Magnesium in PDB 9bcv: Cyclase Domain of Gc-A Bound to Anp

All present enzymatic activity of Cyclase Domain of Gc-A Bound to Anp:
4.6.1.2;

The binding sites of Magnesium atom in the Cyclase Domain of Gc-A Bound to Anp (pdb code 9bcv). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Cyclase Domain of Gc-A Bound to Anp, PDB code: 9bcv:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Cyclase Domain of Gc-A Bound to Anp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cyclase Domain of Gc-A Bound to Anp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1103 b:45.1 occ:1.00 O1G A:G2P1101 2.0 134.1 1.0 O2B A:G2P1101 2.1 147.0 1.0 O A:ILE882 2.7 41.2 1.0 PG A:G2P1101 3.1 143.5 1.0 O3B A:G2P1101 3.2 151.4 1.0 PB A:G2P1101 3.2 151.8 1.0 O1A A:G2P1101 3.6 142.5 1.0 O3G A:G2P1101 3.9 140.0 1.0 OD2 A:ASP925 3.9 54.4 1.0 C A:ILE882 3.9 36.6 1.0 C5' A:G2P1101 4.0 143.4 1.0 CB A:PHE885 4.0 58.4 1.0 OD2 A:ASP881 4.0 54.4 1.0 OD1 A:ASP881 4.0 58.2 1.0 CG A:ASP881 4.2 58.2 1.0 C3A A:G2P1101 4.3 147.6 1.0 PA A:G2P1101 4.3 141.4 1.0 O5' A:G2P1101 4.3 145.3 1.0 N A:PHE885 4.3 54.9 1.0 O2G A:G2P1101 4.4 145.5 1.0 O1B A:G2P1101 4.4 145.8 1.0 OD1 A:ASP925 4.5 55.8 1.0 CG A:ASP925 4.6 52.2 1.0 N A:ILE882 4.7 35.0 1.0 CA A:VAL883 4.7 31.7 1.0 CA A:PHE885 4.8 59.3 1.0 N A:GLY884 4.8 36.7 1.0 N A:VAL883 4.8 30.4 1.0 CA A:ILE882 4.9 32.8 1.0

Magnesium binding site 2 out of 2 in the Cyclase Domain of Gc-A Bound to Anp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cyclase Domain of Gc-A Bound to Anp within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1101 b:50.3 occ:1.00 O2B A:G2P1102 2.0 186.9 1.0 OD2 B:ASP921 2.1 58.9 1.0 CG B:ASP921 2.8 54.6 1.0 OD1 B:ASP921 2.9 57.8 1.0 O B:ILE878 3.2 42.8 1.0 O2A A:G2P1102 3.4 197.5 1.0 PB A:G2P1102 3.5 189.3 1.0 C5' A:G2P1102 3.7 190.7 1.0 CB B:ASP921 4.2 49.1 1.0 CB B:PHE881 4.2 33.3 1.0 C B:ILE878 4.3 39.5 1.0 N B:ILE878 4.3 32.4 1.0 CB B:ASP877 4.4 26.5 1.0 O1B A:G2P1102 4.4 183.6 1.0 O3B A:G2P1102 4.4 188.3 1.0 PA A:G2P1102 4.4 190.1 1.0 OD2 B:ASP877 4.4 36.0 1.0 C3A A:G2P1102 4.5 196.4 1.0 O5' A:G2P1102 4.5 186.5 1.0 CA B:ILE878 4.8 34.1 1.0 CG B:ASP877 4.8 29.4 1.0 C4' A:G2P1102 4.9 188.8 1.0 CB B:ILE878 4.9 33.9 1.0 O4' A:G2P1102 4.9 190.6 1.0

S.Liu, A.M.Payne, J.Wang, L.Zhu, N.Paknejad, E.T.Eng, W.Liu, Y.Miao, R.K.Hite, X.Y.Huang. Architecture and Activation of Single-Pass Transmembrane Receptor Guanylyl Cyclase. Nat.Struct.Mol.Biol. 2024.
ISSN: ESSN 1545-9985
PubMed: 39543315
DOI: 10.1038/S41594-024-01426-Z