Magnesium in PDB 8sqk: Sars-Cov-2 Replication-Transcription Complex Bound to Rna-NSP9 and Gdp-Betas, As A Pre-Catalytic Dernaylation/Mrna Capping Intermediate

Enzymatic activity of Sars-Cov-2 Replication-Transcription Complex Bound to Rna-NSP9 and Gdp-Betas, As A Pre-Catalytic Dernaylation/Mrna Capping Intermediate

All present enzymatic activity of Sars-Cov-2 Replication-Transcription Complex Bound to Rna-NSP9 and Gdp-Betas, As A Pre-Catalytic Dernaylation/Mrna Capping Intermediate:
2.7.7.48;

Other elements in 8sqk:

The structure of Sars-Cov-2 Replication-Transcription Complex Bound to Rna-NSP9 and Gdp-Betas, As A Pre-Catalytic Dernaylation/Mrna Capping Intermediate also contains other interesting chemical elements:

Zinc (Zn) 2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Sars-Cov-2 Replication-Transcription Complex Bound to Rna-NSP9 and Gdp-Betas, As A Pre-Catalytic Dernaylation/Mrna Capping Intermediate (pdb code 8sqk). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Sars-Cov-2 Replication-Transcription Complex Bound to Rna-NSP9 and Gdp-Betas, As A Pre-Catalytic Dernaylation/Mrna Capping Intermediate, PDB code: 8sqk:

Magnesium binding site 1 out of 1 in 8sqk

Go back to Magnesium Binding Sites List in 8sqk
Magnesium binding site 1 out of 1 in the Sars-Cov-2 Replication-Transcription Complex Bound to Rna-NSP9 and Gdp-Betas, As A Pre-Catalytic Dernaylation/Mrna Capping Intermediate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Sars-Cov-2 Replication-Transcription Complex Bound to Rna-NSP9 and Gdp-Betas, As A Pre-Catalytic Dernaylation/Mrna Capping Intermediate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1005

b:43.2
occ:1.00
O2B A:VSN1002 2.3 59.5 1.0
OD1 A:ASN209 2.4 42.6 1.0
OP2 O:A1 2.7 59.1 1.0
OD2 A:ASP218 2.8 44.0 1.0
OD2 A:ASP208 3.3 47.7 1.0
PB A:VSN1002 3.4 83.1 1.0
CG A:ASN209 3.5 34.3 1.0
HD21 A:ASN209 3.5 40.0 1.0
OP3 A:VSN1002 3.7 63.2 1.0
CG A:ASP218 3.9 47.3 1.0
OP1 A:VSN1002 3.9 53.7 1.0
ND2 A:ASN209 3.9 38.3 1.0
S1B A:VSN1002 3.9 60.2 1.0
HB2 A:ASP218 4.0 45.2 1.0
O A:HOH1113 4.0 33.9 1.0
H5'' O:A1 4.2 56.4 1.0
P O:A1 4.2 80.8 1.0
HB3 A:ASP218 4.2 45.4 1.0
CG A:ASP208 4.3 40.9 1.0
CB A:ASP218 4.3 45.9 1.0
P A:VSN1002 4.3 63.0 1.0
O A:ASP208 4.4 38.4 1.0
O3' A:VSN1002 4.4 53.7 1.0
HA A:ASN209 4.6 39.4 1.0
H4' A:VSN1002 4.6 54.2 1.0
HD1 A:PHE35 4.6 45.6 1.0
O5' A:VSN1002 4.6 60.6 1.0
HG1 A:THR206 4.6 39.0 1.0
O5' O:A1 4.6 61.9 1.0
O A:HOH1160 4.7 33.1 1.0
O3B A:VSN1002 4.7 57.9 1.0
HE1 A:PHE35 4.8 45.7 1.0
HD22 A:ASN209 4.8 39.9 1.0
O A:HOH1197 4.8 35.7 1.0
CB A:ASN209 4.8 32.6 1.0
OD1 A:ASP208 4.8 39.7 1.0
C A:ASP208 4.9 34.3 1.0
HO3' A:VSN1002 4.9 52.4 1.0
C5' O:A1 4.9 57.5 1.0
HE1 A:TYR217 4.9 40.9 1.0
OD1 A:ASP218 4.9 47.6 1.0
HB2 A:ASP208 5.0 41.6 1.0

Reference:

G.I.Small, O.Fedorova, P.D.B.Olinares, J.Chandanani, A.Banerjee, Y.J.Choi, H.Molina, B.T.Chait, S.A.Darst, E.A.Campbell. Structural and Functional Insights Into the Enzymatic Plasticity of the Sars-Cov-2 Niran Domain. Mol.Cell V. 83 3921 2023.
ISSN: ISSN 1097-2765
PubMed: 37890482
DOI: 10.1016/J.MOLCEL.2023.10.001
Page generated: Fri Oct 4 19:58:36 2024

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