Magnesium in PDB 8q48: Outward-Facing, Closed Proteoliposome Complex I at 2.5 A. Initially Purified in Lmng.

All present enzymatic activity of Outward-Facing, Closed Proteoliposome Complex I at 2.5 A. Initially Purified in Lmng.:
1.6.5.3; 1.6.99.3; 7.1.1.2;

The structure of Outward-Facing, Closed Proteoliposome Complex I at 2.5 A. Initially Purified in Lmng. also contains other interesting chemical elements:

Iron	(Fe)	28 atoms
Potassium	(K)	1 atom
Zinc	(Zn)	2 atoms

The binding sites of Magnesium atom in the Outward-Facing, Closed Proteoliposome Complex I at 2.5 A. Initially Purified in Lmng. (pdb code 8q48). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Outward-Facing, Closed Proteoliposome Complex I at 2.5 A. Initially Purified in Lmng., PDB code: 8q48:

Magnesium binding site 1 out of 1 in the Outward-Facing, Closed Proteoliposome Complex I at 2.5 A. Initially Purified in Lmng.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Outward-Facing, Closed Proteoliposome Complex I at 2.5 A. Initially Purified in Lmng. within 5.0Å range: probe atom residue distance (Å) B Occ O:Mg402 b:58.9 occ:1.00 O1B O:DGT401 2.0 63.4 1.0 O1A O:DGT401 2.5 63.4 1.0 O1G O:DGT401 2.5 63.4 1.0 PB O:DGT401 3.2 63.4 1.0 PG O:DGT401 3.5 63.4 1.0 CB O:SER36 3.6 59.9 1.0 PA O:DGT401 3.6 63.4 1.0 O3B O:DGT401 3.6 63.4 1.0 OG O:SER36 3.7 59.9 1.0 O3A O:DGT401 3.8 63.4 1.0 OE1 O:GLU53 4.2 56.1 1.0 O2B O:DGT401 4.2 63.4 1.0 O3G O:DGT401 4.3 63.4 1.0 O2A O:DGT401 4.5 63.4 1.0 O2G O:DGT401 4.6 63.4 1.0 C5' O:DGT401 4.6 63.4 1.0 O5' O:DGT401 4.7 63.4 1.0 CA O:SER36 4.7 59.9 1.0 N O:SER36 4.7 59.9 1.0 OE1 O:GLU125 4.8 56.9 1.0

D.N.Grba, J.J.Wright, W.Fisher, Z.Yin, J.Hirst. Molecular Mechanism of the Ischemia-Induced Regulatory Switch in Mammalian Complex I Science 2024.
ISSN: ESSN 1095-9203
DOI: 10.1126/SCIENCE.ADO2075