Magnesium in PDB 8g47: Kras G12C Complex with Gdp and Amg 510 Imaged on A Cryo-Em Imaging Scaffold

All present enzymatic activity of Kras G12C Complex with Gdp and Amg 510 Imaged on A Cryo-Em Imaging Scaffold:
3.6.5.2;

The structure of Kras G12C Complex with Gdp and Amg 510 Imaged on A Cryo-Em Imaging Scaffold also contains other interesting chemical elements:

Fluorine

(F)

2 atoms

The binding sites of Magnesium atom in the Kras G12C Complex with Gdp and Amg 510 Imaged on A Cryo-Em Imaging Scaffold (pdb code 8g47). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Kras G12C Complex with Gdp and Amg 510 Imaged on A Cryo-Em Imaging Scaffold, PDB code: 8g47:

Magnesium binding site 1 out of 1 in the Kras G12C Complex with Gdp and Amg 510 Imaged on A Cryo-Em Imaging Scaffold


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Kras G12C Complex with Gdp and Amg 510 Imaged on A Cryo-Em Imaging Scaffold within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg201 b:26.8 occ:1.00 O2B B:GDP202 2.1 34.1 1.0 OG B:SER17 2.1 43.5 1.0 CB B:SER17 3.4 36.6 1.0 CB B:ALA59 3.4 74.0 1.0 OD2 B:ASP57 3.4 73.2 1.0 PB B:GDP202 3.5 34.1 1.0 O B:PRO34 3.8 82.7 1.0 O B:ASP33 3.9 75.8 1.0 O B:ILE36 4.0 76.0 1.0 OD1 B:ASP57 4.0 70.6 1.0 CG B:ASP57 4.1 63.2 1.0 O1B B:GDP202 4.1 34.1 1.0 O3B B:GDP202 4.1 34.1 1.0 CD2 B:TYR32 4.3 61.1 1.0 N B:SER17 4.3 42.1 1.0 CA B:SER17 4.4 27.0 1.0 C B:PRO34 4.4 80.4 1.0 CE2 B:TYR32 4.5 59.2 1.0 O3A B:GDP202 4.6 34.1 1.0 O2A B:GDP202 4.7 34.1 1.0 CA B:ALA59 4.7 73.8 1.0 CA B:PRO34 4.8 74.9 1.0 O1A B:GDP202 4.8 34.1 1.0 N B:ILE36 4.8 68.4 1.0 PA B:GDP202 4.9 34.1 1.0 O2 B:MOV203 4.9 100.4 1.0 C B:ASP33 5.0 70.1 1.0

R.Castells-Graells, K.Meador, M.A.Arbing, M.R.Sawaya, M.Gee, D.Cascio, E.Gleave, J.E.Debreczeni, J.Breed, K.Leopold, A.Patel, D.Jahagirdar, D.Lyons, S.Subramaniam, C.Phillips, T.O.Yeates. Structures of the Kras Protein Cancer Target at 3 Angstrom Resolution By Cryo-Em Scaffolding To Be Published.