Magnesium in PDB 8pnq: Influenza A/H7N9 Polymerase in Elongation State with Continuous Pol II PS5 Ctd Peptide Mimic Bound in Site 1A/2A

The binding sites of Magnesium atom in the Influenza A/H7N9 Polymerase in Elongation State with Continuous Pol II PS5 Ctd Peptide Mimic Bound in Site 1A/2A (pdb code 8pnq). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Influenza A/H7N9 Polymerase in Elongation State with Continuous Pol II PS5 Ctd Peptide Mimic Bound in Site 1A/2A, PDB code: 8pnq:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Influenza A/H7N9 Polymerase in Elongation State with Continuous Pol II PS5 Ctd Peptide Mimic Bound in Site 1A/2A


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Influenza A/H7N9 Polymerase in Elongation State with Continuous Pol II PS5 Ctd Peptide Mimic Bound in Site 1A/2A within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg802 b:52.5 occ:1.00 OD2 B:ASP305 1.9 63.4 1.0 O3' M:A18 2.1 74.2 1.0 O1A B:2KH801 2.1 75.5 1.0 OD1 B:ASP445 2.3 72.6 1.0 OD2 B:ASP445 2.6 57.8 1.0 OD2 B:ASP446 2.7 66.1 1.0 CG B:ASP445 2.8 59.7 1.0 CG B:ASP305 2.9 64.6 1.0 CG B:ASP446 3.2 69.6 1.0 PA B:2KH801 3.2 79.3 1.0 OD1 B:ASP446 3.2 61.5 1.0 OD1 B:ASP305 3.3 59.7 1.0 O2A B:2KH801 3.4 67.3 1.0 MG B:MG803 3.4 67.5 1.0 C3' M:A18 3.5 65.1 1.0 O5' B:2KH801 3.8 69.9 1.0 C5' B:2KH801 3.9 66.6 1.0 C4' M:A18 4.1 67.8 1.0 N B:ASP446 4.2 56.0 1.0 CB B:ASP305 4.3 58.9 1.0 CB B:ASP445 4.3 52.8 1.0 O2' M:A18 4.4 69.8 1.0 CB B:ASP446 4.4 63.4 1.0 C2' M:A18 4.5 68.9 1.0 C5' M:A18 4.5 67.2 1.0 O1B B:2KH801 4.6 75.2 1.0 CA B:ASP446 4.6 57.1 1.0 N3A B:2KH801 4.6 71.1 1.0 C B:ASP445 4.7 52.7 1.0 CA B:ASP305 4.9 55.0 1.0

Magnesium binding site 2 out of 2 in the Influenza A/H7N9 Polymerase in Elongation State with Continuous Pol II PS5 Ctd Peptide Mimic Bound in Site 1A/2A


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Influenza A/H7N9 Polymerase in Elongation State with Continuous Pol II PS5 Ctd Peptide Mimic Bound in Site 1A/2A within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg803 b:67.5 occ:1.00 OD1 B:ASP305 1.8 59.7 1.0 O1B B:2KH801 1.9 75.2 1.0 O1A B:2KH801 2.1 75.5 1.0 O B:ASN306 2.3 63.9 1.0 O2G B:2KH801 2.4 69.5 1.0 OD2 B:ASP445 2.5 57.8 1.0 CG B:ASP305 2.9 64.6 1.0 PB B:2KH801 2.9 64.3 1.0 PA B:2KH801 3.2 79.3 1.0 N3A B:2KH801 3.2 71.1 1.0 OD2 B:ASP305 3.3 63.4 1.0 PG B:2KH801 3.4 82.2 1.0 MG B:MG802 3.4 52.5 1.0 C B:ASN306 3.4 53.4 1.0 O3B B:2KH801 3.5 69.1 1.0 CG B:ASP445 3.7 59.7 1.0 NZ B:LYS481 3.8 60.1 1.0 N B:ASN306 3.8 58.4 1.0 O1G B:2KH801 3.9 78.5 1.0 O2A B:2KH801 4.2 67.3 1.0 CA B:ASN306 4.2 47.9 1.0 CB B:ASP305 4.2 58.9 1.0 O2B B:2KH801 4.2 63.5 1.0 O5' B:2KH801 4.3 69.9 1.0 C5' B:2KH801 4.3 66.6 1.0 OD1 B:ASP445 4.3 72.6 1.0 N B:THR307 4.4 49.5 1.0 CA B:THR307 4.6 55.6 1.0 C B:ASP305 4.6 53.0 1.0 O3G B:2KH801 4.7 68.8 1.0 CB B:ASP445 4.7 52.8 1.0 CB B:ASN306 4.8 48.3 1.0 N B:LYS308 4.9 55.8 1.0 CA B:ASP305 4.9 55.0 1.0 O3' M:A18 4.9 74.2 1.0 CB B:TRP309 4.9 56.0 1.0

T.Krischuns, B.Arragain, C.Isel, S.Paisant, M.Budt, T.Wolff, S.Cusack, N.Naffakh. The Host Rna Polymerase II C-Terminal Domain Is the Anchor For Replication of the Influenza Virus Genome. Nat Commun V. 15 1064 2024.
ISSN: ESSN 2041-1723
PubMed: 38316757
DOI: 10.1038/S41467-024-45205-2