Magnesium in PDB 7q8b: Leishmania Major Actin Filament in Adp-Pi State

The binding sites of Magnesium atom in the Leishmania Major Actin Filament in Adp-Pi State (pdb code 7q8b). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 5 binding sites of Magnesium where determined in the Leishmania Major Actin Filament in Adp-Pi State, PDB code: 7q8b:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5;

Magnesium binding site 1 out of 5 in the Leishmania Major Actin Filament in Adp-Pi State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Leishmania Major Actin Filament in Adp-Pi State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg801 b:9.1 occ:1.00 O2B A:ADP802 2.0 8.8 1.0 O4 A:PO4803 2.2 10.8 1.0 PB A:ADP802 3.3 8.8 1.0 OE1 A:GLN137 3.4 12.7 1.0 P A:PO4803 3.7 10.8 1.0 CD A:GLN137 3.8 12.7 1.0 NE2 A:GLN137 3.8 12.7 1.0 O3B A:ADP802 3.8 8.8 1.0 OD2 A:ASP11 3.8 14.4 1.0 O2 A:PO4803 4.2 10.8 1.0 O1B A:ADP802 4.2 8.8 1.0 O3A A:ADP802 4.4 8.8 1.0 O1 A:PO4803 4.4 10.8 1.0 OD1 A:ASP11 4.5 14.4 1.0 CA A:GLY13 4.5 11.6 1.0 CG A:ASP11 4.6 14.4 1.0 OD2 A:ASP154 4.6 8.0 1.0 O3 A:PO4803 4.6 10.8 1.0 O2A A:ADP802 4.6 8.8 1.0 NZ A:LYS18 4.7 12.2 1.0 CG2 A:VAL339 4.8 12.1 1.0 CG A:GLN137 4.8 12.7 1.0

Magnesium binding site 2 out of 5 in the Leishmania Major Actin Filament in Adp-Pi State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Leishmania Major Actin Filament in Adp-Pi State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg801 b:10.2 occ:1.00 O2B B:ADP802 2.0 10.7 1.0 O4 B:PO4803 2.2 13.0 1.0 PB B:ADP802 3.3 10.7 1.0 OE1 B:GLN137 3.4 13.7 1.0 P B:PO4803 3.7 13.0 1.0 CD B:GLN137 3.8 13.7 1.0 NE2 B:GLN137 3.8 13.7 1.0 O3B B:ADP802 3.8 10.7 1.0 OD2 B:ASP11 3.8 16.6 1.0 O2 B:PO4803 4.2 13.0 1.0 O1B B:ADP802 4.2 10.7 1.0 O3A B:ADP802 4.4 10.7 1.0 O1 B:PO4803 4.4 13.0 1.0 OD1 B:ASP11 4.5 16.6 1.0 CA B:GLY13 4.5 14.4 1.0 CG B:ASP11 4.6 16.6 1.0 OD2 B:ASP154 4.6 9.0 1.0 O3 B:PO4803 4.6 13.0 1.0 O2A B:ADP802 4.6 10.7 1.0 NZ B:LYS18 4.7 14.2 1.0 CG2 B:VAL339 4.8 12.9 1.0 CG B:GLN137 4.8 13.7 1.0

Magnesium binding site 3 out of 5 in the Leishmania Major Actin Filament in Adp-Pi State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Leishmania Major Actin Filament in Adp-Pi State within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg801 b:8.0 occ:1.00 O2B C:ADP802 2.0 8.7 1.0 O4 C:PO4803 2.2 10.6 1.0 PB C:ADP802 3.3 8.7 1.0 OE1 C:GLN137 3.4 12.7 1.0 P C:PO4803 3.7 10.6 1.0 CD C:GLN137 3.8 12.7 1.0 NE2 C:GLN137 3.8 12.7 1.0 O3B C:ADP802 3.8 8.7 1.0 OD2 C:ASP11 3.8 14.0 1.0 O2 C:PO4803 4.2 10.6 1.0 O1B C:ADP802 4.2 8.7 1.0 O3A C:ADP802 4.4 8.7 1.0 O1 C:PO4803 4.4 10.6 1.0 OD1 C:ASP11 4.5 14.0 1.0 CA C:GLY13 4.5 11.2 1.0 CG C:ASP11 4.6 14.0 1.0 OD2 C:ASP154 4.6 8.1 1.0 O3 C:PO4803 4.6 10.6 1.0 O2A C:ADP802 4.6 8.7 1.0 NZ C:LYS18 4.7 11.8 1.0 CG2 C:VAL339 4.8 12.0 1.0 CG C:GLN137 4.8 12.7 1.0

Magnesium binding site 4 out of 5 in the Leishmania Major Actin Filament in Adp-Pi State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Leishmania Major Actin Filament in Adp-Pi State within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg801 b:7.7 occ:1.00 O2B D:ADP802 2.0 9.0 1.0 O4 D:PO4803 2.2 9.6 1.0 PB D:ADP802 3.3 9.0 1.0 OE1 D:GLN137 3.4 12.2 1.0 P D:PO4803 3.7 9.6 1.0 CD D:GLN137 3.8 12.2 1.0 NE2 D:GLN137 3.8 12.2 1.0 O3B D:ADP802 3.8 9.0 1.0 OD2 D:ASP11 3.8 14.7 1.0 O2 D:PO4803 4.2 9.6 1.0 O1B D:ADP802 4.2 9.0 1.0 O3A D:ADP802 4.4 9.0 1.0 O1 D:PO4803 4.4 9.6 1.0 OD1 D:ASP11 4.5 14.7 1.0 CA D:GLY13 4.5 10.9 1.0 CG D:ASP11 4.6 14.7 1.0 OD2 D:ASP154 4.6 8.1 1.0 O3 D:PO4803 4.6 9.6 1.0 O2A D:ADP802 4.6 9.0 1.0 NZ D:LYS18 4.7 12.7 1.0 CG2 D:VAL339 4.8 11.7 1.0 CG D:GLN137 4.8 12.2 1.0

Magnesium binding site 5 out of 5 in the Leishmania Major Actin Filament in Adp-Pi State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Leishmania Major Actin Filament in Adp-Pi State within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg801 b:7.1 occ:1.00 O2B E:ADP802 2.0 8.8 1.0 O4 E:PO4803 2.2 9.3 1.0 PB E:ADP802 3.3 8.8 1.0 OE1 E:GLN137 3.4 11.9 1.0 P E:PO4803 3.7 9.3 1.0 CD E:GLN137 3.8 11.9 1.0 NE2 E:GLN137 3.8 11.9 1.0 O3B E:ADP802 3.8 8.8 1.0 OD2 E:ASP11 3.8 14.7 1.0 O2 E:PO4803 4.2 9.3 1.0 O1B E:ADP802 4.2 8.8 1.0 O3A E:ADP802 4.4 8.8 1.0 O1 E:PO4803 4.4 9.3 1.0 OD1 E:ASP11 4.5 14.7 1.0 CA E:GLY13 4.5 11.3 1.0 CG E:ASP11 4.6 14.7 1.0 OD2 E:ASP154 4.6 8.2 1.0 O3 E:PO4803 4.6 9.3 1.0 O2A E:ADP802 4.6 8.8 1.0 NZ E:LYS18 4.7 13.2 1.0 CG2 E:VAL339 4.8 11.3 1.0 CG E:GLN137 4.8 11.9 1.0

T.Kotila, H.Wioland, M.Selvaraj, K.Kogan, L.Antenucci, A.Jegou, J.T.Huiskonen, G.Romet-Lemonne, P.Lappalainen. Structural Basis of Rapid Actin Dynamics in the Evolutionarily Divergent Leishmania Parasite. Nat Commun V. 13 3442 2022.
ISSN: ESSN 2041-1723
PubMed: 35705539
DOI: 10.1038/S41467-022-31068-Y