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Magnesium in PDB 9ci9: Crystal Structure of Human Polymerase Eta with Incoming Dcmpnpp Nucleotide Across Threofuranosyl Thymidine in Dna Template at Extension Stage
Enzymatic activity of Crystal Structure of Human Polymerase Eta with Incoming Dcmpnpp Nucleotide Across Threofuranosyl Thymidine in Dna Template at Extension Stage
All present enzymatic activity of Crystal Structure of Human Polymerase Eta with Incoming Dcmpnpp Nucleotide Across Threofuranosyl Thymidine in Dna Template at Extension Stage:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Crystal Structure of Human Polymerase Eta with Incoming Dcmpnpp Nucleotide Across Threofuranosyl Thymidine in Dna Template at Extension Stage, PDB code: 9ci9
was solved by
R.Tomar,
M.P.Stone,
M.Egli,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 36.81 / 2.09 |
| Space group | P 61 |
| Cell size a, b, c (Å), α, β, γ (°) | 98.902, 98.902, 81.54, 90, 90, 120 |
| R / Rfree (%) | 15.8 / 20.7 |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Human Polymerase Eta with Incoming Dcmpnpp Nucleotide Across Threofuranosyl Thymidine in Dna Template at Extension Stage
(pdb code 9ci9). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human Polymerase Eta with Incoming Dcmpnpp Nucleotide Across Threofuranosyl Thymidine in Dna Template at Extension Stage, PDB code: 9ci9:
Jump to Magnesium binding site number: 1; 2;
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human Polymerase Eta with Incoming Dcmpnpp Nucleotide Across Threofuranosyl Thymidine in Dna Template at Extension Stage, PDB code: 9ci9:
Jump to Magnesium binding site number: 1; 2;
Magnesium binding site 1 out of 2 in 9ci9
Go back to
Magnesium Binding Sites List in 9ci9
Magnesium binding site 1 out
of 2 in the Crystal Structure of Human Polymerase Eta with Incoming Dcmpnpp Nucleotide Across Threofuranosyl Thymidine in Dna Template at Extension Stage
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Crystal Structure of Human Polymerase Eta with Incoming Dcmpnpp Nucleotide Across Threofuranosyl Thymidine in Dna Template at Extension Stage within 5.0Å range:
|
Magnesium binding site 2 out of 2 in 9ci9
Go back to
Magnesium Binding Sites List in 9ci9
Magnesium binding site 2 out
of 2 in the Crystal Structure of Human Polymerase Eta with Incoming Dcmpnpp Nucleotide Across Threofuranosyl Thymidine in Dna Template at Extension Stage
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Crystal Structure of Human Polymerase Eta with Incoming Dcmpnpp Nucleotide Across Threofuranosyl Thymidine in Dna Template at Extension Stage within 5.0Å range:
|
Reference:
R.Tomar,
P.P.Ghodke,
A.Patra,
E.Smyth,
A.Pontarelli,
W.Copp,
F.P.Guengerich,
J.J.Chaput,
C.J.Wilds,
M.P.Stone,
M.Egli.
Dna Replication Across Alpha-L-(3'-2')-Threofuranosyl Nucleotides Mediated By Human Dna Polymerase Eta. Biochemistry 2024.
ISSN: ISSN 0006-2960
PubMed: 39259676
DOI: 10.1021/ACS.BIOCHEM.4C00387
Page generated: Sat Oct 5 08:56:23 2024
ISSN: ISSN 0006-2960
PubMed: 39259676
DOI: 10.1021/ACS.BIOCHEM.4C00387
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