Magnesium in PDB 7py4: Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited State

All present enzymatic activity of Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited State:
7.6.2.1;

The structure of Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited State also contains other interesting chemical elements:

Fluorine

(F)

3 atoms

The binding sites of Magnesium atom in the Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited State (pdb code 7py4). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited State, PDB code: 7py4:

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1301 b:41.6 occ:1.00 O A:THR456 2.1 45.9 1.0 OD2 A:ASP454 2.1 41.1 1.0 OD1 A:ASP893 2.1 46.6 1.0 F3 A:BEF1302 2.2 42.0 1.0 CG A:ASP893 3.2 46.6 1.0 CG A:ASP454 3.2 41.1 1.0 C A:THR456 3.3 45.9 1.0 OD2 A:ASP893 3.6 46.6 1.0 BE A:BEF1302 3.7 42.0 1.0 OD2 A:ASP897 3.7 44.7 1.0 O A:ASP893 3.9 46.6 1.0 OD1 A:ASP454 4.0 41.1 1.0 C A:ASP893 4.2 46.6 1.0 CB A:ASP454 4.2 41.1 1.0 CA A:THR456 4.2 45.9 1.0 N A:GLY457 4.2 39.5 1.0 N A:THR456 4.3 45.9 1.0 CA A:GLY457 4.3 39.5 1.0 N A:ASP893 4.4 46.6 1.0 CB A:THR456 4.4 45.9 1.0 CB A:ASP893 4.4 46.6 1.0 O A:ALA229 4.4 50.9 1.0 F1 A:BEF1302 4.5 42.0 1.0 OG1 A:THR458 4.5 40.1 1.0 CA A:ASP893 4.6 46.6 1.0 F2 A:BEF1302 4.7 42.0 1.0 N A:THR458 4.7 40.1 1.0 N A:GLY894 4.8 45.7 1.0 CG2 A:THR456 4.8 45.9 1.0 C A:GLY457 4.8 39.5 1.0 CG A:ASP897 4.9 44.7 1.0 OD1 A:ASN896 4.9 46.5 1.0

T.Dieudonne, S.A.Herrera, M.J.Laursen, M.Lejeune, C.Stock, K.Slimani, C.Jaxel, J.A.Lyons, C.Montigny, T.G.Pomorski, P.Nissen, G.Lenoir. Autoinhibition and Regulation By Phosphoinositides of ATP8B1, A Human Lipid Flippase Associated with Intrahepatic Cholestatic Disorders. Elife V. 11 2022.
ISSN: ESSN 2050-084X
PubMed: 35416773
DOI: 10.7554/ELIFE.75272