Magnesium in PDB 8vmg: Crystal Structure of Gsk-3 26-383 Bound to Axin 383-435

All present enzymatic activity of Crystal Structure of Gsk-3 26-383 Bound to Axin 383-435:
2.7.11.1; 2.7.11.26;

The structure of Crystal Structure of Gsk-3 26-383 Bound to Axin 383-435, PDB code: 8vmg was solved by M.D.Enos, M.Gavagan, N.Jameson, J.G.Zalatan, W.I.Weis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.76 / 2.45
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	195.585, 195.585, 152.204, 90, 90, 120
R / Rfree (%)	19.5 / 23

The structure of Crystal Structure of Gsk-3 26-383 Bound to Axin 383-435 also contains other interesting chemical elements:

Chlorine

(Cl)

15 atoms

The binding sites of Magnesium atom in the Crystal Structure of Gsk-3 26-383 Bound to Axin 383-435 (pdb code 8vmg). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Gsk-3 26-383 Bound to Axin 383-435, PDB code: 8vmg:

Magnesium binding site 1 out of 1 in the Crystal Structure of Gsk-3 26-383 Bound to Axin 383-435


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Gsk-3 26-383 Bound to Axin 383-435 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg436 b:73.5 occ:1.00 OD2 A:ASP200 2.0 69.0 1.0 O A:HOH574 2.2 70.7 1.0 OD1 A:ASN186 2.3 63.4 1.0 O3A A:ADP401 2.5 84.6 0.8 CG A:ASP200 3.0 61.5 1.0 O A:HOH561 3.1 82.3 1.0 CG A:ASN186 3.1 57.5 1.0 O3B A:ADP401 3.2 69.4 0.8 ND2 A:ASN186 3.3 52.5 1.0 PB A:ADP401 3.4 107.0 0.8 O1A A:ADP401 3.4 91.2 0.8 CB A:ASP200 3.5 61.7 1.0 PA A:ADP401 3.6 75.3 0.8 O1B A:ADP401 3.8 100.2 0.8 OD1 A:ASP200 4.0 69.0 1.0 OD2 A:ASP181 4.5 50.8 1.0 CB A:ASN186 4.6 51.0 1.0 C5' A:ADP401 4.6 65.3 0.8 O2A A:ADP401 4.6 65.1 0.8 O2B A:ADP401 4.7 101.6 0.8 O5' A:ADP401 4.7 62.8 0.8 CL A:CL438 4.7 79.6 1.0 O3' A:ADP401 4.8 62.2 0.8 O A:HOH522 4.8 56.9 1.0 CA A:ASP200 5.0 52.3 1.0

M.D.Enos, M.Gavagan, N.Jameson, J.G.Zalatan, W.I.Weis. Structural and Functional Effects of Phosphopriming and Scaffolding in the Kinase GSK3BETA Sci.Signal. 2024.
ISSN: ESSN 1937-9145
DOI: 10.1126/SCISIGNAL.ADO0881