Magnesium in PDB 7uob: Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State
Enzymatic activity of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State
All present enzymatic activity of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State:
2.7.7.48;
Other elements in 7uob:
The structure of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State
(pdb code 7uob). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the
Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State, PDB code: 7uob:
Jump to Magnesium binding site number:
1;
2;
3;
Magnesium binding site 1 out
of 3 in 7uob
Go back to
Magnesium Binding Sites List in 7uob
Magnesium binding site 1 out
of 3 in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1003
b:11.2
occ:1.00
|
OD1
|
A:ASP618
|
2.5
|
9.0
|
1.0
|
O
|
P:HOH210
|
2.7
|
11.2
|
1.0
|
OD2
|
A:ASP761
|
2.8
|
6.2
|
1.0
|
OD1
|
A:ASP760
|
2.8
|
6.6
|
1.0
|
O1A
|
A:GTP1006
|
3.0
|
7.8
|
1.0
|
C3'
|
P:L2B101
|
3.2
|
13.7
|
1.0
|
CG
|
A:ASP618
|
3.4
|
9.0
|
1.0
|
OD2
|
A:ASP618
|
3.5
|
9.0
|
1.0
|
CG
|
A:ASP760
|
3.6
|
6.6
|
1.0
|
C5'
|
P:L2B101
|
3.7
|
13.7
|
1.0
|
OD2
|
A:ASP760
|
3.7
|
6.6
|
1.0
|
CG
|
A:ASP761
|
3.8
|
6.2
|
1.0
|
C4'
|
P:L2B101
|
3.8
|
13.7
|
1.0
|
O5'
|
P:L2B101
|
3.9
|
13.7
|
1.0
|
PA
|
A:GTP1006
|
4.1
|
7.8
|
1.0
|
MG
|
A:MG1004
|
4.3
|
4.5
|
1.0
|
OD1
|
A:ASP761
|
4.4
|
6.2
|
1.0
|
O5'
|
A:GTP1006
|
4.4
|
7.8
|
1.0
|
C5'
|
A:GTP1006
|
4.5
|
7.8
|
1.0
|
O
|
A:HOH1285
|
4.5
|
12.6
|
1.0
|
O2A
|
A:GTP1006
|
4.5
|
7.8
|
1.0
|
O
|
A:HOH1122
|
4.5
|
8.0
|
1.0
|
C2'
|
P:L2B101
|
4.6
|
13.7
|
1.0
|
CB
|
A:ASP761
|
4.6
|
6.2
|
1.0
|
O
|
A:ASP760
|
4.7
|
6.6
|
1.0
|
C
|
A:ASP760
|
4.8
|
6.6
|
1.0
|
CB
|
A:ASP618
|
4.8
|
9.0
|
1.0
|
OP1
|
P:L2B101
|
4.8
|
13.7
|
1.0
|
N
|
A:ASP761
|
4.9
|
6.2
|
1.0
|
O2'
|
P:L2B101
|
5.0
|
13.7
|
1.0
|
|
Magnesium binding site 2 out
of 3 in 7uob
Go back to
Magnesium Binding Sites List in 7uob
Magnesium binding site 2 out
of 3 in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1004
b:4.5
occ:1.00
|
O1A
|
A:GTP1006
|
2.2
|
7.8
|
1.0
|
O2G
|
A:GTP1006
|
2.2
|
7.8
|
1.0
|
O2B
|
A:GTP1006
|
2.2
|
7.8
|
1.0
|
O
|
A:TYR619
|
2.3
|
7.4
|
1.0
|
OD2
|
A:ASP760
|
2.6
|
6.6
|
1.0
|
OD2
|
A:ASP618
|
2.9
|
9.0
|
1.0
|
PA
|
A:GTP1006
|
3.3
|
7.8
|
1.0
|
PB
|
A:GTP1006
|
3.3
|
7.8
|
1.0
|
C
|
A:TYR619
|
3.5
|
7.4
|
1.0
|
PG
|
A:GTP1006
|
3.6
|
7.8
|
1.0
|
O3A
|
A:GTP1006
|
3.6
|
7.8
|
1.0
|
CG
|
A:ASP618
|
3.7
|
9.0
|
1.0
|
CG
|
A:ASP760
|
3.8
|
6.6
|
1.0
|
O3B
|
A:GTP1006
|
3.8
|
7.8
|
1.0
|
N
|
A:TYR619
|
4.1
|
7.4
|
1.0
|
C5'
|
A:GTP1006
|
4.1
|
7.8
|
1.0
|
OD1
|
A:ASP618
|
4.1
|
9.0
|
1.0
|
MG
|
A:MG1003
|
4.3
|
11.2
|
1.0
|
O5'
|
A:GTP1006
|
4.3
|
7.8
|
1.0
|
CA
|
A:TYR619
|
4.3
|
7.4
|
1.0
|
O
|
A:HOH1285
|
4.3
|
12.6
|
1.0
|
O2A
|
A:GTP1006
|
4.4
|
7.8
|
1.0
|
O3G
|
A:GTP1006
|
4.4
|
7.8
|
1.0
|
OD1
|
A:ASP760
|
4.4
|
6.6
|
1.0
|
N
|
A:PRO620
|
4.4
|
9.1
|
1.0
|
N
|
A:LYS621
|
4.5
|
8.1
|
1.0
|
C
|
A:ASP618
|
4.5
|
9.0
|
1.0
|
CA
|
A:PRO620
|
4.5
|
9.1
|
1.0
|
O1G
|
A:GTP1006
|
4.5
|
7.8
|
1.0
|
O1B
|
A:GTP1006
|
4.6
|
7.8
|
1.0
|
CB
|
A:TYR619
|
4.7
|
7.4
|
1.0
|
CB
|
A:ASP618
|
4.8
|
9.0
|
1.0
|
N
|
A:CYS622
|
4.8
|
7.8
|
1.0
|
CE
|
A:LYS798
|
4.9
|
12.6
|
1.0
|
C
|
A:PRO620
|
4.9
|
9.1
|
1.0
|
CB
|
A:CYS622
|
4.9
|
7.8
|
1.0
|
O
|
A:ASP618
|
4.9
|
9.0
|
1.0
|
CB
|
A:ASP760
|
5.0
|
6.6
|
1.0
|
|
Magnesium binding site 3 out
of 3 in 7uob
Go back to
Magnesium Binding Sites List in 7uob
Magnesium binding site 3 out
of 3 in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1005
b:10.3
occ:1.00
|
O2A
|
A:GTP1007
|
2.2
|
18.7
|
1.0
|
O1B
|
A:GTP1007
|
2.4
|
18.7
|
1.0
|
ND2
|
A:ASN209
|
2.4
|
8.7
|
1.0
|
O3'
|
A:GTP1007
|
2.9
|
18.7
|
1.0
|
OD2
|
A:ASP208
|
3.4
|
7.4
|
1.0
|
CG
|
A:ASN209
|
3.5
|
8.7
|
1.0
|
PA
|
A:GTP1007
|
3.6
|
18.7
|
1.0
|
OD2
|
A:ASP218
|
3.6
|
14.0
|
1.0
|
PB
|
A:GTP1007
|
3.7
|
18.7
|
1.0
|
O
|
A:ASP208
|
3.9
|
7.4
|
1.0
|
OD1
|
A:ASN209
|
3.9
|
8.7
|
1.0
|
C3'
|
A:GTP1007
|
4.0
|
18.7
|
1.0
|
O3A
|
A:GTP1007
|
4.1
|
18.7
|
1.0
|
C4'
|
A:GTP1007
|
4.2
|
18.7
|
1.0
|
CE1
|
A:PHE35
|
4.3
|
11.4
|
1.0
|
CG
|
A:ASP208
|
4.3
|
7.4
|
1.0
|
C
|
A:ASP208
|
4.3
|
7.4
|
1.0
|
O2B
|
A:GTP1007
|
4.4
|
18.7
|
1.0
|
CG
|
A:ASP218
|
4.5
|
14.0
|
1.0
|
O5'
|
A:GTP1007
|
4.5
|
18.7
|
1.0
|
CB
|
A:ASP208
|
4.6
|
7.4
|
1.0
|
CA
|
A:ASN209
|
4.6
|
8.7
|
1.0
|
N
|
A:ASN209
|
4.6
|
8.7
|
1.0
|
CB
|
A:ASN209
|
4.6
|
8.7
|
1.0
|
CD1
|
A:PHE35
|
4.6
|
11.4
|
1.0
|
C5'
|
A:GTP1007
|
4.6
|
18.7
|
1.0
|
O1A
|
A:GTP1007
|
4.6
|
18.7
|
1.0
|
O3B
|
A:GTP1007
|
4.8
|
18.7
|
1.0
|
CE1
|
A:TYR217
|
4.9
|
11.3
|
1.0
|
CB
|
A:ASP218
|
5.0
|
14.0
|
1.0
|
|
Reference:
B.F.Malone,
S.A.Darst.
Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre-Catalytic State To Be Published.
Page generated: Thu Oct 3 10:09:22 2024
|