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Atomistry » Magnesium » PDB 8a0m-8a6v » 8a6f | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 8a0m-8a6v » 8a6f » |
Magnesium in PDB 8a6f: Small Molecule Stabilizer (Compound 8) For C-Raf and 14-3-3Enzymatic activity of Small Molecule Stabilizer (Compound 8) For C-Raf and 14-3-3
All present enzymatic activity of Small Molecule Stabilizer (Compound 8) For C-Raf and 14-3-3:
2.7.11.1; Protein crystallography data
The structure of Small Molecule Stabilizer (Compound 8) For C-Raf and 14-3-3, PDB code: 8a6f
was solved by
D.N.Kenanova,
E.J.Visser,
J.Virta,
E.Sijbesma,
F.Centorrino,
M.Zhong,
H.Vickery,
J.Neitz,
L.Brunsveld,
C.Ottmann,
M.R.Arkin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8a6f:
The structure of Small Molecule Stabilizer (Compound 8) For C-Raf and 14-3-3 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Small Molecule Stabilizer (Compound 8) For C-Raf and 14-3-3
(pdb code 8a6f). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Small Molecule Stabilizer (Compound 8) For C-Raf and 14-3-3, PDB code: 8a6f: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 8a6fGo back to Magnesium Binding Sites List in 8a6f
Magnesium binding site 1 out
of 2 in the Small Molecule Stabilizer (Compound 8) For C-Raf and 14-3-3
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 8a6fGo back to Magnesium Binding Sites List in 8a6f
Magnesium binding site 2 out
of 2 in the Small Molecule Stabilizer (Compound 8) For C-Raf and 14-3-3
Mono view Stereo pair view
Reference:
D.N.Kenanova,
E.J.Visser,
J.M.Virta,
E.Sijbesma,
F.Centorrino,
H.R.Vickery,
M.Zhong,
R.J.Neitz,
L.Brunsveld,
C.Ottmann,
M.R.Arkin.
A Systematic Approach to the Discovery of Protein–Protein Interaction Stabilizers Acs Cent.Sci. 2023.
Page generated: Thu Oct 3 17:19:21 2024
ISSN: ESSN 2374-7951 DOI: 10.1021/ACSCENTSCI.2C01449 |
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