Magnesium in PDB 8txk: Kras 1-169 G12C Mutant at 240K

All present enzymatic activity of Kras 1-169 G12C Mutant at 240K:
3.6.5.2;

The structure of Kras 1-169 G12C Mutant at 240K, PDB code: 8txk was solved by S.L.Deck, M.Xu, S.K.Milano, C.Aplin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.24 / 1.38
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	39.322, 42.368, 93.405, 90, 90, 90
R / Rfree (%)	19.5 / 22.1

The binding sites of Magnesium atom in the Kras 1-169 G12C Mutant at 240K (pdb code 8txk). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Kras 1-169 G12C Mutant at 240K, PDB code: 8txk:

Magnesium binding site 1 out of 1 in the Kras 1-169 G12C Mutant at 240K


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Kras 1-169 G12C Mutant at 240K within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg202 b:13.1 occ:1.00 O A:HOH351 2.0 13.6 1.0 O1B A:GDP201 2.0 13.1 1.0 O A:HOH322 2.1 12.5 1.0 O A:HOH315 2.1 14.6 1.0 OG A:SER17 2.1 13.6 1.0 O A:HOH329 2.1 12.1 1.0 CB A:SER17 3.2 14.2 1.0 PB A:GDP201 3.3 12.0 1.0 O3B A:GDP201 3.6 12.7 1.0 N A:SER17 3.9 12.1 1.0 OD2 A:ASP57 4.1 14.3 1.0 O2A A:GDP201 4.1 16.6 1.0 CA A:SER17 4.2 13.4 1.0 OD1 A:ASP57 4.2 12.2 1.0 O A:ASP33 4.3 17.3 1.0 O A:PRO34 4.3 17.2 1.0 O2B A:GDP201 4.3 11.9 1.0 CA A:PRO34 4.3 17.6 1.0 O3A A:GDP201 4.3 13.4 1.0 CD2 A:TYR32 4.4 21.8 1.0 O A:ILE36 4.5 16.8 1.0 CG A:ASP57 4.6 13.0 1.0 PA A:GDP201 4.6 14.1 1.0 O A:THR58 4.6 13.1 1.0 C A:PRO34 4.6 16.9 1.0 CE2 A:TYR32 4.6 22.3 1.0 O1A A:GDP201 4.7 15.2 1.0 CB A:LYS16 4.9 11.6 1.0 O A:TYR32 4.9 20.6 1.0 NZ A:LYS16 5.0 11.8 1.0

S.L.Deck, M.Xu, C.Aplin, S.K.Milano. Temperature Gradient Structures of Oncogenic Kras G12C Mutants To Be Published.