Magnesium in PDB 8css: Human Mitochondrial Small Subunit Assembly Intermediate (State D)
Enzymatic activity of Human Mitochondrial Small Subunit Assembly Intermediate (State D)
All present enzymatic activity of Human Mitochondrial Small Subunit Assembly Intermediate (State D):
2.3.1.39;
Other elements in 8css:
The structure of Human Mitochondrial Small Subunit Assembly Intermediate (State D) also contains other interesting chemical elements:
Magnesium Binding Sites:
Magnesium binding site 1 out
of 32 in 8css
Go back to
Magnesium Binding Sites List in 8css
Magnesium binding site 1 out
of 32 in the Human Mitochondrial Small Subunit Assembly Intermediate (State D)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Human Mitochondrial Small Subunit Assembly Intermediate (State D) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1708
b:33.3
occ:1.00
|
O1A
|
A:NAD1738
|
2.0
|
29.7
|
1.0
|
O
|
A:HOH1843
|
2.0
|
28.8
|
1.0
|
O
|
A:HOH1881
|
2.0
|
38.1
|
1.0
|
O
|
A:HOH1854
|
2.4
|
37.5
|
1.0
|
O
|
A:HOH1806
|
2.5
|
30.0
|
1.0
|
O
|
A:HOH1877
|
2.5
|
35.1
|
1.0
|
PA
|
A:NAD1738
|
3.4
|
29.7
|
1.0
|
O2'
|
A:A757
|
3.8
|
26.2
|
1.0
|
O2N
|
A:NAD1738
|
4.0
|
29.7
|
1.0
|
O2A
|
A:NAD1738
|
4.1
|
29.7
|
1.0
|
N4
|
A:C1048
|
4.1
|
32.3
|
1.0
|
O5B
|
A:NAD1738
|
4.1
|
29.7
|
1.0
|
O1N
|
A:NAD1738
|
4.3
|
29.7
|
1.0
|
N1
|
A:A783
|
4.3
|
27.5
|
1.0
|
N6
|
A:A783
|
4.3
|
27.5
|
1.0
|
O3
|
A:NAD1738
|
4.4
|
29.7
|
1.0
|
O
|
A:HOH1867
|
4.4
|
32.1
|
1.0
|
O
|
A:HOH1817
|
4.4
|
30.4
|
1.0
|
C5B
|
A:NAD1738
|
4.4
|
29.7
|
1.0
|
PN
|
A:NAD1738
|
4.5
|
29.7
|
1.0
|
C6
|
A:A783
|
4.9
|
27.5
|
1.0
|
C2'
|
A:A757
|
4.9
|
26.2
|
1.0
|
|
Magnesium binding site 2 out
of 32 in 8css
Go back to
Magnesium Binding Sites List in 8css
Magnesium binding site 2 out
of 32 in the Human Mitochondrial Small Subunit Assembly Intermediate (State D)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Human Mitochondrial Small Subunit Assembly Intermediate (State D) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1709
b:33.8
occ:1.00
|
O
|
A:HOH1892
|
2.3
|
30.3
|
1.0
|
O
|
A:HOH1803
|
2.8
|
25.9
|
1.0
|
OP1
|
A:A1046
|
3.2
|
27.8
|
1.0
|
O4'
|
A:G1134
|
3.8
|
33.7
|
1.0
|
O
|
A:HOH1860
|
3.8
|
20.8
|
1.0
|
O5'
|
A:A1046
|
4.0
|
27.8
|
1.0
|
C5'
|
A:A1046
|
4.1
|
27.8
|
1.0
|
P
|
A:A1046
|
4.1
|
27.8
|
1.0
|
C4'
|
A:G1134
|
4.2
|
33.7
|
1.0
|
O
|
A:HOH1841
|
4.2
|
21.1
|
1.0
|
C1'
|
A:G1134
|
4.2
|
33.7
|
1.0
|
O2'
|
A:G1134
|
4.3
|
33.7
|
1.0
|
O
|
A:HOH1887
|
4.3
|
34.0
|
1.0
|
OP2
|
A:A1047
|
4.3
|
31.7
|
1.0
|
N7
|
A:A942
|
4.4
|
36.0
|
1.0
|
MG
|
A:MG1715
|
4.6
|
26.4
|
1.0
|
N2
|
A:G941
|
4.6
|
33.7
|
1.0
|
O2'
|
A:C1133
|
4.7
|
33.7
|
1.0
|
OP2
|
A:A1046
|
4.8
|
27.8
|
1.0
|
C2'
|
A:G1134
|
4.8
|
33.7
|
1.0
|
C3'
|
A:A1046
|
4.9
|
27.8
|
1.0
|
O2
|
A:C1133
|
5.0
|
33.7
|
1.0
|
|
Magnesium binding site 3 out
of 32 in 8css
Go back to
Magnesium Binding Sites List in 8css
Magnesium binding site 3 out
of 32 in the Human Mitochondrial Small Subunit Assembly Intermediate (State D)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Human Mitochondrial Small Subunit Assembly Intermediate (State D) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1710
b:33.2
occ:1.00
|
O
|
A:HOH1882
|
2.0
|
32.2
|
1.0
|
O
|
A:HOH1886
|
2.0
|
35.7
|
1.0
|
OP1
|
A:G1092
|
2.0
|
31.0
|
1.0
|
O
|
A:HOH1893
|
2.0
|
33.5
|
1.0
|
O
|
A:HOH1873
|
2.1
|
35.4
|
1.0
|
O
|
A:HOH1833
|
2.3
|
30.8
|
1.0
|
P
|
A:G1092
|
3.5
|
31.0
|
1.0
|
O
|
A:HOH1855
|
3.8
|
30.3
|
1.0
|
O3'
|
A:U1091
|
4.1
|
32.7
|
1.0
|
O
|
A:HOH1872
|
4.1
|
32.7
|
1.0
|
OP2
|
A:G1092
|
4.4
|
31.0
|
1.0
|
OP2
|
A:C1093
|
4.4
|
39.2
|
1.0
|
N4
|
A:C1058
|
4.4
|
38.7
|
1.0
|
O5'
|
A:G1092
|
4.4
|
31.0
|
1.0
|
C5'
|
A:G1092
|
4.6
|
31.0
|
1.0
|
O6
|
A:G1057
|
4.7
|
31.1
|
1.0
|
N7
|
A:G1057
|
4.7
|
31.1
|
1.0
|
|
Magnesium binding site 4 out
of 32 in 8css
Go back to
Magnesium Binding Sites List in 8css
Magnesium binding site 4 out
of 32 in the Human Mitochondrial Small Subunit Assembly Intermediate (State D)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of Human Mitochondrial Small Subunit Assembly Intermediate (State D) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1711
b:28.1
occ:1.00
|
OP2
|
A:G791
|
2.0
|
31.7
|
1.0
|
O
|
A:HOH1838
|
2.0
|
31.5
|
1.0
|
O
|
A:HOH1820
|
2.0
|
26.3
|
1.0
|
OP2
|
A:A718
|
2.0
|
25.9
|
1.0
|
O
|
A:HOH1861
|
2.1
|
28.0
|
1.0
|
OP2
|
A:G719
|
2.2
|
24.6
|
1.0
|
P
|
A:G791
|
3.4
|
31.7
|
1.0
|
P
|
A:A718
|
3.5
|
25.9
|
1.0
|
P
|
A:G719
|
3.6
|
24.6
|
1.0
|
O5'
|
A:G791
|
3.8
|
31.7
|
1.0
|
OP1
|
A:A718
|
4.3
|
25.9
|
1.0
|
O3'
|
A:G717
|
4.3
|
33.7
|
1.0
|
O5'
|
A:A790
|
4.3
|
25.2
|
1.0
|
OP1
|
A:G791
|
4.4
|
31.7
|
1.0
|
OP1
|
A:G719
|
4.4
|
24.6
|
1.0
|
O5'
|
A:A718
|
4.4
|
25.9
|
1.0
|
K
|
A:K1702
|
4.4
|
23.7
|
1.0
|
O3'
|
A:A718
|
4.4
|
25.9
|
1.0
|
O3'
|
A:A790
|
4.4
|
25.2
|
1.0
|
C3'
|
A:A790
|
4.4
|
25.2
|
1.0
|
C5'
|
A:A718
|
4.5
|
25.9
|
1.0
|
OP2
|
A:A790
|
4.5
|
25.2
|
1.0
|
C3'
|
A:A718
|
4.6
|
25.9
|
1.0
|
O5'
|
A:G719
|
4.6
|
24.6
|
1.0
|
O4
|
A:U720
|
4.7
|
23.8
|
1.0
|
P
|
A:A790
|
4.9
|
25.2
|
1.0
|
N7
|
A:G719
|
4.9
|
24.6
|
1.0
|
|
Magnesium binding site 5 out
of 32 in 8css
Go back to
Magnesium Binding Sites List in 8css
Magnesium binding site 5 out
of 32 in the Human Mitochondrial Small Subunit Assembly Intermediate (State D)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 5 of Human Mitochondrial Small Subunit Assembly Intermediate (State D) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1712
b:25.4
occ:1.00
|
OP2
|
A:A940
|
2.0
|
33.7
|
1.0
|
O
|
A:HOH1870
|
2.0
|
32.3
|
1.0
|
O
|
A:HOH1819
|
2.0
|
32.0
|
1.0
|
O
|
A:HOH1811
|
2.1
|
29.0
|
1.0
|
OP2
|
A:A939
|
2.3
|
29.5
|
1.0
|
OP2
|
A:A938
|
2.9
|
34.8
|
1.0
|
P
|
A:A940
|
3.3
|
33.7
|
1.0
|
P
|
A:A939
|
3.5
|
29.5
|
1.0
|
P
|
A:A938
|
3.7
|
34.8
|
1.0
|
OP1
|
A:A939
|
3.7
|
29.5
|
1.0
|
OP1
|
A:U937
|
3.8
|
28.0
|
1.0
|
O5'
|
A:A938
|
3.8
|
34.8
|
1.0
|
OP1
|
A:A940
|
3.9
|
33.7
|
1.0
|
OP1
|
A:A938
|
4.0
|
34.8
|
1.0
|
C5'
|
A:A938
|
4.1
|
34.8
|
1.0
|
O3'
|
A:A939
|
4.3
|
29.5
|
1.0
|
C3'
|
A:A939
|
4.4
|
29.5
|
1.0
|
O5'
|
A:A940
|
4.4
|
33.7
|
1.0
|
O5'
|
A:A939
|
4.5
|
29.5
|
1.0
|
O3'
|
A:A938
|
4.6
|
34.8
|
1.0
|
P
|
A:U937
|
4.7
|
28.0
|
1.0
|
OP2
|
A:U937
|
4.8
|
28.0
|
1.0
|
C5'
|
A:A939
|
4.9
|
29.5
|
1.0
|
C3'
|
A:A938
|
4.9
|
34.8
|
1.0
|
|
Magnesium binding site 6 out
of 32 in 8css
Go back to
Magnesium Binding Sites List in 8css
Magnesium binding site 6 out
of 32 in the Human Mitochondrial Small Subunit Assembly Intermediate (State D)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 6 of Human Mitochondrial Small Subunit Assembly Intermediate (State D) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1713
b:34.1
occ:1.00
|
O
|
A:HOH1874
|
2.0
|
30.0
|
1.0
|
O
|
A:HOH1878
|
2.0
|
30.6
|
1.0
|
O
|
A:HOH1866
|
2.0
|
31.1
|
1.0
|
O
|
A:HOH1898
|
2.0
|
35.2
|
1.0
|
O
|
A:HOH1827
|
2.1
|
29.5
|
1.0
|
O
|
A:HOH1831
|
2.3
|
33.8
|
1.0
|
O
|
A:HOH1844
|
3.8
|
30.7
|
1.0
|
OP2
|
A:G1028
|
4.0
|
33.7
|
1.0
|
OP1
|
A:A1027
|
4.0
|
33.7
|
1.0
|
OP1
|
A:G1028
|
4.2
|
33.7
|
1.0
|
OP2
|
A:A1104
|
4.3
|
33.7
|
1.0
|
P
|
A:G1028
|
4.4
|
33.7
|
1.0
|
N1
|
A:A1102
|
4.5
|
33.7
|
1.0
|
O3'
|
A:A1027
|
4.6
|
33.7
|
1.0
|
O3'
|
A:C1591
|
4.6
|
33.7
|
1.0
|
C5'
|
A:A1027
|
4.6
|
33.7
|
1.0
|
O2'
|
A:C1591
|
4.8
|
33.7
|
1.0
|
O2'
|
A:A1104
|
4.9
|
33.7
|
1.0
|
OP1
|
A:U1592
|
4.9
|
33.7
|
1.0
|
|
Magnesium binding site 7 out
of 32 in 8css
Go back to
Magnesium Binding Sites List in 8css
Magnesium binding site 7 out
of 32 in the Human Mitochondrial Small Subunit Assembly Intermediate (State D)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 7 of Human Mitochondrial Small Subunit Assembly Intermediate (State D) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1714
b:30.7
occ:1.00
|
OP2
|
A:A1054
|
2.0
|
37.6
|
1.0
|
O
|
A:HOH1879
|
2.0
|
33.6
|
1.0
|
O
|
A:HOH1858
|
2.0
|
28.9
|
1.0
|
O
|
A:HOH1885
|
2.0
|
38.4
|
1.0
|
O
|
A:HOH1801
|
2.1
|
30.1
|
1.0
|
O
|
A:HOH1805
|
2.7
|
30.2
|
1.0
|
P
|
A:A1054
|
3.3
|
37.6
|
1.0
|
OP1
|
A:A1054
|
3.8
|
37.6
|
1.0
|
N4
|
A:C1099
|
4.0
|
34.2
|
1.0
|
N3
|
A:C1099
|
4.2
|
34.2
|
1.0
|
O3'
|
A:A1053
|
4.2
|
26.6
|
1.0
|
O2
|
A:C1100
|
4.3
|
30.5
|
1.0
|
C3'
|
A:A1053
|
4.3
|
26.6
|
1.0
|
O5'
|
A:A1054
|
4.4
|
37.6
|
1.0
|
C4
|
A:C1099
|
4.6
|
34.2
|
1.0
|
O
|
A:HOH1859
|
4.7
|
24.7
|
1.0
|
O4
|
A:U1055
|
4.7
|
33.7
|
1.0
|
N6
|
A:A1056
|
4.8
|
36.2
|
1.0
|
N3
|
A:C1100
|
4.8
|
30.5
|
1.0
|
C2
|
A:C1100
|
4.8
|
30.5
|
1.0
|
O4
|
A:U1101
|
4.9
|
31.0
|
1.0
|
|
Magnesium binding site 8 out
of 32 in 8css
Go back to
Magnesium Binding Sites List in 8css
Magnesium binding site 8 out
of 32 in the Human Mitochondrial Small Subunit Assembly Intermediate (State D)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 8 of Human Mitochondrial Small Subunit Assembly Intermediate (State D) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1715
b:26.4
occ:1.00
|
OP1
|
A:G1045
|
2.1
|
23.9
|
1.0
|
O
|
A:HOH1841
|
2.1
|
21.1
|
1.0
|
O
|
A:HOH1860
|
2.1
|
20.8
|
1.0
|
O
|
A:HOH1832
|
2.1
|
24.4
|
1.0
|
O
|
A:HOH1850
|
2.3
|
24.2
|
1.0
|
O
|
A:HOH1887
|
2.4
|
34.0
|
1.0
|
P
|
A:G1045
|
3.5
|
23.9
|
1.0
|
O
|
A:HOH1892
|
4.0
|
30.3
|
1.0
|
OP1
|
A:A1046
|
4.1
|
27.8
|
1.0
|
O5'
|
A:G1045
|
4.1
|
23.9
|
1.0
|
C5'
|
A:G1045
|
4.2
|
23.9
|
1.0
|
O3'
|
A:U1044
|
4.3
|
32.1
|
1.0
|
O2'
|
A:A1109
|
4.4
|
33.7
|
1.0
|
O2
|
A:C1133
|
4.4
|
33.7
|
1.0
|
O4'
|
A:A1110
|
4.5
|
27.3
|
1.0
|
OP2
|
A:G1045
|
4.5
|
23.9
|
1.0
|
N2
|
A:G941
|
4.6
|
33.7
|
1.0
|
MG
|
A:MG1709
|
4.6
|
33.8
|
1.0
|
N3
|
A:A1109
|
4.6
|
33.7
|
1.0
|
|
Magnesium binding site 9 out
of 32 in 8css
Go back to
Magnesium Binding Sites List in 8css
Magnesium binding site 9 out
of 32 in the Human Mitochondrial Small Subunit Assembly Intermediate (State D)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 9 of Human Mitochondrial Small Subunit Assembly Intermediate (State D) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1716
b:23.0
occ:1.00
|
OP2
|
A:U947
|
2.0
|
26.5
|
1.0
|
O
|
A:HOH1821
|
2.0
|
29.4
|
1.0
|
O
|
A:HOH1823
|
2.2
|
23.4
|
1.0
|
O
|
A:HOH1828
|
2.3
|
26.0
|
1.0
|
O
|
A:HOH1888
|
2.4
|
24.4
|
1.0
|
N7
|
A:G1045
|
2.6
|
23.9
|
1.0
|
P
|
A:U947
|
3.3
|
26.5
|
1.0
|
C8
|
A:G1045
|
3.5
|
23.9
|
1.0
|
C5
|
A:G1045
|
3.6
|
23.9
|
1.0
|
O6
|
A:G1045
|
3.7
|
23.9
|
1.0
|
OP1
|
A:U947
|
3.8
|
26.5
|
1.0
|
C6
|
A:G1045
|
4.0
|
23.9
|
1.0
|
OP2
|
A:U1044
|
4.2
|
32.1
|
1.0
|
OP2
|
A:U946
|
4.3
|
23.4
|
1.0
|
OP1
|
A:U946
|
4.3
|
23.4
|
1.0
|
O3'
|
A:U946
|
4.3
|
23.4
|
1.0
|
OP2
|
A:G1045
|
4.3
|
23.9
|
1.0
|
O5'
|
A:U946
|
4.3
|
23.4
|
1.0
|
O5'
|
A:U947
|
4.3
|
26.5
|
1.0
|
C5
|
A:U947
|
4.4
|
26.5
|
1.0
|
P
|
A:U946
|
4.5
|
23.4
|
1.0
|
C3'
|
A:U946
|
4.5
|
23.4
|
1.0
|
N9
|
A:G1045
|
4.7
|
23.9
|
1.0
|
C4
|
A:G1045
|
4.8
|
23.9
|
1.0
|
O
|
A:HOH1808
|
4.8
|
21.9
|
1.0
|
C6
|
A:U947
|
4.9
|
26.5
|
1.0
|
C5'
|
A:U946
|
5.0
|
23.4
|
1.0
|
|
Magnesium binding site 10 out
of 32 in 8css
Go back to
Magnesium Binding Sites List in 8css
Magnesium binding site 10 out
of 32 in the Human Mitochondrial Small Subunit Assembly Intermediate (State D)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 10 of Human Mitochondrial Small Subunit Assembly Intermediate (State D) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1717
b:39.2
occ:1.00
|
O
|
A:HOH1895
|
2.0
|
32.3
|
1.0
|
O
|
A:HOH1883
|
2.2
|
30.4
|
1.0
|
OP1
|
A:U655
|
2.9
|
30.7
|
1.0
|
OP2
|
A:U656
|
3.1
|
30.9
|
1.0
|
C5
|
A:U656
|
3.4
|
30.9
|
1.0
|
O5'
|
A:U655
|
3.4
|
30.7
|
1.0
|
P
|
A:U655
|
3.7
|
30.7
|
1.0
|
C6
|
A:U656
|
4.0
|
30.9
|
1.0
|
C4
|
A:U656
|
4.2
|
30.9
|
1.0
|
P
|
A:U656
|
4.4
|
30.9
|
1.0
|
O4
|
A:U656
|
4.4
|
30.9
|
1.0
|
OP2
|
A:U655
|
4.4
|
30.7
|
1.0
|
O5'
|
A:U656
|
4.5
|
30.9
|
1.0
|
C5'
|
A:U655
|
4.7
|
30.7
|
1.0
|
C3'
|
A:U655
|
4.7
|
30.7
|
1.0
|
OP2
|
A:G658
|
4.9
|
33.7
|
1.0
|
OP1
|
A:G658
|
5.0
|
33.7
|
1.0
|
|
Reference:
N.J.Harper,
C.Burnside,
S.Klinge.
Principles of Mitoribosomal Small Subunit Assembly in Eukaryotes. Nature 2022.
ISSN: ESSN 1476-4687
PubMed: 36482135
DOI: 10.1038/S41586-022-05621-0
Page generated: Thu Oct 3 23:16:56 2024
|