Magnesium in PDB 8ty8: Kras 1-169 G12C Mutant at 310K

All present enzymatic activity of Kras 1-169 G12C Mutant at 310K:
3.6.5.2;

The structure of Kras 1-169 G12C Mutant at 310K, PDB code: 8ty8 was solved by S.L.Deck, M.Xu, S.K.Milano, C.Aplin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.24 / 1.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	39.424, 41.809, 92.088, 90, 90, 90
R / Rfree (%)	18.2 / 20.6

The binding sites of Magnesium atom in the Kras 1-169 G12C Mutant at 310K (pdb code 8ty8). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Kras 1-169 G12C Mutant at 310K, PDB code: 8ty8:

Magnesium binding site 1 out of 1 in the Kras 1-169 G12C Mutant at 310K


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Kras 1-169 G12C Mutant at 310K within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg202 b:16.7 occ:1.00 O A:HOH337 2.0 16.8 1.0 O1B A:GDP201 2.0 15.5 1.0 O A:HOH331 2.1 19.2 1.0 O A:HOH327 2.1 18.6 1.0 OG A:SER17 2.1 18.2 1.0 O A:HOH322 2.2 17.3 1.0 CB A:SER17 3.2 19.3 1.0 PB A:GDP201 3.3 16.1 1.0 O3B A:GDP201 3.5 16.9 1.0 N A:SER17 3.9 16.5 1.0 OD2 A:ASP57 4.1 18.6 1.0 CA A:SER17 4.1 16.8 1.0 O2A A:GDP201 4.1 19.3 1.0 OD1 A:ASP57 4.3 17.3 1.0 O A:ASP33 4.3 23.7 1.0 CD1 A:TYR32 4.3 26.2 1.0 O2B A:GDP201 4.3 16.3 1.0 O3A A:GDP201 4.3 17.4 1.0 O A:PRO34 4.3 22.0 1.0 CA A:PRO34 4.4 22.9 1.0 O A:ILE36 4.4 21.7 1.0 PA A:GDP201 4.6 18.2 1.0 CE1 A:TYR32 4.6 26.9 1.0 CG A:ASP57 4.6 17.0 1.0 O A:THR58 4.6 18.4 1.0 O1A A:GDP201 4.7 19.1 1.0 C A:PRO34 4.7 22.5 1.0 CB A:LYS16 4.9 16.6 1.0 O A:TYR32 5.0 27.7 1.0 O A:HOH328 5.0 25.8 1.0 CE A:LYS16 5.0 16.8 1.0 NZ A:LYS16 5.0 16.7 1.0 C A:LYS16 5.0 17.2 1.0

S.L.Deck, M.Xu, C.Aplin, S.K.Milano. Temperature Gradient Structures of Oncogenic Kras G12C Mutants To Be Published.