Magnesium in PDB 8sxt: Structure of Line-1 ORF2P with Template:Primer Hybrid

All present enzymatic activity of Structure of Line-1 ORF2P with Template:Primer Hybrid:
2.7.7.49;

The binding sites of Magnesium atom in the Structure of Line-1 ORF2P with Template:Primer Hybrid (pdb code 8sxt). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of Line-1 ORF2P with Template:Primer Hybrid, PDB code: 8sxt:

Magnesium binding site 1 out of 1 in the Structure of Line-1 ORF2P with Template:Primer Hybrid


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Line-1 ORF2P with Template:Primer Hybrid within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1301 b:103.5 occ:1.00 O A:ALA601 2.0 117.3 1.0 OD1 A:ASP600 2.6 122.8 1.0 C A:ALA601 2.8 110.9 1.0 O1B C:TTP101 2.9 122.7 1.0 N A:ALA601 2.9 112.8 1.0 O1A C:TTP101 3.0 122.4 1.0 CG A:ASP600 3.1 125.7 1.0 CA A:ALA601 3.2 107.8 1.0 OD2 A:ASP600 3.3 121.9 1.0 CB A:ALA601 3.4 110.2 1.0 C A:ASP600 3.7 122.9 1.0 OD2 A:ASP702 3.7 92.7 1.0 CB A:ASP702 3.7 82.9 1.0 N A:GLU602 4.0 106.3 1.0 CG A:ASP702 4.1 85.2 1.0 CA A:ASP600 4.2 120.0 1.0 PB C:TTP101 4.2 130.4 1.0 CB A:ASP600 4.2 124.2 1.0 PA C:TTP101 4.4 124.9 1.0 O A:ASP600 4.5 122.1 1.0 CA A:GLU602 4.7 110.8 1.0 O3A C:TTP101 4.7 130.4 1.0 O3B C:TTP101 4.8 129.6 1.0 N A:LYS603 4.9 95.7 1.0

E.T.Baldwin, T.Van Eeuwen, D.Hoyos, A.Zalevsky, E.P.Tchesnokov, R.Sanchez, B.D.Miller, L.H.Di Stefano, F.X.Ruiz, M.Hancock, E.Isik, C.Mendez-Dorantes, T.Walpole, C.Nichols, P.Wan, K.Riento, R.Halls-Kass, M.Augustin, A.Lammens, A.Jestel, P.Upla, K.Xibinaku, S.Congreve, M.Hennink, K.B.Rogala, A.M.Schneider, J.E.Fairman, S.M.Christensen, B.Desrosiers, G.S.Bisacchi, O.L.Saunders, N.Hafeez, W.Miao, R.Kapeller, D.M.Zaller, A.Sali, O.Weichenrieder, K.H.Burns, M.Gotte, M.P.Rout, E.Arnold, B.D.Greenbaum, D.L.Romero, J.Lacava, M.S.Taylor. Structures, Functions, and Adaptations of the Human Line-1 ORF2 Protein. Nature 2023.
ISSN: ESSN 1476-4687
PubMed: 38096902
DOI: 10.1038/S41586-023-06947-Z