Magnesium in PDB 8tzg: Structure of C-Terminal LRRK2 Bound to Mli-2 (I2020T Mutant)

All present enzymatic activity of Structure of C-Terminal LRRK2 Bound to Mli-2 (I2020T Mutant):
2.7.11.1;

The binding sites of Magnesium atom in the Structure of C-Terminal LRRK2 Bound to Mli-2 (I2020T Mutant) (pdb code 8tzg). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of C-Terminal LRRK2 Bound to Mli-2 (I2020T Mutant), PDB code: 8tzg:

Magnesium binding site 1 out of 1 in the Structure of C-Terminal LRRK2 Bound to Mli-2 (I2020T Mutant)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of C-Terminal LRRK2 Bound to Mli-2 (I2020T Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2603 b:60.9 occ:1.00 O1B A:GDP2602 2.1 121.2 1.0 OG1 A:THR1348 2.3 81.9 1.0 CB A:THR1348 3.3 81.9 1.0 PB A:GDP2602 3.5 121.2 1.0 N A:THR1368 3.5 83.1 1.0 CG2 A:THR1368 3.6 83.1 1.0 O1A A:GDP2602 3.8 121.2 1.0 O2B A:GDP2602 3.9 121.2 1.0 CG2 A:THR1348 4.0 81.9 1.0 O3A A:GDP2602 4.1 121.2 1.0 OD2 A:ASP1394 4.1 66.2 1.0 CA A:THR1368 4.4 83.1 1.0 O A:PHE1395 4.5 62.5 1.0 CB A:THR1368 4.5 83.1 1.0 O3B A:GDP2602 4.6 121.2 1.0 CA A:THR1348 4.6 81.9 1.0 PA A:GDP2602 4.6 121.2 1.0 CG A:ASP1394 4.6 66.2 1.0 OD1 A:ASP1394 4.7 66.2 1.0 OD2 A:ASP1372 4.7 69.7 1.0 N A:THR1348 4.8 81.9 1.0 OG1 A:THR1368 5.0 83.1 1.0

M.Sanz Murillo, A.Villagran Suarez, V.Dederer, D.Chatterjee, J.Alegrio Louro, S.Knapp, S.Mathea, A.E.Leschziner. Inhibition of Parkinson'S Disease-Related LRRK2 By Type I and Type II Kinase Inhibitors: Activity and Structures. Sci Adv V. 9 K6191 2023.
ISSN: ESSN 2375-2548
PubMed: 38039358
DOI: 10.1126/SCIADV.ADK6191