Magnesium in PDB 7rex: PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites

The structure of PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites, PDB code: 7rex was solved by J.L.Jenkins, G.M.Schroeder, J.E.Wedekind, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.80 / 2.60
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	57.797, 57.797, 153.635, 90, 90, 120
R / Rfree (%)	23.2 / 27.2

The binding sites of Magnesium atom in the PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites (pdb code 7rex). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites, PDB code: 7rex:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg103 b:29.4 occ:1.00 O A:HOH201 2.0 18.6 1.0 OP1 A:C13 2.3 55.7 1.0 OP1 A:A12 2.3 40.5 1.0 P A:C13 3.7 43.2 1.0 H5'' A:A12 3.7 52.4 1.0 P A:A12 3.8 47.2 1.0 H5' A:C13 4.1 55.8 1.0 O5' A:C13 4.1 44.1 1.0 O5' A:A12 4.3 46.4 1.0 H6 A:C13 4.4 54.0 1.0 C5' A:A12 4.5 43.7 1.0 O3' A:A11 4.6 47.8 1.0 O3' A:A12 4.6 40.5 1.0 C5' A:C13 4.7 46.5 1.0 OP2 A:C13 4.7 50.5 1.0 OP2 A:A12 4.8 44.1 1.0

Magnesium binding site 2 out of 4 in the PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg104 b:51.3 occ:1.00 OP1 A:A11 4.2 49.0 1.0 O3' A:C10 4.8 55.7 1.0

Magnesium binding site 3 out of 4 in the PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg105 b:47.3 occ:1.00 OP2 A:G5 3.8 63.1 1.0 OP1 A:C14 4.3 42.8 1.0 O3' A:C13 4.8 47.5 1.0 P A:G5 5.0 60.9 1.0

Magnesium binding site 4 out of 4 in the PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of PREQ1-1 (Type-1) Riboswitch in Complex with Tandem Stacked Metabolites within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg103 b:60.9 occ:1.00 OP1 C:A20 2.6 127.3 1.0 O3' C:C19 2.8 113.7 1.0 H5'' C:C19 2.8 136.7 1.0 P C:A20 2.8 124.1 1.0 OP2 C:A20 3.0 118.9 1.0 C5' C:C19 3.6 113.9 1.0 C3' C:C19 3.7 107.7 1.0 H3' C:C19 3.7 129.3 1.0 OP1 C:C19 3.8 117.0 1.0 C4' C:C19 4.0 112.0 1.0 O5' C:C19 4.1 113.4 1.0 H4' C:C19 4.1 134.4 1.0 H5' C:C19 4.3 136.7 1.0 O5' C:A20 4.4 122.5 1.0 P C:C19 4.6 114.3 1.0 H5' C:A20 5.0 153.8 1.0

G.M.Schroeder, C.E.Cavendar, M.E.Blau, J.L.Jenkins, D.H.Mathews, J.E.Wedekind. A Small Rna That Cooperatively Senses Two Stacked Metabolites in One Pocket For Gene Control Nat Commun 2021.
ISSN: ESSN 2041-1723