Magnesium in PDB 7u22: Mycobacterium Tuberculosis Rna Polymerase Sigma A Holoenzyme Open Promoter Complex Containing Umn-7
Enzymatic activity of Mycobacterium Tuberculosis Rna Polymerase Sigma A Holoenzyme Open Promoter Complex Containing Umn-7
All present enzymatic activity of Mycobacterium Tuberculosis Rna Polymerase Sigma A Holoenzyme Open Promoter Complex Containing Umn-7:
2.7.7.6;
2.7.7.6;
Protein crystallography data
The structure of Mycobacterium Tuberculosis Rna Polymerase Sigma A Holoenzyme Open Promoter Complex Containing Umn-7, PDB code: 7u22
was solved by
V.Molodtsov,
R.H.Ebright,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 48.30 / 3.87 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 149.482, 161.445, 196.603, 90, 90, 90 |
| R / Rfree (%) | 24 / 27.8 |
Other elements in 7u22:
The structure of Mycobacterium Tuberculosis Rna Polymerase Sigma A Holoenzyme Open Promoter Complex Containing Umn-7 also contains other interesting chemical elements:
| Zinc | (Zn) | 2 atoms |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Mycobacterium Tuberculosis Rna Polymerase Sigma A Holoenzyme Open Promoter Complex Containing Umn-7
(pdb code 7u22). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Mycobacterium Tuberculosis Rna Polymerase Sigma A Holoenzyme Open Promoter Complex Containing Umn-7, PDB code: 7u22:
In total only one binding site of Magnesium was determined in the Mycobacterium Tuberculosis Rna Polymerase Sigma A Holoenzyme Open Promoter Complex Containing Umn-7, PDB code: 7u22:
Magnesium binding site 1 out of 1 in 7u22
Go back to
Magnesium Binding Sites List in 7u22
Magnesium binding site 1 out
of 1 in the Mycobacterium Tuberculosis Rna Polymerase Sigma A Holoenzyme Open Promoter Complex Containing Umn-7
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Mycobacterium Tuberculosis Rna Polymerase Sigma A Holoenzyme Open Promoter Complex Containing Umn-7 within 5.0Å range:
|
Reference:
T.Lan,
U.S.Ganapathy,
S.Sharma,
Y.M.Ahn,
M.Zimmerman,
V.Molodtsov,
P.Hegde,
M.Gengenbacher,
R.H.Ebright,
V.Dartois,
J.S.Freundlich,
T.Dick,
C.C.Aldrich.
Redesign of Rifamycin Antibiotics to Overcome Adp-Ribosylation-Mediated Resistance. Angew.Chem.Int.Ed.Engl. V. 61 11498 2022.
ISSN: ESSN 1521-3773
PubMed: 36222275
DOI: 10.1002/ANIE.202211498
Page generated: Thu Apr 6 23:33:45 2023
ISSN: ESSN 1521-3773
PubMed: 36222275
DOI: 10.1002/ANIE.202211498
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