Magnesium in PDB 8jwi: Cryo-Em Structure of the Outward-Facing Plasmodium Falciparum Multidrug Resistance Protein 1

The binding sites of Magnesium atom in the Cryo-Em Structure of the Outward-Facing Plasmodium Falciparum Multidrug Resistance Protein 1 (pdb code 8jwi). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Cryo-Em Structure of the Outward-Facing Plasmodium Falciparum Multidrug Resistance Protein 1, PDB code: 8jwi:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Cryo-Em Structure of the Outward-Facing Plasmodium Falciparum Multidrug Resistance Protein 1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of the Outward-Facing Plasmodium Falciparum Multidrug Resistance Protein 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1503 b:74.0 occ:1.00 O2G A:ATP1502 2.0 80.2 1.0 OE1 A:GLN1256 2.0 73.5 1.0 NE2 A:GLN1256 2.2 73.5 1.0 CD A:GLN1256 2.3 73.5 1.0 O2B A:ATP1502 3.1 80.2 1.0 OG A:SER1168 3.2 76.9 1.0 PG A:ATP1502 3.5 80.2 1.0 CG A:GLN1256 3.7 73.5 1.0 CB A:SER1168 3.9 76.9 1.0 O1G A:ATP1502 4.2 80.2 1.0 PB A:ATP1502 4.2 80.2 1.0 O3B A:ATP1502 4.2 80.2 1.0 OG A:SER564 4.3 77.9 1.0 OD2 A:ASP1336 4.3 79.0 1.0 CB A:GLN1256 4.4 73.5 1.0 OD1 A:ASP1336 4.5 79.0 1.0 O3G A:ATP1502 4.5 80.2 1.0 NE2 A:GLN1337 4.7 79.2 1.0 CG A:ASP1336 4.8 79.0 1.0 O2A A:ATP1502 4.9 80.2 1.0 CD A:GLN1337 5.0 79.2 1.0

Magnesium binding site 2 out of 2 in the Cryo-Em Structure of the Outward-Facing Plasmodium Falciparum Multidrug Resistance Protein 1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of the Outward-Facing Plasmodium Falciparum Multidrug Resistance Protein 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1504 b:66.8 occ:1.00 O2B A:ATP1501 2.0 66.8 1.0 OE1 A:GLN462 2.0 73.8 1.0 O3G A:ATP1501 2.1 66.8 1.0 CD A:GLN462 2.9 73.8 1.0 NE2 A:GLN462 3.2 73.8 1.0 PB A:ATP1501 3.3 66.8 1.0 PG A:ATP1501 3.4 66.8 1.0 O3B A:ATP1501 3.4 66.8 1.0 CB A:SER420 3.6 68.8 1.0 O3A A:ATP1501 4.1 66.8 1.0 O1G A:ATP1501 4.2 66.8 1.0 CG A:GLN462 4.3 73.8 1.0 OG A:SER420 4.4 68.8 1.0 O2G A:ATP1501 4.5 66.8 1.0 OD2 A:ASP587 4.5 77.0 1.0 O1B A:ATP1501 4.5 66.8 1.0 CB A:GLN462 4.6 73.8 1.0 N A:SER420 4.7 68.8 1.0 O1A A:ATP1501 4.7 66.8 1.0 OD1 A:ASP587 4.8 77.0 1.0 CA A:SER420 4.8 68.8 1.0 N A:GLY1314 4.9 65.0 1.0

K.Si, X.He, L.Chen, A.Zhang, C.Guo, M.Li. The Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Reveals An N-Terminal Regulatory Domain. Proc.Natl.Acad.Sci.Usa V. 120 05120 2023.
ISSN: ESSN 1091-6490
PubMed: 37527341
DOI: 10.1073/PNAS.2219905120