Magnesium in PDB 8avy: The ABCB1 L335C Mutant (MABCB1) in the Apo State

All present enzymatic activity of The ABCB1 L335C Mutant (MABCB1) in the Apo State:
7.6.2.1; 7.6.2.2;

The binding sites of Magnesium atom in the The ABCB1 L335C Mutant (MABCB1) in the Apo State (pdb code 8avy). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the The ABCB1 L335C Mutant (MABCB1) in the Apo State, PDB code: 8avy:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the The ABCB1 L335C Mutant (MABCB1) in the Apo State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of The ABCB1 L335C Mutant (MABCB1) in the Apo State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2002 b:5.3 occ:1.00 O A:HOH2102 2.1 3.6 1.0 OG A:SER430 2.1 4.0 1.0 O A:HOH2103 2.1 6.0 1.0 O1G A:ATP2001 2.1 3.6 1.0 OE1 A:GLN471 2.1 23.6 1.0 CD A:GLN471 2.9 23.6 1.0 CB A:SER430 3.3 4.0 1.0 O2B A:ATP2001 3.4 3.6 1.0 PG A:ATP2001 3.6 3.6 1.0 NE2 A:GLN471 3.6 23.6 1.0 OD1 A:ASP551 3.6 21.5 1.0 OD2 A:ASP551 3.6 21.5 1.0 CG A:GLN471 3.9 23.6 1.0 CG A:ASP551 4.0 21.5 1.0 CB A:GLN471 4.0 23.6 1.0 O3A A:ATP2001 4.2 3.6 1.0 O3B A:ATP2001 4.2 3.6 1.0 PB A:ATP2001 4.2 3.6 1.0 O2G A:ATP2001 4.3 3.6 1.0 O3G A:ATP2001 4.4 3.6 1.0 CA A:SER430 4.5 4.0 1.0 N A:SER430 4.7 4.0 1.0 N A:GLY1174 4.7 8.5 1.0 CG A:GLU552 4.7 24.6 1.0 O1A A:ATP2001 4.9 3.6 1.0

Magnesium binding site 2 out of 2 in the The ABCB1 L335C Mutant (MABCB1) in the Apo State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of The ABCB1 L335C Mutant (MABCB1) in the Apo State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2004 b:4.7 occ:1.00 O3G A:ATP2003 2.0 3.6 1.0 O A:HOH2101 2.0 3.6 1.0 OE1 A:GLN1114 2.1 17.8 1.0 OG A:SER1073 2.1 3.6 1.0 O A:HOH2104 2.2 7.9 1.0 O1B A:ATP2003 2.2 3.6 1.0 CD A:GLN1114 3.1 17.8 1.0 PG A:ATP2003 3.1 3.6 1.0 CB A:SER1073 3.2 3.6 1.0 PB A:ATP2003 3.2 3.6 1.0 O3B A:ATP2003 3.3 3.6 1.0 O2G A:ATP2003 3.5 3.6 1.0 NE2 A:GLN1114 3.6 17.8 1.0 O3A A:ATP2003 3.9 3.6 1.0 OD1 A:ASP1196 4.1 22.8 1.0 O1A A:ATP2003 4.1 3.6 1.0 N A:SER1073 4.2 3.6 1.0 OD2 A:ASP1196 4.2 22.8 1.0 CA A:SER1073 4.2 3.6 1.0 CG A:GLN1114 4.3 17.8 1.0 O1G A:ATP2003 4.4 3.6 1.0 N A:GLY529 4.5 3.6 1.0 O2B A:ATP2003 4.5 3.6 1.0 CG A:ASP1196 4.6 22.8 1.0 PA A:ATP2003 4.6 3.6 1.0 CB A:GLN1114 4.6 17.8 1.0 CB A:SER528 4.9 3.6 1.0

K.Parey, D.Januliene, T.Gewering, A.Moeller, D.Waghray, I.Urbatsch, Q.Zhang. The ABCB1 L335C Mutant (MABCB1) in the Apo State To Be Published.