Magnesium in PDB 7uob: Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State

All present enzymatic activity of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State:
2.7.7.48;

The structure of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Magnesium atom in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State (pdb code 7uob). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State, PDB code: 7uob:
Jump to Magnesium binding site number: 1; 2; 3;

Magnesium binding site 1 out of 3 in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1003 b:11.2 occ:1.00 OD1 A:ASP618 2.5 9.0 1.0 O P:HOH210 2.7 11.2 1.0 OD2 A:ASP761 2.8 6.2 1.0 OD1 A:ASP760 2.8 6.6 1.0 O1A A:GTP1006 3.0 7.8 1.0 C3' P:L2B101 3.2 13.7 1.0 CG A:ASP618 3.4 9.0 1.0 OD2 A:ASP618 3.5 9.0 1.0 CG A:ASP760 3.6 6.6 1.0 C5' P:L2B101 3.7 13.7 1.0 OD2 A:ASP760 3.7 6.6 1.0 CG A:ASP761 3.8 6.2 1.0 C4' P:L2B101 3.8 13.7 1.0 O5' P:L2B101 3.9 13.7 1.0 PA A:GTP1006 4.1 7.8 1.0 MG A:MG1004 4.3 4.5 1.0 OD1 A:ASP761 4.4 6.2 1.0 O5' A:GTP1006 4.4 7.8 1.0 C5' A:GTP1006 4.5 7.8 1.0 O A:HOH1285 4.5 12.6 1.0 O2A A:GTP1006 4.5 7.8 1.0 O A:HOH1122 4.5 8.0 1.0 C2' P:L2B101 4.6 13.7 1.0 CB A:ASP761 4.6 6.2 1.0 O A:ASP760 4.7 6.6 1.0 C A:ASP760 4.8 6.6 1.0 CB A:ASP618 4.8 9.0 1.0 OP1 P:L2B101 4.8 13.7 1.0 N A:ASP761 4.9 6.2 1.0 O2' P:L2B101 5.0 13.7 1.0

Magnesium binding site 2 out of 3 in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1004 b:4.5 occ:1.00 O1A A:GTP1006 2.2 7.8 1.0 O2G A:GTP1006 2.2 7.8 1.0 O2B A:GTP1006 2.2 7.8 1.0 O A:TYR619 2.3 7.4 1.0 OD2 A:ASP760 2.6 6.6 1.0 OD2 A:ASP618 2.9 9.0 1.0 PA A:GTP1006 3.3 7.8 1.0 PB A:GTP1006 3.3 7.8 1.0 C A:TYR619 3.5 7.4 1.0 PG A:GTP1006 3.6 7.8 1.0 O3A A:GTP1006 3.6 7.8 1.0 CG A:ASP618 3.7 9.0 1.0 CG A:ASP760 3.8 6.6 1.0 O3B A:GTP1006 3.8 7.8 1.0 N A:TYR619 4.1 7.4 1.0 C5' A:GTP1006 4.1 7.8 1.0 OD1 A:ASP618 4.1 9.0 1.0 MG A:MG1003 4.3 11.2 1.0 O5' A:GTP1006 4.3 7.8 1.0 CA A:TYR619 4.3 7.4 1.0 O A:HOH1285 4.3 12.6 1.0 O2A A:GTP1006 4.4 7.8 1.0 O3G A:GTP1006 4.4 7.8 1.0 OD1 A:ASP760 4.4 6.6 1.0 N A:PRO620 4.4 9.1 1.0 N A:LYS621 4.5 8.1 1.0 C A:ASP618 4.5 9.0 1.0 CA A:PRO620 4.5 9.1 1.0 O1G A:GTP1006 4.5 7.8 1.0 O1B A:GTP1006 4.6 7.8 1.0 CB A:TYR619 4.7 7.4 1.0 CB A:ASP618 4.8 9.0 1.0 N A:CYS622 4.8 7.8 1.0 CE A:LYS798 4.9 12.6 1.0 C A:PRO620 4.9 9.1 1.0 CB A:CYS622 4.9 7.8 1.0 O A:ASP618 4.9 9.0 1.0 CB A:ASP760 5.0 6.6 1.0

Magnesium binding site 3 out of 3 in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1005 b:10.3 occ:1.00 O2A A:GTP1007 2.2 18.7 1.0 O1B A:GTP1007 2.4 18.7 1.0 ND2 A:ASN209 2.4 8.7 1.0 O3' A:GTP1007 2.9 18.7 1.0 OD2 A:ASP208 3.4 7.4 1.0 CG A:ASN209 3.5 8.7 1.0 PA A:GTP1007 3.6 18.7 1.0 OD2 A:ASP218 3.6 14.0 1.0 PB A:GTP1007 3.7 18.7 1.0 O A:ASP208 3.9 7.4 1.0 OD1 A:ASN209 3.9 8.7 1.0 C3' A:GTP1007 4.0 18.7 1.0 O3A A:GTP1007 4.1 18.7 1.0 C4' A:GTP1007 4.2 18.7 1.0 CE1 A:PHE35 4.3 11.4 1.0 CG A:ASP208 4.3 7.4 1.0 C A:ASP208 4.3 7.4 1.0 O2B A:GTP1007 4.4 18.7 1.0 CG A:ASP218 4.5 14.0 1.0 O5' A:GTP1007 4.5 18.7 1.0 CB A:ASP208 4.6 7.4 1.0 CA A:ASN209 4.6 8.7 1.0 N A:ASN209 4.6 8.7 1.0 CB A:ASN209 4.6 8.7 1.0 CD1 A:PHE35 4.6 11.4 1.0 C5' A:GTP1007 4.6 18.7 1.0 O1A A:GTP1007 4.6 18.7 1.0 O3B A:GTP1007 4.8 18.7 1.0 CE1 A:TYR217 4.9 11.3 1.0 CB A:ASP218 5.0 14.0 1.0

B.F.Malone, S.A.Darst. Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre-Catalytic State To Be Published.