Magnesium in PDB 9cc0: Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form

All present enzymatic activity of Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form:
3.4.21.53;

The binding sites of Magnesium atom in the Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form (pdb code 9cc0). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form, PDB code: 9cc0:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1001 b:82.0 occ:1.00 OG1 A:THR530 2.0 82.9 1.0 O1G A:ATP1000 2.0 80.7 1.0 OD1 A:ASP590 3.3 98.2 1.0 CB A:THR530 3.4 82.9 1.0 PG A:ATP1000 3.4 80.7 1.0 OD2 A:ASP590 3.5 98.2 1.0 O2B A:ATP1000 3.6 80.7 1.0 CG A:ASP590 3.8 98.2 1.0 O3B A:ATP1000 3.9 80.7 1.0 O1A A:ATP1000 3.9 80.7 1.0 CG2 A:THR530 3.9 82.9 1.0 CG2 A:THR638 4.1 95.2 1.0 NH2 B:ARG652 4.3 80.7 1.0 O2G A:ATP1000 4.3 80.7 1.0 PB A:ATP1000 4.4 80.7 1.0 CA A:THR530 4.4 82.9 1.0 N A:THR530 4.5 82.9 1.0 O3G A:ATP1000 4.5 80.7 1.0 OE2 A:GLU591 4.6 101.8 1.0 OD2 B:ASP612 4.8 88.2 1.0 CB A:THR638 4.9 95.2 1.0 PA A:ATP1000 4.9 80.7 1.0 O3A A:ATP1000 5.0 80.7 1.0

Magnesium binding site 2 out of 4 in the Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1001 b:61.2 occ:1.00 OG1 B:THR530 2.0 59.3 1.0 O1G B:ATP1000 2.0 63.3 1.0 CB B:THR530 3.2 59.3 1.0 OD2 B:ASP590 3.3 68.4 1.0 OD1 B:ASP590 3.3 68.4 1.0 O1B B:ATP1000 3.4 63.3 1.0 PG B:ATP1000 3.5 63.3 1.0 CG B:ASP590 3.7 68.4 1.0 CG2 B:THR530 4.0 59.3 1.0 NH2 C:ARG652 4.0 66.8 1.0 O3B B:ATP1000 4.1 63.3 1.0 O3G B:ATP1000 4.2 63.3 1.0 PB B:ATP1000 4.2 63.3 1.0 OG1 B:THR638 4.3 64.6 1.0 CA B:THR530 4.3 59.3 1.0 N B:THR530 4.4 59.3 1.0 O1A B:ATP1000 4.5 63.3 1.0 O2G B:ATP1000 4.5 63.3 1.0 OD2 C:ASP612 4.7 68.7 1.0 O3A B:ATP1000 4.7 63.3 1.0 OE2 B:GLU591 4.9 72.0 1.0 CB B:THR638 5.0 64.6 1.0

Magnesium binding site 3 out of 4 in the Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg1001 b:71.1 occ:1.00 OG1 C:THR530 2.0 61.3 1.0 O1G C:ATP1000 2.0 66.1 1.0 OD2 C:ASP590 2.8 68.3 1.0 OD1 C:ASP590 3.1 68.3 1.0 CB C:THR530 3.2 61.3 1.0 CG C:ASP590 3.3 68.3 1.0 PG C:ATP1000 3.5 66.1 1.0 NE2 D:GLN615 3.5 75.8 1.0 CG2 C:THR530 3.6 61.3 1.0 OD2 D:ASP612 4.0 75.6 1.0 O3B C:ATP1000 4.1 66.1 1.0 O3G C:ATP1000 4.2 66.1 1.0 O1A C:ATP1000 4.3 66.1 1.0 CA C:THR530 4.4 61.3 1.0 NH2 D:ARG652 4.4 75.6 1.0 O2B C:ATP1000 4.5 66.1 1.0 OE2 C:GLU591 4.5 72.4 1.0 O2G C:ATP1000 4.5 66.1 1.0 CD D:GLN615 4.5 75.8 1.0 OG1 C:THR638 4.6 65.3 1.0 N C:THR530 4.7 61.3 1.0 CB C:ASP590 4.8 68.3 1.0 CG C:GLU591 4.9 72.4 1.0 OE1 D:GLN615 4.9 75.8 1.0

Magnesium binding site 4 out of 4 in the Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Human Mitochondrial LONP1 Degrading Casein, Atp-Bound Closed Form within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg1001 b:80.6 occ:1.00 O3G D:ATP1000 2.1 79.4 1.0 OG1 D:THR530 2.4 74.8 1.0 PG D:ATP1000 3.6 79.4 1.0 OG1 D:THR638 3.7 75.0 1.0 CB D:ASP590 3.8 82.8 1.0 CB D:THR530 3.8 74.8 1.0 OD2 D:ASP590 4.0 82.8 1.0 O3B D:ATP1000 4.2 79.4 1.0 O2B D:ATP1000 4.3 79.4 1.0 CG D:ASP590 4.4 82.8 1.0 O1G D:ATP1000 4.4 79.4 1.0 O2G D:ATP1000 4.5 79.4 1.0 N D:THR530 4.6 74.8 1.0 CG2 D:THR530 4.6 74.8 1.0 CB D:THR638 4.6 75.0 1.0 CA D:THR530 4.6 74.8 1.0 NH2 D:ARG546 4.8 78.9 1.0 CD2 D:LEU588 4.9 73.6 1.0 CG2 D:THR638 5.0 75.0 1.0 PB D:ATP1000 5.0 79.4 1.0

J.T.Mindrebo, G.C.Lander. Structural and Mechanistic Studies on Human LONP1 Redefine the Hand-Over-Hand Translocation Mechanism. Biorxiv 2024.
ISSN: ISSN 2692-8205
PubMed: 38979310
DOI: 10.1101/2024.06.24.600538