Magnesium in PDB 8fvs: Bromodomain of Cbp Liganded with CCS1477INT

All present enzymatic activity of Bromodomain of Cbp Liganded with CCS1477INT:
2.3.1.48;

The structure of Bromodomain of Cbp Liganded with CCS1477INT, PDB code: 8fvs was solved by E.Schonbrunn, M.Bikowitz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.79 / 1.75
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	35.07, 79.19, 46.13, 90, 93.85, 90
R / Rfree (%)	15.2 / 18.1

The binding sites of Magnesium atom in the Bromodomain of Cbp Liganded with CCS1477INT (pdb code 8fvs). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Bromodomain of Cbp Liganded with CCS1477INT, PDB code: 8fvs:

Magnesium binding site 1 out of 1 in the Bromodomain of Cbp Liganded with CCS1477INT


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Bromodomain of Cbp Liganded with CCS1477INT within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1202 b:33.6 occ:1.00 O B:HOH1426 2.1 30.6 1.0 O B:HOH1433 2.1 27.6 1.0 O B:HOH1305 3.7 26.7 1.0 O B:HOH1374 4.2 24.4 1.0 OE1 B:GLU1186 4.4 31.7 1.0 O B:HOH1335 4.5 17.4 1.0

E.Schonbrunn, M.Bikowitz. Group 3 Medulloblastoma Transcriptional Networks Are Sensitive to EP300/Cbp Bromodomain Inhibition To Be Published.