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Atomistry » Magnesium » PDB 8tj0-8unh » 8u6j » |
Magnesium in PDB 8u6j: Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with N-(2- (5-Chloro-2-((2-Cyanoindolizin-8-Yl)Oxy)Phenoxy)Ethyl)-N- Methylacrylamide (JLJ746), A Non-Nucleoside InhibitorEnzymatic activity of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with N-(2- (5-Chloro-2-((2-Cyanoindolizin-8-Yl)Oxy)Phenoxy)Ethyl)-N- Methylacrylamide (JLJ746), A Non-Nucleoside Inhibitor
All present enzymatic activity of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with N-(2- (5-Chloro-2-((2-Cyanoindolizin-8-Yl)Oxy)Phenoxy)Ethyl)-N- Methylacrylamide (JLJ746), A Non-Nucleoside Inhibitor:
2.7.7.49; 2.7.7.7; 3.1.26.13; Protein crystallography data
The structure of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with N-(2- (5-Chloro-2-((2-Cyanoindolizin-8-Yl)Oxy)Phenoxy)Ethyl)-N- Methylacrylamide (JLJ746), A Non-Nucleoside Inhibitor, PDB code: 8u6j
was solved by
G.Prucha,
S.Henry,
W.L.Jorgensen,
K.S.Anderson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8u6j:
The structure of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with N-(2- (5-Chloro-2-((2-Cyanoindolizin-8-Yl)Oxy)Phenoxy)Ethyl)-N- Methylacrylamide (JLJ746), A Non-Nucleoside Inhibitor also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with N-(2- (5-Chloro-2-((2-Cyanoindolizin-8-Yl)Oxy)Phenoxy)Ethyl)-N- Methylacrylamide (JLJ746), A Non-Nucleoside Inhibitor
(pdb code 8u6j). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with N-(2- (5-Chloro-2-((2-Cyanoindolizin-8-Yl)Oxy)Phenoxy)Ethyl)-N- Methylacrylamide (JLJ746), A Non-Nucleoside Inhibitor, PDB code: 8u6j: Magnesium binding site 1 out of 1 in 8u6jGo back to Magnesium Binding Sites List in 8u6j
Magnesium binding site 1 out
of 1 in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with N-(2- (5-Chloro-2-((2-Cyanoindolizin-8-Yl)Oxy)Phenoxy)Ethyl)-N- Methylacrylamide (JLJ746), A Non-Nucleoside Inhibitor
Mono view Stereo pair view
Reference:
G.R.Prucha,
S.Henry,
K.Hollander,
Z.J.Carter,
K.A.Spasov,
W.L.Jorgensen,
K.S.Anderson.
Covalent and Noncovalent Strategies For Targeting LYS102 in Hiv-1 Reverse Transcriptase. Eur.J.Med.Chem. V. 262 15894 2023.
Page generated: Thu Dec 28 10:34:52 2023
ISSN: ISSN 0223-5234 PubMed: 37883896 DOI: 10.1016/J.EJMECH.2023.115894 |
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