Magnesium in PDB 8i0i: Dmctps with Datp Dutp Dgtp and Don

All present enzymatic activity of Dmctps with Datp Dutp Dgtp and Don:
6.3.4.2;

The binding sites of Magnesium atom in the Dmctps with Datp Dutp Dgtp and Don (pdb code 8i0i). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Dmctps with Datp Dutp Dgtp and Don, PDB code: 8i0i:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Dmctps with Datp Dutp Dgtp and Don


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Dmctps with Datp Dutp Dgtp and Don within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg603 b:44.8 occ:1.00 O2A C:DUT602 2.1 44.0 1.0 O2G C:DUT602 2.8 44.0 1.0 PA C:DUT602 3.6 44.0 1.0 O2B C:DUT602 3.7 44.0 1.0 O1A C:DUT602 4.2 44.0 1.0 PG C:DUT602 4.3 44.0 1.0 O3A C:DUT602 4.5 44.0 1.0 O5' C:DUT602 4.5 44.0 1.0 PB C:DUT602 4.6 44.0 1.0 NZ A:LYS192 4.7 42.0 1.0 O3B C:DUT602 4.8 44.0 1.0 O3G C:DUT602 4.9 44.0 1.0 OE2 A:GLU190 4.9 54.0 1.0

Magnesium binding site 2 out of 4 in the Dmctps with Datp Dutp Dgtp and Don


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Dmctps with Datp Dutp Dgtp and Don within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg603 b:47.5 occ:1.00 O2A A:DUT602 2.1 44.1 1.0 O2G A:DUT602 2.8 44.1 1.0 PA A:DUT602 3.6 44.1 1.0 O2B A:DUT602 3.7 44.1 1.0 O1A A:DUT602 4.2 44.1 1.0 PG A:DUT602 4.2 44.1 1.0 O3A A:DUT602 4.5 44.1 1.0 O5' A:DUT602 4.5 44.1 1.0 PB A:DUT602 4.6 44.1 1.0 NZ C:LYS192 4.6 42.0 1.0 O3B A:DUT602 4.8 44.1 1.0 O3G A:DUT602 4.9 44.1 1.0 OE2 C:GLU190 4.9 54.9 1.0

Magnesium binding site 3 out of 4 in the Dmctps with Datp Dutp Dgtp and Don


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Dmctps with Datp Dutp Dgtp and Don within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg603 b:46.8 occ:1.00 O1A E:DUT602 2.1 44.1 1.0 O2G E:DUT602 2.8 44.1 1.0 PA E:DUT602 3.6 44.1 1.0 O1B E:DUT602 3.7 44.1 1.0 PG E:DUT602 4.2 44.1 1.0 O2A E:DUT602 4.2 44.1 1.0 O3A E:DUT602 4.5 44.1 1.0 PB E:DUT602 4.6 44.1 1.0 O5' E:DUT602 4.6 44.1 1.0 NZ D:LYS192 4.7 41.6 1.0 O3B E:DUT602 4.8 44.1 1.0 OE2 D:GLU190 4.8 53.9 1.0 O1G E:DUT602 4.8 44.1 1.0

Magnesium binding site 4 out of 4 in the Dmctps with Datp Dutp Dgtp and Don


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Dmctps with Datp Dutp Dgtp and Don within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg603 b:45.4 occ:1.00 O1A D:DUT602 2.1 44.1 1.0 O2G D:DUT602 2.8 44.1 1.0 PA D:DUT602 3.6 44.1 1.0 O1B D:DUT602 3.7 44.1 1.0 O2A D:DUT602 4.2 44.1 1.0 PG D:DUT602 4.2 44.1 1.0 O3A D:DUT602 4.5 44.1 1.0 PB D:DUT602 4.6 44.1 1.0 O5' D:DUT602 4.6 44.1 1.0 NZ E:LYS192 4.6 41.4 1.0 O1G D:DUT602 4.8 44.1 1.0 O3B D:DUT602 4.8 44.1 1.0 OE2 E:GLU190 4.9 54.2 1.0

C.J.Guo, Z.Zhang, J.Zhong, J.L.Liu. Structural Basis of Bifunctional Ctp/Dctp Synthase Biorxiv 2023.
ISSN: ISSN 2692-8205
DOI: 10.1101/2023.02.19.529158