Magnesium in PDB 8uku: Rna Polymerase II Elongation Complex with Fapy-Dg Lesion with Cmp Added

Enzymatic activity of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion with Cmp Added

All present enzymatic activity of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion with Cmp Added:
2.7.7.6;

Protein crystallography data

The structure of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion with Cmp Added, PDB code: 8uku was solved by P.Hou, J.Oh, D.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.24 / 3.60
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 166.103, 224.009, 192.541, 90, 99.98, 90
R / Rfree (%) 25.8 / 30.2

Other elements in 8uku:

The structure of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion with Cmp Added also contains other interesting chemical elements:

Zinc (Zn) 8 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion with Cmp Added (pdb code 8uku). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion with Cmp Added, PDB code: 8uku:

Magnesium binding site 1 out of 1 in 8uku

Go back to Magnesium Binding Sites List in 8uku
Magnesium binding site 1 out of 1 in the Rna Polymerase II Elongation Complex with Fapy-Dg Lesion with Cmp Added


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Rna Polymerase II Elongation Complex with Fapy-Dg Lesion with Cmp Added within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1803

b:184.4
occ:1.00
 OD1 A:ASP483 2.0 184.2 1.0
P R:C10 2.3 170.6 1.0
O3' R:G9 2.4 139.4 1.0
OP1 R:C10 2.4 179.9 1.0
OP2 R:C10 2.4 137.0 1.0
CG A:ASP483 2.6 176.5 1.0
OD1 A:ASP485 2.7 102.8 1.0
OD2 A:ASP483 2.8 155.1 1.0
O A:ASP483 3.4 126.8 1.0
C3' R:G9 3.6 120.8 1.0
CG A:ASP485 3.7 105.2 1.0
C4' R:G9 3.9 134.8 1.0
NZ B:LYS987 3.9 115.6 1.0
O5' R:C10 3.9 143.8 1.0
O5' R:G9 3.9 129.9 1.0
C5' R:G9 3.9 155.6 1.0
CB A:ASP483 3.9 159.7 1.0
OD2 A:ASP485 4.1 102.7 1.0
C A:ASP483 4.1 104.0 1.0
CB A:ASP481 4.1 114.0 1.0
CA A:ASP483 4.4 117.3 1.0
OD2 A:ASP481 4.4 138.1 1.0
N A:ASP483 4.5 99.8 1.0
O A:ASP481 4.7 133.4 1.0
O2' R:G9 4.7 125.3 1.0
CG A:ASP481 4.7 142.2 1.0
C2' R:G9 4.7 122.4 1.0
N A:ASP485 4.8 99.7 1.0
C5' R:C10 4.8 178.3 1.0
C A:ASP481 4.9 136.4 1.0
CB A:ASP485 5.0 127.8 1.0

Reference:

S.Gao, P.Hou, J.Oh, D.Wang, M.M.Greenberg. Molecular Mechanism of Rna Polymerase II Transcriptional Mutagenesis By the Epimerizable Dna Lesion, Fapy·Dg. J.Am.Chem.Soc. V. 146 6274 2024.
ISSN: ESSN 1520-5126
PubMed: 38393762
DOI: 10.1021/JACS.3C14476
Page generated: Fri Oct 4 21:21:53 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy