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Magnesium in PDB 8ezg: Monobody 12D1 Bound to Kras(G12D)Enzymatic activity of Monobody 12D1 Bound to Kras(G12D)
All present enzymatic activity of Monobody 12D1 Bound to Kras(G12D):
3.6.5.2; Protein crystallography data
The structure of Monobody 12D1 Bound to Kras(G12D), PDB code: 8ezg
was solved by
T.Hattori,
E.Glasser,
P.Akkapeddi,
G.Ketavarapu,
K.W.Teng,
A.Koide,
S.Koide,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8ezg:
The structure of Monobody 12D1 Bound to Kras(G12D) also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Monobody 12D1 Bound to Kras(G12D)
(pdb code 8ezg). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Monobody 12D1 Bound to Kras(G12D), PDB code: 8ezg: Magnesium binding site 1 out of 1 in 8ezgGo back to Magnesium Binding Sites List in 8ezg
Magnesium binding site 1 out
of 1 in the Monobody 12D1 Bound to Kras(G12D)
Mono view Stereo pair view
Reference:
P.Akkapeddi,
T.Hattori,
I.Khan,
E.Glasser,
A.Koide,
G.Ketavarapu,
M.Whaby,
M.Zuberi,
K.W.Teng,
J.Lefler,
L.Maso,
I.Bang,
M.C.Ostrowski,
J.P.O'bryan,
S.Koide.
Exploring Switch II Pocket Conformation of Kras(G12D) with Mutant-Selective Monobody Inhibitors. Proc.Natl.Acad.Sci.Usa V. 120 85120 2023.
Page generated: Fri Oct 4 01:24:55 2024
ISSN: ESSN 1091-6490 PubMed: 37399416 DOI: 10.1073/PNAS.2302485120 |
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