Magnesium in PDB 7sxo: Yeast Lon (PIM1) with Endogenous Substrate

All present enzymatic activity of Yeast Lon (PIM1) with Endogenous Substrate:
3.4.21.53;

The binding sites of Magnesium atom in the Yeast Lon (PIM1) with Endogenous Substrate (pdb code 7sxo). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Yeast Lon (PIM1) with Endogenous Substrate, PDB code: 7sxo:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Yeast Lon (PIM1) with Endogenous Substrate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Yeast Lon (PIM1) with Endogenous Substrate within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1201 b:45.2 occ:1.00 OG A:SER657 2.5 48.4 1.0 CG F:GLU719 2.9 40.0 1.0 CB F:GLU719 3.0 40.0 1.0 N A:GLY659 3.3 43.8 1.0 CA A:GLY659 3.4 43.8 1.0 CB A:SER657 3.6 48.4 1.0 N A:GLY660 3.8 57.7 1.0 CD F:GLU719 4.0 40.0 1.0 C A:GLY659 4.0 43.8 1.0 O F:ALA715 4.2 43.5 1.0 OE1 F:GLU719 4.3 40.0 1.0 CA F:GLU719 4.4 40.0 1.0 NZ F:LYS668 4.5 49.2 1.0 CE F:LYS668 4.5 49.2 1.0 C A:SER657 4.5 48.4 1.0 CA F:ALA716 4.5 38.0 1.0 C A:VAL658 4.6 45.4 1.0 N A:VAL658 4.7 45.4 1.0 CA A:SER657 4.7 48.4 1.0 O A:SER657 4.7 48.4 1.0 C F:ALA715 4.8 43.5 1.0 OE2 F:GLU719 4.9 40.0 1.0 N F:GLU719 4.9 40.0 1.0 N F:ALA716 4.9 38.0 1.0 CA A:GLY660 5.0 57.7 1.0

Magnesium binding site 2 out of 4 in the Yeast Lon (PIM1) with Endogenous Substrate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Yeast Lon (PIM1) with Endogenous Substrate within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg1201 b:44.1 occ:1.00 OD1 D:ASN750 2.1 49.1 1.0 CE D:LYS638 2.8 46.7 1.0 O2G D:ATP1200 2.8 54.8 1.0 CG D:ASN750 2.9 49.1 1.0 NZ D:LYS638 3.1 46.7 1.0 ND2 D:ASN750 3.4 49.1 1.0 CG2 D:THR748 3.9 47.8 1.0 O D:ALA749 4.0 45.4 1.0 C D:ALA749 4.0 45.4 1.0 PG D:ATP1200 4.1 54.8 1.0 N D:ASN750 4.1 49.1 1.0 CD D:LYS638 4.1 46.7 1.0 CB D:ASN750 4.1 49.1 1.0 O D:GLY632 4.3 39.7 1.0 CA D:ASN750 4.3 49.1 1.0 OE2 D:GLU700 4.4 57.2 1.0 O3B D:ATP1200 4.4 54.8 1.0 O3G D:ATP1200 4.5 54.8 1.0 CA D:ALA749 4.6 45.4 1.0 O1B D:ATP1200 4.6 54.8 1.0 N D:ALA749 4.7 45.4 1.0 OE1 D:GLU700 4.7 57.2 1.0 CG D:LYS638 4.7 46.7 1.0 CD D:GLU700 4.9 57.2 1.0

Magnesium binding site 3 out of 4 in the Yeast Lon (PIM1) with Endogenous Substrate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Yeast Lon (PIM1) with Endogenous Substrate within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg1202 b:27.4 occ:1.00 OG E:SER787 3.2 30.4 1.0 CB E:SER787 3.7 30.4 1.0 CE E:LYS790 4.6 35.7 1.0 CA E:SER787 4.6 30.4 1.0 NZ E:LYS790 4.9 35.7 1.0

Magnesium binding site 4 out of 4 in the Yeast Lon (PIM1) with Endogenous Substrate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Yeast Lon (PIM1) with Endogenous Substrate within 5.0Å range:

J.Yang, A.S.Song, R.L.Wiseman, G.C.Lander. Cryo-Em Structure of Hexameric Yeast Lon Protease (PIM1) Highlights the Importance of Conserved Structural Elements. J.Biol.Chem. V. 298 01694 2022.
ISSN: ESSN 1083-351X
PubMed: 35143841
DOI: 10.1016/J.JBC.2022.101694