Atomistry » Magnesium » PDB 7qtm-7r3k » 7r0e
Atomistry »
  Magnesium »
    PDB 7qtm-7r3k »
      7r0e »

Magnesium in PDB 7r0e: Early Transcription Elongation State of Influenza A/H7N9 Polymerase Backtracked Due to Double Incoproation of Nucleotide Analogue T1106 and with Singly Incoporated T1106 at the +1 Position

Enzymatic activity of Early Transcription Elongation State of Influenza A/H7N9 Polymerase Backtracked Due to Double Incoproation of Nucleotide Analogue T1106 and with Singly Incoporated T1106 at the +1 Position

All present enzymatic activity of Early Transcription Elongation State of Influenza A/H7N9 Polymerase Backtracked Due to Double Incoproation of Nucleotide Analogue T1106 and with Singly Incoporated T1106 at the +1 Position:
2.7.7.48;

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Early Transcription Elongation State of Influenza A/H7N9 Polymerase Backtracked Due to Double Incoproation of Nucleotide Analogue T1106 and with Singly Incoporated T1106 at the +1 Position (pdb code 7r0e). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Early Transcription Elongation State of Influenza A/H7N9 Polymerase Backtracked Due to Double Incoproation of Nucleotide Analogue T1106 and with Singly Incoporated T1106 at the +1 Position, PDB code: 7r0e:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 7r0e

Go back to Magnesium Binding Sites List in 7r0e
Magnesium binding site 1 out of 2 in the Early Transcription Elongation State of Influenza A/H7N9 Polymerase Backtracked Due to Double Incoproation of Nucleotide Analogue T1106 and with Singly Incoporated T1106 at the +1 Position


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Early Transcription Elongation State of Influenza A/H7N9 Polymerase Backtracked Due to Double Incoproation of Nucleotide Analogue T1106 and with Singly Incoporated T1106 at the +1 Position within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg801

b:86.7
occ:1.00
OE2 A:GLU80 2.1 81.4 1.0
OD1 A:ASP108 2.6 82.3 1.0
CD A:GLU80 3.3 81.4 1.0
CG A:ASP108 3.8 82.3 1.0
NE2 A:HIS41 3.8 84.6 1.0
CG A:GLU80 4.1 81.4 1.0
OE1 A:GLU80 4.1 81.4 1.0
OE2 A:GLU119 4.1 87.0 1.0
O A:LEU106 4.1 75.6 1.0
OD2 A:ASP108 4.4 82.3 1.0
O A:PRO107 4.6 78.1 1.0
CD2 A:HIS41 4.6 84.6 1.0
CE1 A:HIS41 4.7 84.6 1.0
C A:PRO107 4.9 78.1 1.0
CB A:ASP108 5.0 82.3 1.0

Magnesium binding site 2 out of 2 in 7r0e

Go back to Magnesium Binding Sites List in 7r0e
Magnesium binding site 2 out of 2 in the Early Transcription Elongation State of Influenza A/H7N9 Polymerase Backtracked Due to Double Incoproation of Nucleotide Analogue T1106 and with Singly Incoporated T1106 at the +1 Position


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Early Transcription Elongation State of Influenza A/H7N9 Polymerase Backtracked Due to Double Incoproation of Nucleotide Analogue T1106 and with Singly Incoporated T1106 at the +1 Position within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg801

b:47.4
occ:1.00
OD1 B:ASP446 1.9 43.2 1.0
O B:HOH930 2.0 44.7 1.0
OD2 B:ASP446 2.3 43.2 1.0
CG B:ASP446 2.3 43.2 1.0
OD1 B:ASP305 2.3 45.1 1.0
O B:HOH925 2.6 43.4 1.0
O B:GLY304 3.2 42.5 1.0
CG B:ASP305 3.5 45.1 1.0
OE1 B:GLU491 3.8 41.6 1.0
CB B:ASP446 3.8 43.2 1.0
OD2 B:ASP305 4.0 45.1 1.0
C B:GLY304 4.1 42.5 1.0
OE2 B:GLU491 4.4 41.6 1.0
O B:PHE447 4.4 41.0 1.0
CD B:GLU491 4.4 41.6 1.0
CA B:ASP446 4.4 43.2 1.0
O B:GLU491 4.5 41.6 1.0
CA B:ASP305 4.5 45.1 1.0
N B:THR493 4.6 41.7 1.0
N B:PHE447 4.6 41.0 1.0
N B:ASP305 4.6 45.1 1.0
CB B:ASP305 4.6 45.1 1.0
CA B:PHE492 4.8 40.1 1.0
N B:GLY304 5.0 42.5 1.0
C B:ASP446 5.0 43.2 1.0

Reference:

T.Kouba, S.Cusack. Direct Observation of Backtracking By Influenza A and B Polymerases Upon Consecutive Incorporation of Nucleoside Analogue T1106 Cell Rep 2022.
ISSN: ESSN 2211-1247
DOI: 10.1016/J.CELREP.2022.111901
Page generated: Thu Oct 3 07:04:30 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy