Magnesium in PDB 7z38: Structure of the RAF1-HSP90-CDC37 Complex (Rhc-I)

All present enzymatic activity of Structure of the RAF1-HSP90-CDC37 Complex (Rhc-I):
2.7.11.1;

The binding sites of Magnesium atom in the Structure of the RAF1-HSP90-CDC37 Complex (Rhc-I) (pdb code 7z38). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of the RAF1-HSP90-CDC37 Complex (Rhc-I), PDB code: 7z38:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of the RAF1-HSP90-CDC37 Complex (Rhc-I)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the RAF1-HSP90-CDC37 Complex (Rhc-I) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg802 b:5.5 occ:1.00 O3B A:ATP801 2.9 47.6 1.0 O2B A:ATP801 3.1 46.4 1.0 O A:ILE126 3.1 32.9 1.0 OD1 A:ASN46 3.3 16.7 1.0 O2G A:ATP801 3.3 32.2 1.0 PB A:ATP801 3.7 30.4 1.0 O2A A:ATP801 3.8 46.5 1.0 PG A:ATP801 3.8 12.3 1.0 CB A:SER45 3.9 9.9 1.0 CG A:ASN46 4.0 19.1 1.0 OD2 A:ASP49 4.0 27.3 1.0 N A:ASN46 4.2 7.9 1.0 O A:GLU42 4.2 31.6 1.0 C A:ILE126 4.3 25.2 1.0 OE1 A:GLU42 4.3 27.9 1.0 CA A:GLY127 4.3 29.6 1.0 C A:SER45 4.4 14.4 1.0 ND2 A:ASN46 4.5 23.3 1.0 O3A A:ATP801 4.6 32.0 1.0 CA A:ASN46 4.6 17.7 1.0 O A:SER45 4.7 30.1 1.0 O3G A:ATP801 4.7 39.3 1.0 O1B A:ATP801 4.8 44.1 1.0 CA A:SER45 4.8 11.1 1.0 N A:GLY127 4.8 26.3 1.0 O1G A:ATP801 4.8 41.4 1.0 CB A:ASN46 4.9 19.1 1.0 PA A:ATP801 4.9 15.7 1.0 OG A:SER45 4.9 17.4 1.0

Magnesium binding site 2 out of 2 in the Structure of the RAF1-HSP90-CDC37 Complex (Rhc-I)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the RAF1-HSP90-CDC37 Complex (Rhc-I) within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg802 b:13.3 occ:1.00 OD1 B:ASN46 2.1 17.6 1.0 O2G B:ATP801 2.4 19.7 1.0 O2B B:ATP801 2.5 29.2 1.0 CG B:ASN46 3.2 12.6 1.0 O1A B:ATP801 3.2 19.9 1.0 O B:GLU42 3.7 36.4 1.0 PB B:ATP801 3.8 25.6 1.0 PG B:ATP801 3.8 0.0 1.0 OE1 B:GLU42 3.8 26.2 1.0 ND2 B:ASN46 3.9 15.1 1.0 N B:ASN46 3.9 4.6 1.0 CB B:SER45 3.9 12.8 1.0 O3B B:ATP801 4.0 17.2 1.0 CA B:ASN46 4.2 10.7 1.0 CB B:ASN46 4.3 8.2 1.0 C B:SER45 4.3 10.3 1.0 O B:ILE126 4.3 27.5 1.0 PA B:ATP801 4.3 5.6 1.0 O3A B:ATP801 4.4 10.1 1.0 OD2 B:ASP49 4.5 21.4 1.0 O1G B:ATP801 4.6 17.9 1.0 C B:GLU42 4.6 18.5 1.0 CA B:GLY127 4.7 12.1 1.0 CA B:SER45 4.8 9.3 1.0 O3G B:ATP801 4.8 10.0 1.0 O B:SER45 4.8 23.0 1.0 CA B:GLU42 4.8 12.1 1.0 OG B:SER45 4.9 15.0 1.0 CA B:GLY132 5.0 13.6 1.0 O1B B:ATP801 5.0 18.1 1.0

S.Garcia-Alonso, P.Mesa, L.P.Ovejero, G.Aizpurua, C.G.Lechuga, E.Zarzuela, C.M.Santiveri, M.Sanclemente, J.Munoz, M.Musteanu, R.Campos-Olivas, J.Martinez-Torrecuadrada, M.Barbacid, G.Montoya. Structure of the RAF1-HSP90-CDC37 Complex Reveals the Basis of RAF1 Regulation. Mol.Cell V. 82 3438 2022.
ISSN: ISSN 1097-2765
PubMed: 36055235
DOI: 10.1016/J.MOLCEL.2022.08.012