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Atomistry » Magnesium » PDB 7thj-7to2 » 7tlg | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 7thj-7to2 » 7tlg » |
Magnesium in PDB 7tlg: Crystal Structure of Small Molecule Beta-Lactone 5 Covalently Bound to K-Ras(G12S)Enzymatic activity of Crystal Structure of Small Molecule Beta-Lactone 5 Covalently Bound to K-Ras(G12S)
All present enzymatic activity of Crystal Structure of Small Molecule Beta-Lactone 5 Covalently Bound to K-Ras(G12S):
3.6.5.2; Protein crystallography data
The structure of Crystal Structure of Small Molecule Beta-Lactone 5 Covalently Bound to K-Ras(G12S), PDB code: 7tlg
was solved by
Z.Ziyang,
K.Z.Guiley,
K.M.Shokat,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7tlg:
The structure of Crystal Structure of Small Molecule Beta-Lactone 5 Covalently Bound to K-Ras(G12S) also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Small Molecule Beta-Lactone 5 Covalently Bound to K-Ras(G12S)
(pdb code 7tlg). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Small Molecule Beta-Lactone 5 Covalently Bound to K-Ras(G12S), PDB code: 7tlg: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 7tlgGo back to Magnesium Binding Sites List in 7tlg
Magnesium binding site 1 out
of 2 in the Crystal Structure of Small Molecule Beta-Lactone 5 Covalently Bound to K-Ras(G12S)
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 7tlgGo back to Magnesium Binding Sites List in 7tlg
Magnesium binding site 2 out
of 2 in the Crystal Structure of Small Molecule Beta-Lactone 5 Covalently Bound to K-Ras(G12S)
Mono view Stereo pair view
Reference:
Z.Zhang,
K.Z.Guiley,
K.M.Shokat.
Chemical Acylation of An Acquired Serine Suppresses Oncogenic Signaling of K-Ras(G12S). Nat.Chem.Biol. V. 18 1177 2022.
Page generated: Thu Oct 3 09:20:57 2024
ISSN: ESSN 1552-4469 PubMed: 35864332 DOI: 10.1038/S41589-022-01065-9 |
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