Magnesium in PDB 7uoe: Sars-Cov-2 Replication-Transcription Complex Bound to Ctp, in A Pre- Catalytic State

All present enzymatic activity of Sars-Cov-2 Replication-Transcription Complex Bound to Ctp, in A Pre- Catalytic State:
2.7.7.48;

The structure of Sars-Cov-2 Replication-Transcription Complex Bound to Ctp, in A Pre- Catalytic State also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Magnesium atom in the Sars-Cov-2 Replication-Transcription Complex Bound to Ctp, in A Pre- Catalytic State (pdb code 7uoe). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Sars-Cov-2 Replication-Transcription Complex Bound to Ctp, in A Pre- Catalytic State, PDB code: 7uoe:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Sars-Cov-2 Replication-Transcription Complex Bound to Ctp, in A Pre- Catalytic State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Sars-Cov-2 Replication-Transcription Complex Bound to Ctp, in A Pre- Catalytic State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1003 b:56.5 occ:1.00 O A:HOH1270 2.1 35.8 1.0 OD2 A:ASP761 2.3 56.7 1.0 OD1 A:ASP618 2.8 50.3 1.0 OD1 A:ASP760 2.9 55.3 1.0 OD2 A:ASP618 3.1 54.0 1.0 CG A:ASP618 3.3 47.8 1.0 CG A:ASP761 3.4 51.9 1.0 OD2 A:ASP760 3.6 46.8 1.0 CG A:ASP760 3.6 52.5 1.0 O2A A:CTP1005 3.7 49.9 1.0 C3' P:L2B101 3.9 37.1 1.0 OD1 A:ASP761 4.0 53.6 1.0 O5' P:L2B101 4.0 44.3 1.0 C5' P:L2B101 4.1 44.0 1.0 OP1 P:L2B101 4.4 44.8 1.0 CB A:ASP761 4.5 36.5 1.0 O1A A:CTP1005 4.5 54.7 1.0 PA A:CTP1005 4.5 62.3 1.0 C4' P:L2B101 4.6 45.2 1.0 O5' A:CTP1005 4.6 56.9 1.0 O A:HOH1197 4.7 56.9 1.0 MG A:MG1004 4.7 42.0 1.0 N A:ASP761 4.8 41.1 1.0 CB A:ASP618 4.8 47.0 1.0 CA A:ASP761 4.9 39.6 1.0 C A:ASP760 5.0 44.0 1.0 P P:L2B101 5.0 40.7 1.0

Magnesium binding site 2 out of 2 in the Sars-Cov-2 Replication-Transcription Complex Bound to Ctp, in A Pre- Catalytic State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Sars-Cov-2 Replication-Transcription Complex Bound to Ctp, in A Pre- Catalytic State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1004 b:42.0 occ:1.00 O A:TYR619 2.2 47.9 1.0 O2G A:CTP1005 2.2 51.6 1.0 O1B A:CTP1005 2.3 55.2 1.0 O2A A:CTP1005 2.4 49.9 1.0 OD2 A:ASP618 2.6 54.0 1.0 OD2 A:ASP760 2.7 46.8 1.0 C A:TYR619 3.3 47.6 1.0 CG A:ASP618 3.4 47.8 1.0 PB A:CTP1005 3.6 62.5 1.0 PG A:CTP1005 3.6 73.9 1.0 N A:TYR619 3.7 45.4 1.0 PA A:CTP1005 3.7 62.3 1.0 CG A:ASP760 3.9 52.5 1.0 O3B A:CTP1005 4.0 53.2 1.0 CA A:TYR619 4.0 42.6 1.0 O3A A:CTP1005 4.1 44.6 1.0 CB A:ASP618 4.1 47.0 1.0 NZ A:LYS798 4.2 51.4 1.0 OD1 A:ASP618 4.2 50.3 1.0 C A:ASP618 4.3 46.9 1.0 N A:PRO620 4.3 42.5 1.0 C5' A:CTP1005 4.3 49.3 1.0 CB A:CYS622 4.3 42.1 1.0 O3G A:CTP1005 4.4 52.6 1.0 CB A:TYR619 4.5 40.1 1.0 O1G A:CTP1005 4.5 53.6 1.0 CA A:PRO620 4.5 43.9 1.0 O5' A:CTP1005 4.5 56.9 1.0 N A:CYS622 4.6 49.8 1.0 OD1 A:ASP760 4.6 55.3 1.0 N A:LYS621 4.6 48.0 1.0 CA A:ASP618 4.7 52.1 1.0 MG A:MG1003 4.7 56.5 1.0 CE A:LYS798 4.7 54.6 1.0 O2B A:CTP1005 4.7 53.0 1.0 O1A A:CTP1005 4.7 54.7 1.0 C A:PRO620 4.8 45.9 1.0 CB A:ASP760 4.9 48.4 1.0

B.F.Malone, S.A.Darst. Sars-Cov-2 Replication-Transcription Complex Bound to Ctp, in A Pre-Catalytic State To Be Published.