Magnesium in PDB 8act: Structure of the Human Beta-Cardiac Myosin Folded-Back Off State

The binding sites of Magnesium atom in the Structure of the Human Beta-Cardiac Myosin Folded-Back Off State (pdb code 8act). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of the Human Beta-Cardiac Myosin Folded-Back Off State, PDB code: 8act:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of the Human Beta-Cardiac Myosin Folded-Back Off State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the Human Beta-Cardiac Myosin Folded-Back Off State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1003 b:126.0 occ:1.00 O2B A:ADP1001 2.0 118.8 1.0 OG A:SER242 2.0 128.1 1.0 O4 A:PO41002 2.2 131.2 1.0 O1B A:ADP1001 2.2 118.8 1.0 PB A:ADP1001 2.4 118.8 1.0 O2 A:PO41002 3.0 131.2 1.0 CB A:SER242 3.0 128.1 1.0 P A:PO41002 3.1 131.2 1.0 O3B A:ADP1001 3.2 118.8 1.0 N A:SER242 3.4 128.1 1.0 OG1 A:THR185 3.5 114.1 1.0 O3A A:ADP1001 3.8 118.8 1.0 CA A:SER242 3.8 128.1 1.0 O1 A:PO41002 3.9 131.2 1.0 CE A:LYS184 4.3 108.5 1.0 O1A A:ADP1001 4.3 118.8 1.0 O3 A:PO41002 4.3 131.2 1.0 C A:SER241 4.4 129.1 1.0 PA A:ADP1001 4.6 118.8 1.0 ND2 A:ASN238 4.6 123.8 1.0 O A:SER242 4.6 128.1 1.0 CA A:SER241 4.7 129.1 1.0 C A:SER242 4.8 128.1 1.0 NZ A:LYS184 4.8 108.5 1.0 N A:THR185 4.8 114.1 1.0 CB A:LYS184 4.8 108.5 1.0 N A:GLY181 4.8 122.4 1.0 CB A:THR185 4.8 114.1 1.0 O A:ASN240 4.9 119.8 1.0 OD1 A:ASP461 4.9 134.9 1.0 O2A A:ADP1001 4.9 118.8 1.0 O A:ILE462 5.0 123.7 1.0

Magnesium binding site 2 out of 2 in the Structure of the Human Beta-Cardiac Myosin Folded-Back Off State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the Human Beta-Cardiac Myosin Folded-Back Off State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1003 b:158.9 occ:1.00 O2B B:ADP1001 1.8 169.8 1.0 O3 B:PO41002 2.1 183.2 1.0 OG1 B:THR185 2.1 157.8 1.0 O3B B:ADP1001 2.3 169.8 1.0 PB B:ADP1001 2.4 169.8 1.0 OG B:SER242 3.0 176.0 1.0 O1B B:ADP1001 3.3 169.8 1.0 P B:PO41002 3.3 183.2 1.0 CB B:THR185 3.4 157.8 1.0 CB B:SER242 3.7 176.0 1.0 O1 B:PO41002 3.7 183.2 1.0 O3A B:ADP1001 3.8 169.8 1.0 N B:SER242 3.8 176.0 1.0 O2 B:PO41002 3.9 183.2 1.0 O B:ASN240 3.9 179.8 1.0 N B:THR185 4.0 157.8 1.0 NZ B:LYS184 4.0 155.0 1.0 CA B:THR185 4.3 157.8 1.0 CG2 B:THR185 4.3 157.8 1.0 O1A B:ADP1001 4.4 169.8 1.0 CA B:SER242 4.4 176.0 1.0 OD2 B:ASP461 4.5 136.8 1.0 PA B:ADP1001 4.5 169.8 1.0 O4 B:PO41002 4.5 183.2 1.0 O2A B:ADP1001 4.6 169.8 1.0 OD1 B:ASP461 4.6 136.8 1.0 CE B:LYS184 4.7 155.0 1.0 C B:SER241 4.8 179.1 1.0 CA B:SER241 4.9 179.1 1.0 ND2 B:ASN232 5.0 185.5 1.0 CG B:ASP461 5.0 136.8 1.0

A.Grinzato, D.Auguin, C.Kikuti, N.Nandwani, D.Moussaoui, D.Pathak, E.Kandiah, K.M.Ruppel, J.A.Spudich, A.Houdusse, J.Robert-Paganin. Cryo-Em Structure of the Folded-Back State of Human Beta-Cardiac Myosin. Nat Commun V. 14 3166 2023.
ISSN: ESSN 2041-1723
PubMed: 37258552
DOI: 10.1038/S41467-023-38698-W