Magnesium in PDB 8dsw: Crystal Structure of Egfr Kinase Domain, EXON20 Insertion Fqea Mutant

All present enzymatic activity of Crystal Structure of Egfr Kinase Domain, EXON20 Insertion Fqea Mutant:
2.7.10.1;

The structure of Crystal Structure of Egfr Kinase Domain, EXON20 Insertion Fqea Mutant, PDB code: 8dsw was solved by E.Park, M.J.Eck, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.98 / 2.39
Space group	I 2 3
Cell size a, b, c (Å), α, β, γ (°)	148.555, 148.555, 148.555, 90, 90, 90
R / Rfree (%)	19.2 / 24.6

The binding sites of Magnesium atom in the Crystal Structure of Egfr Kinase Domain, EXON20 Insertion Fqea Mutant (pdb code 8dsw). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Egfr Kinase Domain, EXON20 Insertion Fqea Mutant, PDB code: 8dsw:

Magnesium binding site 1 out of 1 in the Crystal Structure of Egfr Kinase Domain, EXON20 Insertion Fqea Mutant


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Egfr Kinase Domain, EXON20 Insertion Fqea Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1103 b:45.7 occ:1.00 OE2 A:GLU762 1.8 84.0 1.0 OD1 A:ASP859 2.0 67.1 1.0 CD A:GLU762 3.0 81.1 1.0 CG A:ASP859 3.1 66.2 1.0 OE2 A:GLU766 3.1 86.2 1.0 OD2 A:ASP859 3.4 72.2 1.0 O2B A:ANP1104 3.6 106.2 1.0 OE1 A:GLU762 3.6 77.9 1.0 CA A:GLY861 4.0 53.7 1.0 N A:GLY861 4.0 55.0 1.0 CG A:GLU762 4.1 70.0 1.0 CD A:GLU766 4.2 85.0 1.0 CB A:ASP859 4.4 54.5 1.0 OE1 A:GLU766 4.5 95.2 1.0 CA A:ASP859 4.6 58.7 1.0 C A:ASP859 4.8 53.5 1.0

E.Park, M.J.Eck. Structural Basis For Oncogenic Activation of the Epidermal Growth Factor Receptor By the Insfqea Exon 20 Insertion To Be Published.