Magnesium in PDB 8pwa: Crystal Structure of the Human METTL3-METTL14 in Complex with A Bisubstrate Analogue (BA4)

Enzymatic activity of Crystal Structure of the Human METTL3-METTL14 in Complex with A Bisubstrate Analogue (BA4)

All present enzymatic activity of Crystal Structure of the Human METTL3-METTL14 in Complex with A Bisubstrate Analogue (BA4):
2.1.1.348;

Protein crystallography data

The structure of Crystal Structure of the Human METTL3-METTL14 in Complex with A Bisubstrate Analogue (BA4), PDB code: 8pwa was solved by R.K.Bedi, M.Etheve-Quelquejeu, A.Caflisch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 44.54 / 2.10
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 63.89, 63.89, 225.18, 90, 90, 120
R / Rfree (%) 19.1 / 22.5

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of the Human METTL3-METTL14 in Complex with A Bisubstrate Analogue (BA4) (pdb code 8pwa). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the Human METTL3-METTL14 in Complex with A Bisubstrate Analogue (BA4), PDB code: 8pwa:

Magnesium binding site 1 out of 1 in 8pwa

Go back to Magnesium Binding Sites List in 8pwa
Magnesium binding site 1 out of 1 in the Crystal Structure of the Human METTL3-METTL14 in Complex with A Bisubstrate Analogue (BA4)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Human METTL3-METTL14 in Complex with A Bisubstrate Analogue (BA4) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg402

b:48.7
occ:1.00
 NE2 B:HIS336 2.2 58.7 1.0
CE1 B:HIS336 2.4 53.8 1.0
ND1 B:HIS332 2.7 63.3 1.0
OD2 B:ASP157 2.9 73.8 1.0
OD1 B:ASP157 3.1 64.1 1.0
CG B:ASP157 3.4 67.5 1.0
CG B:HIS332 3.4 53.4 1.0
CB B:HIS332 3.5 39.7 1.0
CD2 B:HIS336 3.5 49.8 1.0
ND1 B:HIS336 3.7 54.3 1.0
CE1 B:HIS332 3.7 63.0 1.0
CG B:HIS336 4.2 47.0 1.0
CA B:HIS332 4.2 39.0 1.0
CD2 B:HIS332 4.6 48.5 1.0
O B:HIS332 4.6 36.4 1.0
NE2 B:HIS332 4.7 55.6 1.0
C B:HIS332 4.8 38.5 1.0
CB B:ASP157 4.9 63.8 1.0

Reference:

R.K.Bedi, M.Etheve-Quelquejeu, A.Caflisch. Crystal Structure of the Human METTL3-METTL14 in Complex with A Bisubstrate Analogue (BA4) To Be Published.
Page generated: Fri Oct 4 16:16:50 2024

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