Magnesium in PDB 8os1: X-Ray Structure of the Peroxisomal Targeting Signal 1 (PTS1) of Trypanosoma Cruzi PEX5 in Complex with the PTS1 Peptide

The structure of X-Ray Structure of the Peroxisomal Targeting Signal 1 (PTS1) of Trypanosoma Cruzi PEX5 in Complex with the PTS1 Peptide, PDB code: 8os1 was solved by V.Napolitano, A.Blat, G.M.Popowicz, G.Dubin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.22 / 2.10
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	129.331, 69.936, 71.106, 90, 100.05, 90
R / Rfree (%)	19.3 / 25.3

The binding sites of Magnesium atom in the X-Ray Structure of the Peroxisomal Targeting Signal 1 (PTS1) of Trypanosoma Cruzi PEX5 in Complex with the PTS1 Peptide (pdb code 8os1). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the X-Ray Structure of the Peroxisomal Targeting Signal 1 (PTS1) of Trypanosoma Cruzi PEX5 in Complex with the PTS1 Peptide, PDB code: 8os1:

Magnesium binding site 1 out of 1 in the X-Ray Structure of the Peroxisomal Targeting Signal 1 (PTS1) of Trypanosoma Cruzi PEX5 in Complex with the PTS1 Peptide


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of X-Ray Structure of the Peroxisomal Targeting Signal 1 (PTS1) of Trypanosoma Cruzi PEX5 in Complex with the PTS1 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg706 b:32.0 occ:1.00 OD1 B:ASN355 2.0 33.8 1.0 CG B:ASN355 3.1 29.7 1.0 ND2 B:ASN355 3.7 28.8 1.0 O B:HOH905 4.0 36.4 1.0 O B:HOH911 4.2 36.2 1.0 CB B:ASN355 4.3 28.8 1.0 O B:HOH845 4.4 33.9 1.0 CA B:ASN355 4.5 30.6 1.0 C B:ASN355 4.6 28.8 1.0 CD B:PRO357 4.7 26.4 1.0 N B:ASN356 4.8 29.0 1.0 O B:ASN355 4.9 30.2 1.0

M.Banasik, V.Napolitano, A.Blat, K.Abdulkarim, J.Plewka, C.Czaplewski, A.Gieldon, M.Kozak, B.Wladyka, G.Popowicz, G.Dubin. Structural Dynamics of the Tpr Domain of the Peroxisomal Cargo Receptor PEX5 in Trypanosoma. Int.J.Biol.Macromol. 35510 2024.
ISSN: ISSN 0141-8130
PubMed: 39304044
DOI: 10.1016/J.IJBIOMAC.2024.135510