Magnesium in PDB 8v7i: Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 1 Mm MG2+ For 1800S

All present enzymatic activity of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 1 Mm MG2+ For 1800S:
2.7.7.7;

The structure of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 1 Mm MG2+ For 1800S, PDB code: 8v7i was solved by C.Chang, Y.Gao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.67 / 1.72
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	98.547, 98.547, 81.894, 90, 90, 120
R / Rfree (%)	21.2 / 23.3

The binding sites of Magnesium atom in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 1 Mm MG2+ For 1800S (pdb code 8v7i). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 1 Mm MG2+ For 1800S, PDB code: 8v7i:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 1 Mm MG2+ For 1800S


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 1 Mm MG2+ For 1800S within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:23.6 occ:0.80 OD1 A:ASP13 2.0 35.5 1.0 O1B A:DTP503 2.1 23.5 0.8 O2G A:DTP503 2.1 29.3 0.8 OD2 A:ASP115 2.2 38.9 0.8 O1A A:DTP503 2.2 30.6 0.8 O A:MET14 2.2 28.9 1.0 CG A:ASP13 2.9 26.9 1.0 PB A:DTP503 3.1 31.1 0.8 OD2 A:ASP13 3.2 52.7 1.0 PG A:DTP503 3.3 30.7 0.8 C A:MET14 3.3 18.6 1.0 PA A:DTP503 3.3 38.1 0.8 O3A A:DTP503 3.4 34.4 0.8 CG A:ASP115 3.4 30.3 0.8 MG A:MG502 3.4 26.7 0.4 O3B A:DTP503 3.5 27.9 0.8 OD2 A:ASP115 3.7 25.2 0.2 C5' A:DTP503 3.8 33.3 0.8 CG A:ASP115 3.9 28.0 0.2 O3G A:DTP503 3.9 24.0 0.8 N A:MET14 4.0 16.3 1.0 OD1 A:ASP115 4.1 31.5 0.8 O A:HOH601 4.1 34.8 0.4 O5' A:DTP503 4.1 33.4 0.8 NZ A:LYS231 4.1 27.4 1.0 N A:ASP15 4.2 21.2 1.0 CA A:MET14 4.2 14.1 1.0 CB A:ASP13 4.2 21.2 1.0 N A:CYS16 4.2 22.9 1.0 C A:ASP13 4.3 17.4 1.0 CB A:ASP115 4.3 20.9 0.2 CA A:ASP15 4.4 20.8 1.0 CB A:ASP115 4.4 20.7 0.8 OD1 A:ASP115 4.4 29.1 0.2 C A:ASP15 4.5 20.7 1.0 O1G A:DTP503 4.5 30.6 0.8 O2B A:DTP503 4.5 25.2 0.8 O A:ASP115 4.5 23.6 1.0 O2A A:DTP503 4.5 38.8 0.8 CA A:ASP13 4.6 17.6 1.0 N A:PHE17 4.7 14.8 1.0 O A:ASP13 4.8 17.4 1.0 CB A:MET14 4.9 22.9 1.0 CA A:CYS16 5.0 20.0 1.0

Magnesium binding site 2 out of 2 in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 1 Mm MG2+ For 1800S


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 1 Mm MG2+ For 1800S within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg502 b:26.7 occ:0.40 O1A A:DTP503 2.2 30.6 0.8 OD1 A:ASP115 2.3 31.5 0.8 O A:HOH601 2.4 34.8 0.4 OD1 A:ASP115 2.4 29.1 0.2 C3' P:CAR9 2.6 33.7 0.3 OD2 A:ASP13 2.7 52.7 1.0 OE2 A:GLU116 2.7 40.6 1.0 O3' P:CAR9 2.7 32.1 0.3 OD2 A:ASP115 2.8 38.9 0.8 CG A:ASP115 2.8 30.3 0.8 CG A:ASP115 3.1 28.0 0.2 CD A:GLU116 3.4 36.8 1.0 CG A:ASP13 3.4 26.9 1.0 OD2 A:ASP115 3.4 25.2 0.2 PA A:DTP503 3.4 38.1 0.8 MG A:MG501 3.4 23.6 0.8 C4' P:CAR9 3.5 34.3 0.3 CG A:GLU116 3.6 46.7 1.0 CB A:GLU116 3.7 29.2 1.0 OD1 A:ASP13 3.8 35.5 1.0 C5' P:CAR9 3.8 32.7 0.3 C2' P:CAR9 3.9 35.0 0.3 O A:ASP115 3.9 23.6 1.0 O5' A:DTP503 3.9 33.4 0.8 O2A A:DTP503 4.0 38.8 0.8 C5' A:DTP503 4.0 33.3 0.8 O3' P:CAR9 4.1 37.9 0.7 OG A:SER113 4.1 24.8 1.0 C A:ASP115 4.1 25.8 1.0 CB A:ASP115 4.1 20.9 0.2 CB A:ASP115 4.2 20.7 0.8 OE1 A:GLU116 4.3 37.4 1.0 CB A:ASP13 4.4 21.2 1.0 O2' P:CAR9 4.4 36.4 0.3 N A:GLU116 4.4 20.7 1.0 CA A:GLU116 4.5 20.6 1.0 O2G A:DTP503 4.6 29.3 0.8 CA A:ASP115 4.7 20.1 0.2 CA A:ASP115 4.7 20.0 0.8 O3A A:DTP503 4.7 34.4 0.8 O1B A:DTP503 4.8 23.5 0.8 O4' P:CAR9 4.8 29.8 0.3 C3' P:CAR9 4.8 36.5 0.7 C1' P:CAR9 4.9 32.1 0.3 CA A:ASP13 5.0 17.6 1.0 NZ A:LYS224 5.0 34.9 1.0

C.Chang, Y.Gao. Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 1 Mm MG2+ For 1800S To Be Published.