 1.0
O A:HOH524 4.9 34.8 1.0

Magnesium binding site 3 out of 3 in 7o69

Go back to Magnesium Binding Sites List in 7o69
Magnesium binding site 3 out of 3 in the Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 5 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg214

b:25.9
occ:0.50
O A:HOH652 1.8 32.8 0.5
O A:HOH534 2.2 25.2 0.5
O A:HOH547 2.2 13.1 0.3
O A:HOH505 2.3 32.4 1.0
O A:HOH547 3.3 11.6 0.7
NH2 A:ARG7 4.2 20.3 0.7
NE A:ARG7 4.3 17.5 0.7
NH2 A:ARG7 4.3 19.4 0.3
NE A:ARG7 4.3 18.0 0.3
O A:HOH608 4.3 28.7 0.5
O A:HOH576 4.5 35.2 1.0
CZ A:ARG7 4.7 17.7 0.7
CZ A:ARG7 4.8 18.3 0.3

Reference:

S.Ciambellotti, A.Pratesi, G.Tassone, P.Turano, S.Mangani, C.Pozzi. Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin. Chemistry 2021.
ISSN: ISSN 0947-6539
PubMed: 34343376
DOI: 10.1002/CHEM.202102270
Page generated: Fri Nov 5 15:29:41 2021

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy