Magnesium in PDB 8k7b: Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound)

All present enzymatic activity of Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound):
7.6.2.5;

The structure of Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound) also contains other interesting chemical elements:

Vanadium

(V)

2 atoms

The binding sites of Magnesium atom in the Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound) (pdb code 8k7b). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound), PDB code: 8k7b:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg903 b:20.0 occ:1.00 O1G A:AOV902 1.8 30.0 1.0 OG A:SER630 1.9 74.4 1.0 OE1 A:GLN671 2.5 67.8 1.0 O1B A:AOV902 2.5 30.0 1.0 CB A:SER630 3.1 74.4 1.0 O2G A:AOV902 3.3 30.0 1.0 VG A:AOV902 3.4 30.0 1.0 CD A:GLN671 3.4 67.8 1.0 O3G A:AOV902 3.6 30.0 1.0 NE2 A:GLN671 3.8 67.8 1.0 PB A:AOV902 3.9 30.0 1.0 OD1 A:ASP751 4.0 78.8 1.0 N A:SER630 4.1 74.4 1.0 CA A:SER630 4.1 74.4 1.0 OD2 A:ASP751 4.4 78.8 1.0 O3B A:AOV902 4.5 30.0 1.0 O2B A:AOV902 4.6 30.0 1.0 CG A:ASP751 4.6 78.8 1.0 CG A:GLN671 4.8 67.8 1.0

Magnesium binding site 2 out of 2 in the Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound) within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg903 b:20.0 occ:1.00 O2G B:AOV902 1.8 30.0 1.0 OG B:SER630 2.0 73.0 1.0 O1B B:AOV902 2.7 30.0 1.0 NE2 B:GLN671 2.9 68.7 1.0 CB B:SER630 3.1 73.0 1.0 OE1 B:GLN671 3.1 68.7 1.0 CD B:GLN671 3.4 68.7 1.0 PB B:AOV902 3.8 30.0 1.0 VG B:AOV902 3.8 30.0 1.0 OD1 B:ASP751 3.9 78.6 1.0 O3B B:AOV902 3.9 30.0 1.0 O2B B:AOV902 4.2 30.0 1.0 CA B:SER630 4.4 73.0 1.0 N B:SER630 4.5 73.0 1.0 O1G B:AOV902 4.5 30.0 1.0 CG B:ASP751 4.7 78.6 1.0 OD2 B:ASP751 4.8 78.6 1.0 CG B:GLN671 4.8 68.7 1.0 O4G B:AOV902 4.8 30.0 1.0

S.S.Lee, J.G.Park, E.Jang, S.H.Choi, S.Kim, J.W.Kim, M.S.Jin. W546 Stacking Disruption Traps the Human Porphyrin Transporter ABCB6 in An Outward-Facing Transient State. Commun Biol V. 6 960 2023.
ISSN: ESSN 2399-3642
PubMed: 37735522
DOI: 10.1038/S42003-023-05339-3