Magnesium in PDB 8s3e: Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26

The structure of Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 also contains other interesting chemical elements:

Potassium	(K)	4 atoms
Calcium	(Ca)	8 atoms

The binding sites of Magnesium atom in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 (pdb code 8s3e). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26, PDB code: 8s3e:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1215 b:48.7 occ:1.00 OE2 A:GLU374 2.5 63.0 1.0 OE2 A:GLU399 2.6 69.5 1.0 CD A:GLU399 3.6 67.4 1.0 CD A:GLU374 3.7 69.3 1.0 CG A:GLU399 3.9 60.2 1.0 OE1 A:GLU374 4.3 78.4 1.0 O A:THR396 4.3 56.4 1.0 OD1 D:ASN172 4.4 78.3 1.0 ND2 D:ASN172 4.4 68.3 1.0 O A:PHE395 4.6 51.2 1.0 OE1 A:GLU399 4.6 73.1 1.0 C A:THR396 4.7 51.0 1.0 CA A:THR396 4.8 49.9 1.0 CG D:ASN172 4.9 77.1 1.0 CG A:GLU374 4.9 52.2 1.0

Magnesium binding site 2 out of 4 in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1201 b:48.7 occ:1.00 OE2 B:GLU399 2.5 69.5 1.0 OE2 B:GLU374 2.7 63.0 1.0 CD B:GLU399 3.5 67.4 1.0 CG B:GLU399 3.8 60.2 1.0 CD B:GLU374 3.9 69.3 1.0 OD1 A:ASN172 4.4 78.3 1.0 ND2 A:ASN172 4.4 68.3 1.0 OE1 B:GLU374 4.4 78.4 1.0 O B:THR396 4.5 56.4 1.0 O B:PHE395 4.5 51.2 1.0 OE1 B:GLU399 4.6 73.1 1.0 C B:THR396 4.8 51.0 1.0 CA B:THR396 4.9 49.9 1.0 CG A:ASN172 4.9 77.1 1.0

Magnesium binding site 3 out of 4 in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg1201 b:48.7 occ:1.00 OE2 C:GLU399 2.5 69.5 1.0 OE2 C:GLU374 2.5 63.0 1.0 CD C:GLU399 3.4 67.4 1.0 CD C:GLU374 3.7 69.3 1.0 CG C:GLU399 3.8 60.2 1.0 OE1 C:GLU374 4.2 78.4 1.0 OD1 B:ASN172 4.4 78.3 1.0 ND2 B:ASN172 4.4 68.3 1.0 O C:THR396 4.4 56.4 1.0 OE1 C:GLU399 4.5 73.1 1.0 O C:PHE395 4.6 51.2 1.0 C C:THR396 4.8 51.0 1.0 CG C:GLU374 4.8 52.2 1.0 CG B:ASN172 4.9 77.1 1.0 CA C:THR396 4.9 49.9 1.0

Magnesium binding site 4 out of 4 in the Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Structure of Rabbit SLO1 in Complex with GAMMA1/LRRC26 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg1201 b:48.7 occ:1.00 OE2 D:GLU374 2.3 63.0 1.0 OE2 D:GLU399 2.5 69.5 1.0 CD D:GLU374 3.4 69.3 1.0 CD D:GLU399 3.5 67.4 1.0 CG D:GLU399 3.8 60.2 1.0 OE1 D:GLU374 4.0 78.4 1.0 O D:THR396 4.3 56.4 1.0 OD1 C:ASN172 4.4 78.3 1.0 ND2 C:ASN172 4.4 68.3 1.0 OE1 D:GLU399 4.6 73.1 1.0 CG D:GLU374 4.6 52.2 1.0 O D:PHE395 4.7 51.2 1.0 C D:THR396 4.7 51.0 1.0 CG C:ASN172 4.9 77.1 1.0 CA D:THR396 4.9 49.9 1.0

M.Redhardt, S.Raunser, T.Raisch. Cryo-Em Structure of the SLO1 Potassium Channel with the Auxiliary Gamma 1 Subunit Suggests A Mechanism For Depolarization-Independent Activation. Febs Lett. 2024.
ISSN: ISSN 0014-5793
PubMed: 38553946
DOI: 10.1002/1873-3468.14863