Magnesium in PDB 8q65: Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form

All present enzymatic activity of Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form:
1.1.1.205;

The binding sites of Magnesium atom in the Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form (pdb code 8q65). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form, PDB code: 8q65:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg602 b:130.7 occ:1.00 O2G A:ATP600 2.0 133.8 1.0 O1G A:ATP601 2.0 141.0 1.0 OE2 A:GLU200 2.3 133.4 1.0 MG A:MG603 2.5 137.8 1.0 PG A:ATP600 2.7 132.4 1.0 O3B A:ATP600 2.8 130.3 1.0 O3G E:ATP600 2.8 130.0 1.0 OE1 A:GLU200 2.9 134.9 1.0 CD A:GLU200 2.9 132.2 1.0 O3G A:ATP600 3.1 127.9 1.0 PG A:ATP601 3.4 145.8 1.0 O1B A:ATP601 3.7 141.5 1.0 O2G A:ATP601 3.8 140.2 1.0 O1B A:ATP600 3.9 133.5 1.0 PB A:ATP600 4.0 132.1 1.0 NH2 E:ARG157 4.0 126.2 1.0 PG E:ATP600 4.1 129.3 1.0 O3B A:ATP601 4.1 143.5 1.0 O1G A:ATP600 4.1 126.0 1.0 MG E:MG602 4.2 115.8 1.0 PB A:ATP601 4.3 148.8 1.0 CG A:GLU200 4.4 128.4 1.0 O2G E:ATP600 4.5 125.7 1.0 O3G A:ATP601 4.5 141.9 1.0 O1G E:ATP600 4.6 120.2 1.0 O2B A:ATP601 4.7 142.3 1.0 NH2 A:ARG157 4.8 120.5 1.0 O2B A:ATP600 4.9 128.0 1.0 CZ E:ARG157 4.9 120.8 1.0 NE E:ARG157 4.9 118.7 1.0

Magnesium binding site 2 out of 4 in the Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg603 b:137.8 occ:1.00 O1B A:ATP601 1.9 141.5 1.0 O2G A:ATP600 2.0 133.8 1.0 MG A:MG602 2.5 130.7 1.0 PB A:ATP601 2.5 148.8 1.0 O1G A:ATP601 2.6 141.0 1.0 O2B A:ATP601 2.7 142.3 1.0 O3B A:ATP600 2.9 130.3 1.0 PG A:ATP600 2.9 132.4 1.0 O1B A:ATP600 3.1 133.5 1.0 PB A:ATP600 3.2 132.1 1.0 O3B A:ATP601 3.2 143.5 1.0 O2B A:ATP600 3.5 128.0 1.0 PG A:ATP601 3.5 145.8 1.0 O1G A:ATP600 3.6 126.0 1.0 OE1 A:GLU200 3.8 134.9 1.0 OE2 A:GLU200 4.0 133.4 1.0 O3A A:ATP601 4.0 146.7 1.0 O3G A:ATP600 4.2 127.9 1.0 CD A:GLU200 4.2 132.2 1.0 O2G A:ATP601 4.4 140.2 1.0 CB A:SER139 4.5 132.5 1.0 O3G A:ATP601 4.7 141.9 1.0 OG A:SER139 4.8 134.6 1.0 O3A A:ATP600 4.8 128.8 1.0 O1A A:ATP601 4.9 139.2 1.0

Magnesium binding site 3 out of 4 in the Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg602 b:115.8 occ:1.00 O2G E:ATP600 2.3 125.7 1.0 O1G E:ATP601 2.6 119.8 1.0 OE2 E:GLU200 2.7 124.0 1.0 O3G A:ATP600 2.9 127.9 1.0 MG E:MG603 3.1 119.2 1.0 OE1 E:GLU200 3.2 120.2 1.0 CD E:GLU200 3.3 121.7 1.0 PG E:ATP600 3.4 129.3 1.0 O3G E:ATP600 3.5 130.0 1.0 O2G A:ATP600 3.6 133.8 1.0 O2G E:ATP601 3.6 118.2 1.0 PG E:ATP601 3.6 126.3 1.0 PG A:ATP600 3.7 132.4 1.0 NH2 A:ARG157 4.1 120.5 1.0 MG A:MG602 4.2 130.7 1.0 O3B E:ATP600 4.3 125.7 1.0 O1G A:ATP600 4.4 126.0 1.0 O1G E:ATP600 4.6 120.2 1.0 O3B E:ATP601 4.6 122.2 1.0 O1B E:ATP600 4.6 126.7 1.0 O3G E:ATP601 4.8 127.5 1.0 CG E:GLU200 4.8 118.0 1.0 NE A:ARG157 4.9 118.2 1.0 NH1 A:ARG160 4.9 113.9 1.0 O2B E:ATP601 4.9 126.0 1.0 CZ A:ARG157 5.0 118.9 1.0

Magnesium binding site 4 out of 4 in the Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Atp-Bound Form within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg603 b:119.2 occ:1.00 OE1 E:GLU200 2.1 120.2 1.0 O1B E:ATP600 2.2 126.7 1.0 O2G E:ATP600 2.2 125.7 1.0 O1B E:ATP601 2.6 125.6 1.0 O2B E:ATP601 3.1 126.0 1.0 PB E:ATP601 3.1 127.1 1.0 MG E:MG602 3.1 115.8 1.0 O1G E:ATP601 3.2 119.8 1.0 CD E:GLU200 3.3 121.7 1.0 PB E:ATP600 3.3 127.2 1.0 NZ E:LYS201 3.3 119.4 1.0 PG E:ATP600 3.4 129.3 1.0 O3B E:ATP600 3.4 125.7 1.0 O3B E:ATP601 3.6 122.2 1.0 OE2 E:GLU200 3.8 124.0 1.0 PG E:ATP601 3.9 126.3 1.0 OG E:SER139 4.0 125.9 1.0 O2G E:ATP601 4.1 118.2 1.0 O2B E:ATP600 4.1 128.3 1.0 O1G E:ATP600 4.3 120.2 1.0 CG E:GLU200 4.4 118.0 1.0 CB E:GLU200 4.5 115.7 1.0 O3A E:ATP600 4.5 124.9 1.0 O3G E:ATP600 4.5 130.0 1.0 O3A E:ATP601 4.7 123.2 1.0 CE E:LYS201 4.7 119.8 1.0 NH2 A:ARG157 4.7 120.5 1.0 O1A E:ATP600 4.8 122.3 1.0

O.Bulvas, T.Kouba, I.Pichova. Mycobacterium Smegmatis Inosine Monophosphate Dehydrogenase (Impdh) Apo Form To Be Published.
DOI: 10.1038/S41467-024-50933-6