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Atomistry » Magnesium » PDB 8aq5-8avq » 8aq5 » |
Magnesium in PDB 8aq5: Kras G12C in Complex with Gdp and Compound 16Protein crystallography data
The structure of Kras G12C in Complex with Gdp and Compound 16, PDB code: 8aq5
was solved by
N.Ostermann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8aq5:
The structure of Kras G12C in Complex with Gdp and Compound 16 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Kras G12C in Complex with Gdp and Compound 16
(pdb code 8aq5). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Kras G12C in Complex with Gdp and Compound 16, PDB code: 8aq5: Magnesium binding site 1 out of 1 in 8aq5Go back to Magnesium Binding Sites List in 8aq5
Magnesium binding site 1 out
of 1 in the Kras G12C in Complex with Gdp and Compound 16
Mono view Stereo pair view
Reference:
E.Lorthiois,
M.Gerspacher,
K.S.Beyer,
A.Vaupel,
C.Leblanc,
R.Stringer,
A.Weiss,
R.Wilcken,
D.A.Guthy,
A.Lingel,
C.Bomio-Confaglia,
R.Machauer,
P.Rigollier,
J.Ottl,
D.Arz,
P.Bernet,
G.Desjonqueres,
S.Dussauge,
M.Kazic-Legueux,
M.A.Lozac'h,
C.Mura,
M.Sorge,
M.Todorov,
N.Warin,
F.Zink,
H.Voshol,
F.J.Zecri,
R.C.Sedrani,
N.Ostermann,
S.M.Brachmann,
S.Cotesta.
JDQ443, A Structurally Novel, Pyrazole-Based, Covalent Inhibitor of Kras G12C For the Treatment of Solid Tumors. J.Med.Chem. V. 65 16173 2022.
Page generated: Thu Oct 3 18:41:18 2024
ISSN: ISSN 0022-2623 PubMed: 36399068 DOI: 10.1021/ACS.JMEDCHEM.2C01438 |
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