Magnesium in PDB 8tlg: CDCA7 (Mouse) Binds Non-B-Form 34-Mer Dna Oligo

The structure of CDCA7 (Mouse) Binds Non-B-Form 34-Mer Dna Oligo, PDB code: 8tlg was solved by J.R.Horton, R.Ren, X.Cheng, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.28 / 2.09
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	86.491, 60.562, 53.229, 90, 123.1, 90
R / Rfree (%)	18.6 / 22.3

The structure of CDCA7 (Mouse) Binds Non-B-Form 34-Mer Dna Oligo also contains other interesting chemical elements:

Zinc

(Zn)

3 atoms

The binding sites of Magnesium atom in the CDCA7 (Mouse) Binds Non-B-Form 34-Mer Dna Oligo (pdb code 8tlg). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the CDCA7 (Mouse) Binds Non-B-Form 34-Mer Dna Oligo, PDB code: 8tlg:

Magnesium binding site 1 out of 1 in the CDCA7 (Mouse) Binds Non-B-Form 34-Mer Dna Oligo


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of CDCA7 (Mouse) Binds Non-B-Form 34-Mer Dna Oligo within 5.0Å range: probe atom residue distance (Å) B Occ X:Mg103 b:60.0 occ:0.50 OP1 X:DG20 2.1 55.1 1.0 O A:HOH506 2.3 47.8 1.0 P X:DG20 3.5 44.2 1.0 O A:HOH514 3.7 60.3 1.0 N A:MET244 3.9 83.0 1.0 OG1 A:THR245 4.1 58.3 1.0 O3' X:DA19 4.3 46.4 1.0 OP2 X:DG20 4.4 47.8 1.0 O5' X:DG20 4.5 41.4 1.0 C5' X:DG20 4.5 39.3 1.0 CA A:MET244 4.9 82.2 1.0 N A:THR245 5.0 68.6 1.0

S.Hardikar, R.Ren, Z.Ying, J.R.Horton, M.D.Bramble, B.Liu, Y.Lu, J.Dan, X.Zhang, X.Cheng, T.Chen. The Icf Syndrome Protein CDCA7 Harbors A Unique Dna-Binding Domain That Recognizes A Cpg Dyad in the Context of A Non-B Dna Sci Adv 2024.
ISSN: ESSN 2375-2548